6-O-benzylguanine

Generic Name
6-O-benzylguanine
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C12H11N5O
CAS Number
19916-73-5
Unique Ingredient Identifier
01KC87F8FE
Background

6-O-benzylguanine has been used in trials studying the treatment of HIV Infection, Adult Gliosarcoma, Adult Glioblastoma, Stage I Adult Hodgkin Lymphoma, and Stage II Adult Hodgkin Lymphoma, among others.

Associated Conditions
-
Associated Therapies
-

O6-benzylguanine and Carmustine in Treating Patients With Unresectable Locally Recurrent or Metastatic Melanoma

Phase 2
Completed
Conditions
Interventions
First Posted Date
2003-01-27
Last Posted Date
2013-02-11
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
40
Registration Number
NCT00005961
Locations
๐Ÿ‡บ๐Ÿ‡ธ

University of Illinois at Chicago Health Sciences Center, Chicago, Illinois, United States

๐Ÿ‡บ๐Ÿ‡ธ

Louis A. Weiss Memorial Hospital, Chicago, Illinois, United States

๐Ÿ‡บ๐Ÿ‡ธ

Evanston Northwestern Health Care, Evanston, Illinois, United States

and more 10 locations

O6-benzylguanine and Carmustine in Treating Patients With Stage IA-IIA Cutaneous T-cell Lymphoma

First Posted Date
2003-01-27
Last Posted Date
2013-01-11
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
20
Registration Number
NCT00003613
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Case Western Reserve University, Cleveland, Ohio, United States

S0001 RT and Carmustine With or Without O6BG in Patients With New Glioblastoma Multiforme or Gliosarcoma

First Posted Date
2003-01-27
Last Posted Date
2013-01-30
Lead Sponsor
SWOG Cancer Research Network
Target Recruit Count
183
Registration Number
NCT00017147
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Freeman Cancer Institute at Freeman Health System, Joplin, Missouri, United States

๐Ÿ‡บ๐Ÿ‡ธ

Great Falls Clinic, Great Falls, Montana, United States

๐Ÿ‡บ๐Ÿ‡ธ

Glacier Oncology, PLLC, Kalispell, Montana, United States

and more 160 locations

Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer

Phase 2
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2010-06-10
Lead Sponsor
Case Comprehensive Cancer Center
Target Recruit Count
13
Registration Number
NCT00005981
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Ireland Cancer Center at University Hospitals Case Medical Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Gene Therapy and Chemotherapy in Treating Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma

First Posted Date
2003-01-27
Last Posted Date
2010-06-11
Lead Sponsor
Case Comprehensive Cancer Center
Target Recruit Count
8
Registration Number
NCT00003567
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Ireland Cancer Center at University Hospitals Case Medical Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Temozolomide and O6-benzylguanine in Treating Patients With Newly Diagnosed, Recurrent, or Progressive Anaplastic Glioma

Phase 1
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-06-20
Lead Sponsor
Duke University
Registration Number
NCT00006474
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Duke Comprehensive Cancer Center, Durham, North Carolina, United States

O6-benzylguanine And Carmustine in Treating Patients With Multiple Myeloma

First Posted Date
2003-01-27
Last Posted Date
2010-06-11
Lead Sponsor
Case Comprehensive Cancer Center
Target Recruit Count
17
Registration Number
NCT00004072
Locations
๐Ÿ‡บ๐Ÿ‡ธ

MetroHealth Medical Center, Cleveland, Ohio, United States

๐Ÿ‡บ๐Ÿ‡ธ

University of Chicago Cancer Research Center, Chicago, Illinois, United States

๐Ÿ‡บ๐Ÿ‡ธ

Ireland Cancer Center at University Hospitals Case Medical Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Carmustine Implants and O(6)-Benzylguanine in Treating Children With Recurrent Malignant Glioma

Phase 1
Terminated
Conditions
First Posted Date
2003-01-27
Last Posted Date
2009-10-16
Lead Sponsor
Pediatric Brain Tumor Consortium
Target Recruit Count
3
Registration Number
NCT00045721
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Children's National Medical Center, Washington, District of Columbia, United States

๐Ÿ‡บ๐Ÿ‡ธ

Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute, Boston, Massachusetts, United States

๐Ÿ‡บ๐Ÿ‡ธ

Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States

and more 6 locations

Temozolomide and O6-benzylguanine in Treating Children With Solid Tumors

First Posted Date
2003-01-27
Last Posted Date
2015-04-29
Lead Sponsor
National Cancer Institute (NCI)
Registration Number
NCT00020150
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Warren Grant Magnuson Clinical Center - NCI Clinical Studies Support, Bethesda, Maryland, United States

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