Methylprednisolone hemisuccinate

Generic Name
Methylprednisolone hemisuccinate
Brand Names
Solu-medrol
Drug Type
Small Molecule
Chemical Formula
C26H34O8
CAS Number
2921-57-5
Unique Ingredient Identifier
5GMR90S4KN
Background

A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.

Associated Conditions
Acute Gouty Arthritis, Ankylosing Spondylitis (AS), Berylliosis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatitis bullous, Dermatomyositis (DM), Edema of the cerebrum, Hypercalcemia of Malignancy, Immune Thrombocytopenia (ITP), Leukemias, Lymphoma, Multiple sclerosis exacerbation, Mycosis Fungoides (MF), Ophthalmia, Sympathetic, Pemphigus, Polymyositis, Primary adrenocortical insufficiency, Psoriatic Arthritis, Pure Red Cell Aplasia, Refractory Uveitis, Regional Enteritis, Rheumatoid Arthritis, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Acquired immune hemolytic anemia, Acute rheumatic carditis, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Fulminating Pulmonary Tuberculosis, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Severe Allergic Reactions, Symptomatic Sarcoidosis
Associated Therapies
Palliative Treatment

Combination Chemotherapy in Treating Patients With Acute B-Lymphoblastic Leukemia or Non-Hodgkin's Lymphoma

Phase 2
Completed
Conditions
First Posted Date
2004-08-30
Last Posted Date
2013-06-20
Lead Sponsor
Memorial Sloan Kettering Cancer Center
Registration Number
NCT00002471
Locations
🇺🇸

Kaplan Cancer Center, New York, New York, United States

🇺🇸

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, United States

🇺🇸

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

and more 1 locations

Chemotherapy, Radiation Therapy, and Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer

First Posted Date
2004-08-04
Last Posted Date
2011-03-07
Lead Sponsor
Roswell Park Cancer Institute
Target Recruit Count
3
Registration Number
NCT00003661
Locations
🇺🇸

North Shore University Hospital, Manhasset, New York, United States

🇺🇸

Nemours Children's Clinic, Jacksonville, Florida, United States

🇺🇸

Cardinal Glennon Children's Hospital, Saint Louis, Missouri, United States

and more 14 locations

Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer or Other Hematologic or Metabolic Diseases

First Posted Date
2004-08-04
Last Posted Date
2011-03-07
Lead Sponsor
Roswell Park Cancer Institute
Target Recruit Count
90
Registration Number
NCT00003662
Locations
🇺🇸

Hackensack University Medical Center, Hackensack, New Jersey, United States

🇺🇸

St. Christopher's Hospital for Children, Philadelphia, Pennsylvania, United States

🇺🇸

University of Florida Health Science Center, Gainesville, Florida, United States

and more 12 locations

Combination Chemotherapy in Treating Patients With Intermediate-Grade or Immunoblastic Non-Hodgkin's Lymphoma

First Posted Date
2004-06-30
Last Posted Date
2018-11-14
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
61
Registration Number
NCT00002565
Locations
🇺🇸

University of Texas - MD Anderson Cancer Center, Houston, Texas, United States

🇧🇷

Faculdade de Medicina do ABC, Sao Paulo, Brazil

🇨🇱

Clinica Alemana, Santiago, Chile

Colony-Stimulating Factors to Relieve Neutropenia in Patients With Recurrent Non-Hodgkin's Lymphoma

First Posted Date
2004-06-25
Last Posted Date
2023-12-27
Lead Sponsor
University of Nebraska
Target Recruit Count
60
Registration Number
NCT00004192
Locations
🇺🇸

Ireland Cancer Center, Cleveland, Ohio, United States

🇺🇸

Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, United States

🇺🇸

University of Nebraska Medical Center, Omaha, Nebraska, United States

Combination Chemotherapy, Bone Marrow Transplantation, and Radiation Therapy in Treating Infants With Acute Lymphoblastic Leukemia

Phase 2
Completed
Conditions
First Posted Date
2004-06-16
Last Posted Date
2014-07-24
Lead Sponsor
Children's Oncology Group
Registration Number
NCT00002785
Locations
🇺🇸

Children's Hospital Los Angeles, Los Angeles, California, United States

🇺🇸

Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States

🇺🇸

Ireland Cancer Center, Cleveland, Ohio, United States

and more 30 locations
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