Methylprednisolone hemisuccinate
- Generic Name
- Methylprednisolone hemisuccinate
- Brand Names
- Solu-medrol
- Drug Type
- Small Molecule
- Chemical Formula
- C26H34O8
- CAS Number
- 2921-57-5
- Unique Ingredient Identifier
- 5GMR90S4KN
- Background
A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
- Associated Conditions
- Acute Gouty Arthritis, Ankylosing Spondylitis (AS), Berylliosis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatitis bullous, Dermatomyositis (DM), Edema of the cerebrum, Hypercalcemia of Malignancy, Immune Thrombocytopenia (ITP), Leukemias, Lymphoma, Multiple sclerosis exacerbation, Mycosis Fungoides (MF), Ophthalmia, Sympathetic, Pemphigus, Polymyositis, Primary adrenocortical insufficiency, Psoriatic Arthritis, Pure Red Cell Aplasia, Refractory Uveitis, Regional Enteritis, Rheumatoid Arthritis, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Acquired immune hemolytic anemia, Acute rheumatic carditis, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Fulminating Pulmonary Tuberculosis, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Severe Allergic Reactions, Symptomatic Sarcoidosis
- Associated Therapies
- Palliative Treatment
Impact of Local Steroid Application in Extreme Lateral Lumbar Interbody Fusion
- Conditions
- Interventions
- First Posted Date
- 2017-10-31
- Last Posted Date
- 2020-11-20
- Lead Sponsor
- Rush University Medical Center
- Registration Number
- NCT03327272
- Locations
- 🇺🇸
Rush University Medical Center, Chicago, Illinois, United States
Effect of Local Intraoperative Steroid on Dysphagia After ACDF
- First Posted Date
- 2017-10-17
- Last Posted Date
- 2020-11-20
- Lead Sponsor
- Rush University Medical Center
- Target Recruit Count
- 140
- Registration Number
- NCT03311425
Use of Local Intraoperative Steroid in MIS TLIF
- First Posted Date
- 2017-10-12
- Last Posted Date
- 2020-11-20
- Lead Sponsor
- Rush University Medical Center
- Target Recruit Count
- 105
- Registration Number
- NCT03308084
Zoledronic Acid or Methylprednisolone for Active Charcot's Neuroarthropathy of Foot in Patients With Diabetes Mellitus
- Conditions
- Interventions
- First Posted Date
- 2017-09-20
- Last Posted Date
- 2019-07-16
- Target Recruit Count
- 36
- Registration Number
- NCT03289338
- Locations
- 🇮🇳
Department of Endocrinology, PGIMER, Chandigarh, India
STeroids to REduce Systemic Inflammation After Infant Heart Surgery
- Conditions
- Interventions
- First Posted Date
- 2017-07-25
- Last Posted Date
- 2023-05-10
- Lead Sponsor
- Kevin Hill
- Target Recruit Count
- 1263
- Registration Number
- NCT03229538
- Locations
- 🇺🇸
Children's Hospital of Los Angeles, Los Angeles, California, United States
🇺🇸University of Colorado, Denver, Aurora, Colorado, United States
🇺🇸Children's Mercy Hospital, Kansas City, Missouri, United States
Autologous Stem Cell Transplant for Crohn's Disease
- Conditions
- Interventions
- First Posted Date
- 2017-07-17
- Last Posted Date
- 2024-09-30
- Lead Sponsor
- Aaron Etra
- Target Recruit Count
- 50
- Registration Number
- NCT03219359
- Locations
- 🇺🇸
Icahn School of Medicine at Mount Sinai, New York, New York, United States
Prospective Evaluation of Perioperative Steroid Dosing on Postsurgical Edema in Orthognathic Surgery
- First Posted Date
- 2017-06-19
- Last Posted Date
- 2021-08-03
- Lead Sponsor
- Jean Charles Doucet
- Target Recruit Count
- 180
- Registration Number
- NCT03190642
- Locations
- 🇨🇦
QE II Health Sciences Center, Halifax, Nova Scotia, Canada
GRAVITAS-301: A Study of Itacitinib or Placebo in Combination With Corticosteroids for Treatment of Acute Graft-Versus-Host Disease
- Conditions
- Interventions
- First Posted Date
- 2017-05-04
- Last Posted Date
- 2021-08-11
- Lead Sponsor
- Incyte Corporation
- Target Recruit Count
- 439
- Registration Number
- NCT03139604
- Locations
- 🇺🇸
University of Southern California, Los Angeles, California, United States
🇺🇸University of California, Los Angeles (UCLA) - Medical Center, Los Angeles, California, United States
🇺🇸Advocate Lutheran General Hospital - Oncology Specialists SC, Park Ridge, Illinois, United States
Glucocorticoids and Bone in Graves' Ophthalmopathy
- First Posted Date
- 2017-04-21
- Last Posted Date
- 2023-02-08
- Lead Sponsor
- Torben Harsløf
- Target Recruit Count
- 30
- Registration Number
- NCT03122847
- Locations
- 🇩🇰
Odense University Hospital, Odense, Denmark
🇩🇰Aarhus University Hospital, Aarhus C, Central Denmark Region, Denmark
A Phase 1 Study of Ruxolitinib, Steroids and Lenalidomide for Relapsed/Refractory Multiple Myeloma (RRMM) Patients
- Conditions
- Interventions
- First Posted Date
- 2017-04-12
- Last Posted Date
- 2023-11-01
- Lead Sponsor
- Oncotherapeutics
- Target Recruit Count
- 134
- Registration Number
- NCT03110822
- Locations
- 🇺🇸
Global Oncology, Inc., Alhambra, California, United States
🇺🇸Comprehensive Blood and Cancer Center, Bakersfield, California, United States
🇺🇸Robert A. Moss, M.D., F.A.C.P., Inc., Fountain Valley, California, United States
Drug Development Updates
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