BTZ-043

Generic Name
BTZ-043
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C17H16F3N3O5S
CAS Number
1161233-85-7
Unique Ingredient Identifier
G55ZH52P57
Associated Conditions
-
Associated Therapies
-

Platform Assessing Regimens and Durations In a Global Multisite Consortium for TB

First Posted Date
2023-11-02
Last Posted Date
2024-10-16
Lead Sponsor
University College, London
Target Recruit Count
2500
Registration Number
NCT06114628
Locations
🇿🇦

TASK Eden, George, South Africa

🇹🇿

NIMR Mbeya, Mbeya, Tanzania

🇿🇦

TASK Brooklyn, Cape Town, South Africa

and more 5 locations

BTZ-043 Dose Evaluation in Combination and Selection

First Posted Date
2023-07-03
Last Posted Date
2023-12-22
Lead Sponsor
Michael Hoelscher
Target Recruit Count
90
Registration Number
NCT05926466
Locations
🇹🇿

National Institute for Medical Research (NIMR-Mwanza),, Mwanza, Tanzania

🇿🇦

TASK Applied Sciences Clinical Research Centre, Cape Town, South Africa

🇹🇿

National Institute for Medical Research (NIMR-MMRC), Mbeya, Tanzania

and more 1 locations

PanACEA - STEP2C -01

First Posted Date
2023-04-11
Last Posted Date
2024-04-17
Lead Sponsor
Michael Hoelscher
Target Recruit Count
270
Registration Number
NCT05807399
Locations
🇲🇼

Kamuzu College of Health Sciences (formerly College of Medicine), Blantyre, Malawi

🇹🇿

Kilimanjaro Clinical Research Institute (KCRI), Moshi, Tanzania

🇺🇬

Makerere University Lung Institute Limited, Kampala, Uganda

and more 5 locations

Early Bactericidal Activity, Safety & Tolerability of Oral GSK3036656 in a Dual Combination With Novel and Established Antitubercular Agents, or Standard of Care in Adults With Rifampicin Susceptible Pulmonary Tuberculosis

First Posted Date
2022-05-19
Last Posted Date
2024-02-22
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
128
Registration Number
NCT05382312
Locations
🇿🇦

GSK Investigational Site, Cape Town, South Africa

BTZ-043 - Multiple Ascending Dose (MAD) to Evaluate Safety, Tolerability and Early Bactericidal Activity (EBA)

First Posted Date
2019-08-02
Last Posted Date
2022-08-10
Lead Sponsor
Michael Hoelscher
Target Recruit Count
77
Registration Number
NCT04044001
Locations
🇿🇦

TASK Applied Sciences Clinical Research Centre, Cape Town, South Africa

🇿🇦

University of Cape Town Lung Institute (UCTLI), Cape Town, South Africa

A Single Ascending Dose Study of BTZ043

First Posted Date
2018-07-18
Last Posted Date
2019-03-07
Lead Sponsor
Michael Hoelscher
Target Recruit Count
30
Registration Number
NCT03590600
Locations
🇩🇪

Nuvisan, Neu-Ulm, Bavaria, Germany

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