Bemcentinib

Generic Name
Bemcentinib
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C30H34N8
CAS Number
1037624-75-1
Unique Ingredient Identifier
0ICW2LX8AS
Background

Bemcentinib has been investigated for the treatment of Non-Small Cell Lung Cancer.

Associated Conditions
-
Associated Therapies
-

Study of Bemcentinib Plus Pacritinib In Patients With Advanced Lung Adenocarcinoma

Phase 1
Not yet recruiting
Conditions
Interventions
First Posted Date
2024-07-24
Last Posted Date
2024-12-03
Lead Sponsor
The University of Texas Health Science Center at San Antonio
Target Recruit Count
44
Registration Number
NCT06516887
Locations
🇺🇸

University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States

A Phase 1 Study to Investigate 14C-bemcentinib Following Single Oral Administration in Healthy Male Subjects

First Posted Date
2024-06-21
Last Posted Date
2024-06-21
Lead Sponsor
BerGenBio ASA
Target Recruit Count
6
Registration Number
NCT06469138
Locations
🇬🇧

Labcorp Clinical Research Unit Ltd., Leeds, United Kingdom

A Study to Investigate the Safety, Tolerability, and Preliminary Anti-tumor Activity of Bemcentinib in Combination With Pembrolizumab Plus Pemetrexed and Carboplatin in Adult Participants With Untreated Non-squamous Non-small Cell Lung Cancer

First Posted Date
2022-07-21
Last Posted Date
2023-10-10
Lead Sponsor
BerGenBio ASA
Target Recruit Count
64
Registration Number
NCT05469178
Locations
🇺🇸

Tennessee Oncology PLLC, Nashville, Tennessee, United States

🇺🇸

Mount Sinai Comprehensive Cancer Center, Miami Beach, Florida, United States

🇺🇸

Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, Maryland, United States

and more 2 locations

A Study of Bemcentinib for the Treatment of COVID-19 in Hospitalised Patients

Phase 2
Completed
Conditions
Interventions
First Posted Date
2021-05-18
Last Posted Date
2024-10-16
Lead Sponsor
BerGenBio ASA
Target Recruit Count
115
Registration Number
NCT04890509
Locations
🇮🇳

Unity Trauma Center and ICU, Unity Hospital, Surat, Gujarat, India

🇿🇦

Lakeview Hospital, Mowbray, Benoni, South Africa

🇮🇳

Kasturba Medical College, Mangalore, Karnataka, India

and more 9 locations

Evaluating the Efficacy and Safety of Bemcentinib in Patients With Myelodysplastic Syndromes

First Posted Date
2019-01-31
Last Posted Date
2021-12-21
Lead Sponsor
GWT-TUD GmbH
Target Recruit Count
45
Registration Number
NCT03824080
Locations
🇳🇱

VU University Medical Center, Amsterdam, Netherlands

🇩🇪

Universitätsklinikum Dresden, Dresden, Germany

🇫🇷

CHU Hôtel Dieu Service d'Hématologie Clinique, Nantes, Nantes Cedex 1, France

and more 5 locations

Clinical Trial of Chemotherapy and Bemcentinib for Metastatic Pancreatic Cancer

First Posted Date
2018-08-28
Last Posted Date
2023-11-09
Lead Sponsor
University of Texas Southwestern Medical Center
Target Recruit Count
9
Registration Number
NCT03649321
Locations
🇺🇸

University of Texas Southwestern Medical Center, Dallas, Texas, United States

A Phase Ib/II Multicenter Open-label Study of Bemcentinib (BGB324) in Patients With AML or MDS

First Posted Date
2015-07-02
Last Posted Date
2024-12-19
Lead Sponsor
BerGenBio ASA
Target Recruit Count
122
Registration Number
NCT02488408
Locations
🇩🇪

Universitätsklinikum Ulm, Ulm, Germany

🇮🇹

Azienda Ospedaliero-Universitaria di Parma, Parma, Italy

🇩🇪

Medizinische Hochschule Hannover,Hämatologie, Hämostaseologie, Onkologie und Stammzelltransplantation,, Hannover, Carl-Neuberg-Str, Germany

and more 9 locations

A Study of BGB324(Bemcentinib) in Combination With Erlotinib in Patients With Non-Small Cell Lung Cancer

Phase 1
Completed
Conditions
Interventions
First Posted Date
2015-04-23
Last Posted Date
2022-08-18
Lead Sponsor
BerGenBio ASA
Target Recruit Count
40
Registration Number
NCT02424617
Locations
🇺🇸

University of Texas Southwestern Medical Center, Dallas, Texas, United States

🇺🇸

Moffit Cancer Centre, Tampa, Florida, United States

🇺🇸

Mary Crowley Cancer Research Unit, Dallas, Texas, United States

and more 7 locations
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