Silmitasertib

Generic Name
Silmitasertib
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C19H12ClN3O2
CAS Number
1009820-21-6
Unique Ingredient Identifier
C6RWP0N0L2
Background

Silmitasertib is under investigation in clinical trial NCT03904862 (Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have Surgery).

Associated Conditions
-
Associated Therapies
-

Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

First Posted Date
2024-08-07
Last Posted Date
2024-11-01
Lead Sponsor
Milton S. Hershey Medical Center
Target Recruit Count
114
Registration Number
NCT06541262
Locations
🇺🇸

Penn State Milton S. Hershey Medical Center and Children's Hospital, Hershey, Pennsylvania, United States

Silmitasertib (CX-4945) in Patients With Severe Coronavirus Disease 2019 (COVID-19)

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2020-12-16
Last Posted Date
2023-11-07
Lead Sponsor
University of Arizona
Target Recruit Count
31
Registration Number
NCT04668209
Locations
🇺🇸

Banner University Medical Center Phoenix, Phoenix, Arizona, United States

🇺🇸

Banner University Medical Center Tucson, Tucson, Arizona, United States

Evaluating Safety, Pharmacokinetics and Clinical Benefit of Silmitasertib (CX-4945) in Subjects With Moderate COVID-19

Phase 2
Completed
Conditions
Interventions
First Posted Date
2020-12-11
Last Posted Date
2024-12-16
Lead Sponsor
Senhwa Biosciences, Inc.
Target Recruit Count
20
Registration Number
NCT04663737
Locations
🇺🇸

Center for Advanced Research and Education, Gainesville, Georgia, United States

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