Cetrelimab

Generic Name
Cetrelimab
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
2050478-92-5
Unique Ingredient Identifier
LYK98WP91F
Background

Cetrelimab is under investigation in clinical trial NCT03547037 (A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of JNJ-63723283, an Anti-Programmed Cell Death (PD)-1 Monoclonal Antibody, as Monotherapy or in Combination With Erdafitinib in Japanese Participants With Advanced Solid Cancers).

Associated Conditions
-
Associated Therapies
-

CD8 PET Imaging in Metastatic Solid Tumours

First Posted Date
2024-08-02
Last Posted Date
2024-12-13
Lead Sponsor
University Medical Center Groningen
Target Recruit Count
30
Registration Number
NCT06534190
Locations
🇳🇱

VUMC, Amsterdam, Netherlands

🇳🇱

University Medical Center Groningen, Groningen, Netherlands

🇬🇧

University of Cambridge, Cambridge, United Kingdom

and more 1 locations

A Study of JNJ-87704916, as Monotherapy and in Combination for Advanced Solid Tumors

Phase 1
Recruiting
Conditions
Interventions
First Posted Date
2024-03-15
Last Posted Date
2024-12-10
Lead Sponsor
Johnson & Johnson Enterprise Innovation Inc.
Target Recruit Count
96
Registration Number
NCT06311578
Locations
🇪🇸

Hosp Univ Vall D Hebron, Barcelona, Spain

🇺🇸

Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States

🇺🇸

UPMC Cancer Centers, Pittsburgh, Pennsylvania, United States

and more 4 locations

A Study of JNJ-86974680 in Participants With Advanced Non-small Cell Lung Cancer

First Posted Date
2023-11-03
Last Posted Date
2024-12-06
Lead Sponsor
Johnson & Johnson Enterprise Innovation Inc.
Target Recruit Count
76
Registration Number
NCT06116786
Locations
🇺🇸

Next Virginia, Fairfax, Virginia, United States

🇩🇪

Charite Research Organisation GmbH, Berlin, Germany

🇩🇪

Universitaetsklinikum Giessen und Marburg GmbH, Giessen, Germany

and more 7 locations

A Study of Combination Therapy With Amivantamab and Cetrelimab in Participants With Metastatic Non-small Cell Lung Cancer

First Posted Date
2023-06-18
Last Posted Date
2024-12-06
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
80
Registration Number
NCT05908734
Locations
🇰🇷

Samsung Medical Center, Seoul, Korea, Republic of

🇲🇾

University Malaya Medical Centre, Kuala Lumpur, Malaysia

🇧🇷

Fundacao Antonio Prudente A C Camargo Cancer Center, Sao Paulo, Brazil

and more 35 locations

A Study of JNJ-78278343 in Combination With Either JNJ-63723283 (Cetrelimab), Taxane Chemotherapy, or Androgen Receptor Pathway Inhibitors for Metastatic Castration-Resistant Prostate Cancer

First Posted Date
2023-04-19
Last Posted Date
2024-12-10
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
200
Registration Number
NCT05818683
Locations
🇺🇸

Washington University School Of Medicine, Saint Louis, Missouri, United States

🇺🇸

Sidney Kimmel Cancer Center - Jefferson Health, Philadelphia, Pennsylvania, United States

🇺🇸

Florida Cancer Specialists, Sarasota, Florida, United States

and more 5 locations

A Study of TAR-200 in Combination With Cetrelimab or TAR-200 Alone Versus Intravesical Bacillus Calmette-Guérin (BCG) in Participants With BCG-naïve High-risk Non-muscle Invasive Bladder Cancer (HR-NMIBC)

Phase 3
Active, not recruiting
Conditions
Interventions
First Posted Date
2023-02-06
Last Posted Date
2024-12-05
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
1135
Registration Number
NCT05714202
Locations
🇺🇸

Northwestern University, Chicago, Illinois, United States

🇧🇷

Liga Paranaense de Combate ao Cancer, Curitiba, Brazil

🇧🇷

Hospital Regional do Cancer - Hospital de Esperança, Presidente Prudente, Brazil

and more 240 locations

A Study of Cetrelimab in Participants With Chronic Hepatitis B Virus Infection

Phase 1
Completed
Conditions
Interventions
First Posted Date
2022-02-16
Last Posted Date
2023-07-24
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
11
Registration Number
NCT05242445
Locations
🇧🇪

SGS Belgium NV, Edegem, Belgium

🇪🇸

Hosp. Gral. Univ. Valencia, Valencia, Spain

🇵🇱

PUNKT ZDROWIA Hlebowicz Jakubowski Lekarze sp.p., Gdansk, Poland

and more 10 locations

A Study of TAR-200 in Combination With Cetrelimab and Cetrelimab Alone in Participants With Muscle-Invasive Urothelial Carcinoma of the Bladder

Phase 2
Active, not recruiting
Conditions
Interventions
First Posted Date
2021-06-09
Last Posted Date
2024-12-05
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
163
Registration Number
NCT04919512
Locations
🇺🇸

University of Alabama at Birmingham, Birmingham, Alabama, United States

🇺🇸

Urological Associates of Southern Arizona, P.C., Tucson, Arizona, United States

🇺🇸

UAMS Winthrop P. Rockefeller Cancer Institute, Little Rock, Arkansas, United States

and more 105 locations

A Study of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-invasive Bladder Cancer (MIBC) of the Bladder

First Posted Date
2020-12-09
Last Posted Date
2024-12-05
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
518
Registration Number
NCT04658862
Locations
🇺🇸

University of Southern California, Los Angeles, California, United States

🇦🇷

Centro Oncologico Riojano Integral (Cori), La Rioja, Argentina

🇧🇷

Fundacao Pio XII, Barretos, Brazil

and more 290 locations

A Study of TAR-200 in Combination With Cetrelimab, TAR-200 Alone, or Cetrelimab Alone in Participants With Non-Muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Intravesical Bacillus Calmette-Guérin Who Are Ineligible for or Elected Not to Undergo Radical Cystectomy

Phase 2
Active, not recruiting
Conditions
Interventions
First Posted Date
2020-11-23
Last Posted Date
2024-12-05
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
220
Registration Number
NCT04640623
Locations
🇺🇸

Urological Associates of Southern Arizona, P.C., Tucson, Arizona, United States

🇺🇸

University of Southern California, Los Angeles, California, United States

🇺🇸

Genesis Healthcare Partners - Genesis Research Greater Los Angeles, Sherman Oaks, California, United States

and more 140 locations
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