Apraglutide

Generic Name
Apraglutide
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
1295353-98-8
Unique Ingredient Identifier
CVQ1IAY2G6
Associated Conditions
-
Associated Therapies
-

Relative Bioavailability of a New Presentation of Apraglutide Versus the Reference Formulation

Phase 1
Completed
Conditions
Interventions
First Posted Date
2023-08-21
Last Posted Date
2024-10-26
Lead Sponsor
VectivBio AG
Target Recruit Count
34
Registration Number
NCT06002555
Locations
🇳🇱

ICON Clinical Research Unit, Groningen, Netherlands

Evaluation of Apraglutide on Gastric Emptying

First Posted Date
2023-08-16
Last Posted Date
2024-10-24
Lead Sponsor
VectivBio AG
Target Recruit Count
42
Registration Number
NCT05995704
Locations
🇳🇱

ICON Clinical Research Unit, Groningen, Netherlands

A Phase 1, Open-Label Evaluation of the Pharmacokinetics and Safety of a Single Dose of Apraglutide in Subjects With Normal and Impaired Hepatic Function

Phase 1
Completed
Conditions
Interventions
First Posted Date
2023-01-31
Last Posted Date
2024-10-24
Lead Sponsor
VectivBio AG
Target Recruit Count
16
Registration Number
NCT05706623
Locations
🇩🇪

APEX, Münich, Germany

🇸🇰

Summit Clinical Research, Bratislava, Slovakia

Proof-of-concept Trial of Apraglutide in GVHD

Phase 2
Active, not recruiting
Conditions
Interventions
First Posted Date
2022-06-13
Last Posted Date
2024-10-24
Lead Sponsor
VectivBio AG
Target Recruit Count
31
Registration Number
NCT05415410
Locations
🇺🇸

The Ohio State University, Columbus, Ohio, United States

🇩🇪

Universitätsmedizin der Johannes Gutenberg - Universität Mainz, Mainz, Germany

🇩🇪

Universitaetsklinikum Duesseldorf, Düsseldorf, Germany

and more 10 locations

Open-label Extension Trial to Evaluate the Long-term Safety of Apraglutide in Short Bowel Syndrome.

Phase 3
Active, not recruiting
Conditions
Interventions
First Posted Date
2021-08-24
Last Posted Date
2024-10-24
Lead Sponsor
VectivBio AG
Target Recruit Count
158
Registration Number
NCT05018286
Locations
🇯🇵

Yokohama Municipal Citizen's Hospital, Kanagawa, Japan

🇺🇸

Ronald Reagan UCLA Medical Center, Los Angeles, California, United States

🇺🇸

Gastroenterology Group of Naples, Naples, Florida, United States

and more 63 locations

Metabolic Balance Study of Apraglutide in Patients With SBS-IF and Colon-in-Continuity

Phase 2
Completed
Conditions
Interventions
First Posted Date
2021-07-16
Last Posted Date
2024-10-24
Lead Sponsor
VectivBio AG
Target Recruit Count
9
Registration Number
NCT04964986
Locations
🇫🇷

Beaujon Hospital, Clichy, France

🇧🇪

UZ Leuven, Leuven, Belgium

Study of Pharmacokinetics and Safety of Apraglutide in Participants With Normal and Impaired Kidney Function.

Phase 1
Completed
Conditions
Interventions
First Posted Date
2021-01-07
Last Posted Date
2024-10-26
Lead Sponsor
VectivBio AG
Target Recruit Count
16
Registration Number
NCT04699032
Locations
🇺🇸

Prism Clinical Research, Inc., Saint Paul, Minnesota, United States

🇺🇸

Orlando Clinical Research Center, Orlando, Florida, United States

Trial to Evaluate Efficacy and Safety of Apraglutide in SBS-IF

Phase 3
Completed
Conditions
Interventions
First Posted Date
2020-11-13
Last Posted Date
2024-11-27
Lead Sponsor
VectivBio AG
Target Recruit Count
164
Registration Number
NCT04627025
Locations
🇭🇺

University of Szeged, Szeged, Hungary

🇺🇸

Duke University Hospital, Durham, North Carolina, United States

🇩🇰

Rigshospitalet - University Hospital Copenhagen, Copenhagen, Denmark

and more 65 locations
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