Fluoroestradiol F-18

Generic Name
Fluoroestradiol F-18
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C18H23FO2
CAS Number
94153-53-4
Unique Ingredient Identifier
T32277KB09
Background

Fluoroestradiol F-18 is an imaging agent used with positron emission tomography (PET) to detect estrogen receptor-positive breast cancer lesions. The ability to image ER-positive tumors in vivo is advantageous in that, while helping to visualize tumor progression/regression, it may also be used to assess for heterogeneity in ER expression across metastases (...

Indication

Fluoroestradiol F-18 is a radioactive diagnostic agent indicated for use with positron emission tomography (PET) imaging for the detection of estrogen receptor-positive lesions as an adjunct to biopsy in patients with recurrent or metastatic breast cancer.

Associated Conditions
Metastatic Estrogen Receptor Positive Breast Cancer, Recurrent Estrogen Receptor Positive Breast Cancer
Associated Therapies
-

Serial FES PET/CT to Measure Hormone Expression in Patients Undergoing Endocrine Targeted Therapy

First Posted Date
2020-12-31
Last Posted Date
2024-10-21
Lead Sponsor
University of Washington
Target Recruit Count
2
Registration Number
NCT04692103
Locations
🇺🇸

Fred Hutch/University of Washington Cancer Consortium, Seattle, Washington, United States

Evaluating Endometriosis With 16α-(18)F-fluoro-17β-estradiol ([F-18] FES) PET/MRI

Phase 1
Withdrawn
Conditions
Interventions
First Posted Date
2020-04-15
Last Posted Date
2024-05-10
Lead Sponsor
Annie (Annie) T. Packard
Registration Number
NCT04347135
Locations
🇺🇸

Mayo Clinic in Rochester, Rochester, Minnesota, United States

Hybrid Molecular Imaging of ER in Breast Cancer Patients With DCIS

First Posted Date
2018-10-12
Last Posted Date
2024-01-19
Lead Sponsor
University of Wisconsin, Madison
Target Recruit Count
13
Registration Number
NCT03703492
Locations
🇺🇸

University of Wisconsin Carbone Cancer Center, Madison, Wisconsin, United States

FES PET/CT in Predicting Response in Patients With Newly Diagnosed Metastatic Breast Cancer Receiving Endocrine Therapy

First Posted Date
2015-03-26
Last Posted Date
2024-10-08
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
99
Registration Number
NCT02398773
Locations
🇺🇸

University of Pennsylvania/Abramson Cancer Center, Philadelphia, Pennsylvania, United States

🇺🇸

UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas, United States

🇺🇸

Los Angeles General Medical Center, Los Angeles, California, United States

and more 22 locations

18F-FES PET/CT in Imaging Patients With Desmoid Tumors

First Posted Date
2015-03-02
Last Posted Date
2019-10-03
Lead Sponsor
Vanderbilt-Ingram Cancer Center
Target Recruit Count
3
Registration Number
NCT02374931
Locations
🇺🇸

Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, United States

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