Fenebrutinib

Generic Name
Fenebrutinib
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C37H44N8O4
CAS Number
1434048-34-6
Unique Ingredient Identifier
E9L2885WUL
Background

Fenebrutinib is under investigation in clinical trial NCT03174041 (A Drug-Drug Interaction Study Between GDC-0853 and Midazolam, Itraconazole, Rosuvastatin, and Simvastatin).

Associated Conditions
-
Associated Therapies
-

A Study to Investigate the Efficacy of Fenebrutinib in Relapsing Multiple Sclerosis (RMS)

Phase 2
Active, not recruiting
Conditions
Interventions
First Posted Date
2021-11-15
Last Posted Date
2024-12-12
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
109
Registration Number
NCT05119569
Locations
🇷🇸

Clinical Center Nis, NIS, Serbia

🇺🇸

Fullerton Neurology and Headache Center, Fullerton, California, United States

🇺🇸

Cleveland Clinic Lou Ruvo; Center for Brain Research, Las Vegas, Nevada, United States

and more 14 locations

A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Teriflunomide in Relapsing Multiple Sclerosis (RMS)

Phase 3
Active, not recruiting
Conditions
Interventions
First Posted Date
2020-10-14
Last Posted Date
2024-12-06
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
746
Registration Number
NCT04586010
Locations
🇺🇸

Johns Hopkins University School Of Medicine; Outpatient Center, Baltimore, Maryland, United States

🇺🇸

OhioHealth, Columbus, Ohio, United States

🇺🇸

The Boster Center for MS, Columbus, Ohio, United States

and more 163 locations

Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Teriflunomide in Relapsing Multiple Sclerosis (RMS)

Phase 3
Active, not recruiting
Conditions
Interventions
First Posted Date
2020-10-14
Last Posted Date
2024-11-22
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
751
Registration Number
NCT04586023
Locations
🇦🇹

Kepler Universitätskliniken GmbH - Med Campus III; Neurologie & Psychiatrie, Linz, Austria

🇦🇹

Medizinische Universität Wien; Univ.Klinik fuer Neurologie, Wien, Austria

🇧🇷

L2 Ip Instituto de Pesquisas Clinicas Ltda ME; Centro Medico Hospitalar, Brasilia, DF, Brazil

and more 114 locations

A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Ocrelizumab in Adult Participants With Primary Progressive Multiple Sclerosis

First Posted Date
2020-09-10
Last Posted Date
2024-10-29
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
985
Registration Number
NCT04544449
Locations
🇦🇷

Focus CECIC, Buenos Aires, Argentina

🇺🇸

Alabama Neurology Associates, Homewood, Alabama, United States

🇺🇸

Sutter East Bay Medical Foundation, Berkeley, California, United States

and more 190 locations

Study Investigating a Single Oral Dose of Fenebrutinib in Healthy Volunteers

Phase 1
Completed
Conditions
Interventions
First Posted Date
2018-07-24
Last Posted Date
2018-12-06
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
8
Registration Number
NCT03596632
Locations
🇺🇸

Covance Clinical Research Unit, Inc, Madison, Wisconsin, United States

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