DaxibotulinumtoxinA
- Generic Name
- DaxibotulinumtoxinA
- Brand Names
- Botox, Botox Cosmetic, Daxxify, Dysport, Xeomin
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 93384-43-1
- Unique Ingredient Identifier
- E211KPY694
- Background
DaxibotulinumtoxinA is an acetylcholine release inhibitor and neuromuscular blocking agent. It is a botulinum toxin without accessory proteins purified from the bacterium Clostridium botulinum type A, the gram-positive anaerobic bacterium primarily present in soil. C. botulinum is known to produce toxins that can cause botulism in humans.
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- Indication
DaxibotulinumtoxinA is indicated for the temporary improvement in the appearance of moderate to severe glabellar lines associated with corrugator and/or procerus muscle activity in adult patients. It is also used for the treatment of cervical dystonia in adult patients.
- Associated Conditions
- Cervical Dystonia, Moderate Glabellar Frown Lines (GL), Severe Glabellar Frown Lines (GL)
- Associated Therapies
- -
Study of a New Generation Botulinum Toxin A2NTX to Treat Spasticity After Stroke
- First Posted Date
- 2013-07-29
- Last Posted Date
- 2014-01-10
- Lead Sponsor
- University of Tokushima
- Target Recruit Count
- 30
- Registration Number
- NCT01910363
- Locations
- 🇯🇵
Tokushima University Hospital, Tokushima, Japan
Injection of Botox in the Perineal Muscles in Resistant Cases of Vaginal Spasm
- First Posted Date
- 2013-05-22
- Last Posted Date
- 2015-04-14
- Lead Sponsor
- Abdel-Maguid Ramzy
- Target Recruit Count
- 32
- Registration Number
- NCT01859507
- Locations
- 🇪🇬
AbdelMaguid Ramzy, Cairo, Egypt
Use of Botox to Treat Scrotal Pain
- First Posted Date
- 2013-04-15
- Last Posted Date
- 2014-09-01
- Lead Sponsor
- Mount Sinai Hospital, Canada
- Target Recruit Count
- 20
- Registration Number
- NCT01832194
- Locations
- 🇨🇦
Mount Sinai Hospital, Toronto, Ontario, Canada
Botulinum Toxin A to Treat Flexion Contracture After Total Knee Arthroplasty
- Conditions
- Interventions
- First Posted Date
- 2013-04-11
- Last Posted Date
- 2013-12-13
- Lead Sponsor
- Rothman Institute Orthopaedics
- Target Recruit Count
- 140
- Registration Number
- NCT01829087
- Locations
- 🇺🇸
Rothman Institute, Lankenau, Pennsylvania, United States
Botulinum Toxin for Stomach Cancer Treatment
- First Posted Date
- 2013-04-02
- Last Posted Date
- 2018-03-09
- Lead Sponsor
- St. Olavs Hospital
- Target Recruit Count
- 7
- Registration Number
- NCT01822210
- Locations
- 🇳🇴
Department of Gastrointestinal Surgery, St Olavs Hospital Trondheim University Hospital, Trondheim, Norway
Effect of Botox and Vibration on Bone in Children With Cerebral Palsy
- Conditions
- Interventions
- First Posted Date
- 2013-03-04
- Last Posted Date
- 2018-03-20
- Lead Sponsor
- University of Delaware
- Target Recruit Count
- 29
- Registration Number
- NCT01803464
- Locations
- 🇺🇸
University of Delaware, Newark, Delaware, United States
🇺🇸Alfred I. duPont Hospital for Children, Nemours, Wilmington, Delaware, United States
Phase IV Study On Muscle Activity Of Two Commercial Preparations Of Botulinum
- First Posted Date
- 2012-11-19
- Last Posted Date
- 2019-07-26
- Lead Sponsor
- Brazilan Center for Studies in Dermatology
- Target Recruit Count
- 80
- Registration Number
- NCT01728337
- Locations
- 🇧🇷
Brazilian Center For Studies in Dermatology, Porto Alegre, RS, Brazil
Treatment of Plantar Fasciitis With Xeomin
- First Posted Date
- 2012-09-03
- Last Posted Date
- 2017-01-18
- Lead Sponsor
- Rothman Institute Orthopaedics
- Target Recruit Count
- 50
- Registration Number
- NCT01678001
- Locations
- 🇺🇸
Rothman Institute Orthopaedics, Philadelphia, Pennsylvania, United States
Intraprostatic Botulinum Toxin Type "A" Injection in Patients With Benign Prostatic Hyperplasia and Unsatisfactory Response to Medical Therapy
- Conditions
- Interventions
- First Posted Date
- 2012-03-29
- Last Posted Date
- 2012-03-29
- Lead Sponsor
- Catholic University of the Sacred Heart
- Target Recruit Count
- 33
- Registration Number
- NCT01566292
- Locations
- 🇮🇹
Catholic University of Sacred Heart, Rome, Italy
Efficacy Study of Botox for Depression
- First Posted Date
- 2012-03-19
- Last Posted Date
- 2012-03-19
- Lead Sponsor
- Capital Clinical Research Associates, LLC
- Target Recruit Count
- 60
- Registration Number
- NCT01556971
- Locations
- 🇺🇸
Capital Clinical Research Associates, LLC, Rockville, Maryland, United States
🇺🇸Chevy Chase Cosmetic Center, Chevy Chase, Maryland, United States
Drug Development Updates
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