Pepinemab

Generic Name
Pepinemab
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
2097151-87-4
Unique Ingredient Identifier
BPZ4A29SYE
Background

Pepinemab is under investigation in clinical trial NCT03769155 (VX15/2503 With or Without Ipilimumab and/or Nivolumab in Patients With Resectable Stage IIIB-D Melanoma).

Associated Conditions
-
Associated Therapies
-

Adoptive T Cell Therapy Following HER2-Pulsed Dendritic Cell Vaccine & Pepinemab /Trastuzumab in Patients w/ Metastatic HER2+ Breast Cancer

First Posted Date
2022-05-18
Last Posted Date
2024-12-06
Lead Sponsor
H. Lee Moffitt Cancer Center and Research Institute
Target Recruit Count
28
Registration Number
NCT05378464
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Moffitt Cancer Center, Tampa, Florida, United States

SEMA4D Blockade Safety and Brain Metabolic Activity in Alzheimer's Disease (AD)

Phase 1
Completed
Conditions
Interventions
First Posted Date
2020-05-08
Last Posted Date
2024-08-22
Lead Sponsor
Vaccinex Inc.
Target Recruit Count
50
Registration Number
NCT04381468
Locations
๐Ÿ‡บ๐Ÿ‡ธ

University of Rochester Medical Center, Rochester, New York, United States

๐Ÿ‡บ๐Ÿ‡ธ

Indiana University School of Medicine, Indianapolis, Indiana, United States

๐Ÿ‡บ๐Ÿ‡ธ

JEM Research Institute, Lake Worth, Florida, United States

and more 10 locations

A Study in Subjects With Late Prodromal & Early Manifest HD to Assess the Safety, Tolerability, pk, and Efficacy of Pepi

Phase 2
Completed
Conditions
Interventions
First Posted Date
2015-06-25
Last Posted Date
2022-05-02
Lead Sponsor
Vaccinex Inc.
Target Recruit Count
301
Registration Number
NCT02481674
Locations
๐Ÿ‡บ๐Ÿ‡ธ

University of Vermont, Burlington, Vermont, United States

๐Ÿ‡บ๐Ÿ‡ธ

University of California, San Diego, La Jolla, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

Johns Hopkins University, Baltimore, Maryland, United States

and more 28 locations

Evaluation of Safety, Tolerability, and PK of VX15/2503 In Patients With MS

Phase 1
Completed
Conditions
Interventions
First Posted Date
2013-01-10
Last Posted Date
2015-02-06
Lead Sponsor
Vaccinex Inc.
Target Recruit Count
50
Registration Number
NCT01764737
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Wayne State University - University Health Center, Detroit, Michigan, United States

๐Ÿ‡บ๐Ÿ‡ธ

University of Colorado Hospital, Aschutz Inpatient Pavilion, Aurora, Colorado, United States

๐Ÿ‡บ๐Ÿ‡ธ

North Central Neurology Associates, PC, Cullman, Alabama, United States

and more 7 locations

Evaluation of Safety, Tolerability, PK & PD of Intravenous VX15/2503 in Patients With Advanced Solid Tumors

Phase 1
Completed
Conditions
Interventions
First Posted Date
2011-03-11
Last Posted Date
2014-08-13
Lead Sponsor
Vaccinex Inc.
Target Recruit Count
42
Registration Number
NCT01313065
Locations
๐Ÿ‡บ๐Ÿ‡ธ

South Texas Accelerated Research Therapeutics, LLC, San Antonio, Texas, United States

๐Ÿ‡บ๐Ÿ‡ธ

Virginia G. Piper Cancer Center at Scottsdale Healthcare, Scottsdale, Arizona, United States

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