Olinciguat

Generic Name
Olinciguat
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C21H16F5N7O3
CAS Number
1628732-62-6
Unique Ingredient Identifier
PD5F4ZXD21
Background

Olinciguat is under investigation in clinical trial NCT03892499 (A Trial to Evaluate the Effect of Itraconazole (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of the Soluble Guanylate Cyclase Stimulator, Olinciguat (IW-1701), in Healthy Volunteers).

Associated Conditions
-
Associated Therapies
-
Clinical Trials
Related News

A Trial to Evaluate the Effect of Itraconazole (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of the Soluble Guanylate Cyclase Stimulator, Olinciguat (IW-1701), in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: Olinciguat
Drug: Itraconazole
First Posted Date
2019-03-27
Last Posted Date
2019-07-15
Lead Sponsor
Cyclerion Therapeutics
Target Recruit Count
24
Registration Number
NCT03892499
Locations
🇺🇸

PPD, Austin, Texas, United States

Study of IW-1701, A Stimulator of Soluble Guanylate Cyclase (sGC), in Patients With Type I or II Achalasia

Phase 2
Terminated
Conditions
Achalasia
Interventions
Drug: Matching Placebo
Drug: Olinciguat
First Posted Date
2016-10-13
Last Posted Date
2021-05-04
Lead Sponsor
Cyclerion Therapeutics
Target Recruit Count
9
Registration Number
NCT02931565
Locations
🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

🇺🇸

University of Utah School of Medicine, Division of Gastroenterology, Hepatology & Nutrition, Salt Lake City, Utah, United States

and more 2 locations
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