ARO-APOC3

Generic Name
ARO-APOC3
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
-
Unique Ingredient Identifier
-
Background

ARO-APOC3 is an investigational RNAi therapeutic targeting apolipoprotein C-III (APOC3). It received an Orphan Drug designation by the FDA for the treatment of familial chylomicronemia syndrome.

Associated Conditions
-
Associated Therapies
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Study of ARO-APOC3 in Adults With Dyslipidemia

Phase 2
Active, not recruiting
Conditions
Interventions
First Posted Date
2022-06-09
Last Posted Date
2023-10-25
Lead Sponsor
Arrowhead Pharmaceuticals
Target Recruit Count
418
Registration Number
NCT05413135
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Preventive Cardiology Inc., Boca Raton, Florida, United States

๐Ÿ‡บ๐Ÿ‡ธ

A&R Research Group, Pembroke Pines, Florida, United States

๐Ÿ‡บ๐Ÿ‡ธ

Alta Pharmaceutical Research Center, Dunwoody, Georgia, United States

and more 60 locations

Study of ARO-APOC3 in Adults With Mixed Dyslipidemia

Phase 2
Completed
Conditions
Interventions
First Posted Date
2021-08-10
Last Posted Date
2024-04-18
Lead Sponsor
Arrowhead Pharmaceuticals
Target Recruit Count
353
Registration Number
NCT04998201
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Alta Pharmaceutical Research Center, Dunwoody, Georgia, United States

๐Ÿ‡บ๐Ÿ‡ธ

Preventive Cardiology Inc., Boca Raton, Florida, United States

๐Ÿ‡บ๐Ÿ‡ธ

A & R Research Group, Pembroke Pines, Florida, United States

and more 27 locations

Study to Evaluate ARO-APOC3 in Adults With Severe Hypertriglyceridemia

Phase 2
Completed
Conditions
Interventions
First Posted Date
2021-01-22
Last Posted Date
2024-04-18
Lead Sponsor
Arrowhead Pharmaceuticals
Target Recruit Count
229
Registration Number
NCT04720534
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Pioneer Research Solutions, Inc., Houston, Texas, United States

๐Ÿ‡บ๐Ÿ‡ธ

Clinical Research of South Nevada, Las Vegas, Nevada, United States

๐Ÿ‡บ๐Ÿ‡ธ

AppleMed Research Group, Miami, Florida, United States

and more 71 locations

Study of ARO-APOC3 in Healthy Volunteers, Hypertriglyceridemic Patients and Patients With Familial Chylomicronemia Syndrome (FCS)

First Posted Date
2018-12-21
Last Posted Date
2021-03-03
Lead Sponsor
Arrowhead Pharmaceuticals
Target Recruit Count
112
Registration Number
NCT03783377
Locations
๐Ÿ‡ฆ๐Ÿ‡บ

Linear Clinical Research, Perth, Western Australia, Australia

๐Ÿ‡ฆ๐Ÿ‡บ

Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia

๐Ÿ‡ฆ๐Ÿ‡บ

Royal Adelaide Hospital, Adelaide, South Australia, Australia

and more 7 locations
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