Simtuzumab

Generic Name
Simtuzumab
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
1318075-13-6
Unique Ingredient Identifier
11Z5AIU653
Background

Simtuzumab has been used in trials studying the treatment and basic science of Myelofibrosis, Pancreatic Cancer, Colorectal Cancer, and Idiopathic Pulmonary Fibrosis.

Associated Conditions
-
Associated Therapies
-

Study to Assess the Efficacy and Safety of Simtuzumab (GS-6624) in Adults With Idiopathic Pulmonary Fibrosis (IPF)

First Posted Date
2013-01-16
Last Posted Date
2017-05-30
Lead Sponsor
Gilead Sciences
Target Recruit Count
544
Registration Number
NCT01769196
Locations
🇺🇸

Sarasota Memorial Hospital, Sarasota, Florida, United States

🇺🇸

University of Maryland, Baltimore, Maryland, United States

🇺🇸

University of Chicago, Chicago, Illinois, United States

and more 171 locations

Long-Term Safety Study of GS-6624 in Adults With Idiopathic Pulmonary Fibrosis (IPF)

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2013-01-03
Last Posted Date
2017-04-04
Lead Sponsor
Gilead Sciences
Target Recruit Count
34
Registration Number
NCT01759511
Locations
🇺🇸

Arizona Pulmonary Specialists, Ltd., Scottsdale, Arizona, United States

🇺🇸

Medical University of South Carolina, Charleston, South Carolina, United States

🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

and more 3 locations

A Study to Evaluate the Efficacy and Safety of Simtuzumab Combined With Gemcitabine for Metastatic Pancreatic Adenocarcinoma

First Posted Date
2011-11-16
Last Posted Date
2015-03-10
Lead Sponsor
Gilead Sciences
Target Recruit Count
250
Registration Number
NCT01472198
Locations
🇺🇸

UCLA Community Oncology Practice, Los Angeles, California, United States

🇺🇸

Northwestern University, Chicago, Illinois, United States

🇺🇸

Comprehensive Cancer Centers of Nevada, Henderson, Nevada, United States

and more 53 locations

Efficacy and Safety of Simtuzumab in Adults With Primary, Post Polycythemia Vera or Post Essential Thrombocythemia Myelofibrosis

Phase 2
Completed
Conditions
Interventions
First Posted Date
2011-06-09
Last Posted Date
2020-07-01
Lead Sponsor
Gilead Sciences
Target Recruit Count
54
Registration Number
NCT01369498
Locations
🇺🇸

Stanford University Medical center, Stanford, California, United States

🇺🇸

Oncology Hematology Care Clinical Trials, Cincinnati, Ohio, United States

🇺🇸

Mayo Clinic, Scottsdale, Arizona, United States

and more 4 locations

A Study to Evaluate the Safety and Efficacy of GS-6624 (Formerly AB0024) in Patients With Idiopathic Pulmonary Fibrosis

Phase 1
Completed
Conditions
Interventions
First Posted Date
2011-05-30
Last Posted Date
2015-07-09
Lead Sponsor
Gilead Sciences
Target Recruit Count
48
Registration Number
NCT01362231
Locations
🇺🇸

Loess Hills Clinical Research Center, Council Bluffs, Iowa, United States

🇺🇸

Stanford University Medical Center, Stanford, California, United States

🇺🇸

Medical University of South Carolina, Charleston, South Carolina, United States

and more 4 locations
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