Camrelizumab

Generic Name
Camrelizumab
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
1798286-48-2
Unique Ingredient Identifier
73096E137E
Background

Camrelizumab is under investigation in clinical trial NCT03417895 (SHR-1210 Combined With Apatinib in Treatment of ED-SCLC After Failure of First Line Standard Therapy).

Indication

⑴用于至少经过二线系统化疗的复发或难治性经典型霍奇金淋巴瘤患者的治疗。

⑵用于霍奇金淋巴瘤(三线)、肝细胞癌(二线)、非鳞状非小细胞肺癌(一线联合)、食管鳞癌(二线)。

⑶用于既往接受过二线及以上化疗后疾病进展或不可耐受的晚期鼻咽癌患者的治疗。

⑷联合顺铂和吉西他滨用于局部复发或转移性鼻咽癌患者的一线治疗。

Associated Conditions
-
Associated Therapies
-

SHR-1210 in Recurrent/Metastatic Nasopharyngeal Carcinoma Who Have Received Previous At Least Two Lines of Chemotherapy.

Phase 2
Completed
Conditions
Interventions
First Posted Date
2018-06-15
Last Posted Date
2024-03-15
Lead Sponsor
Jiangsu HengRui Medicine Co., Ltd.
Target Recruit Count
156
Registration Number
NCT03558191
Locations
🇨🇳

Cancer Center of Sun-Yat Sen University (CCSYSU), Guangzhou, Guangdong, China

A Trial of SHR-1210 (an Anti-PD-1 Inhibitor) in Combination With Hypofraction Radiotherapy in Patients With NSCLC

Phase 2
Conditions
Interventions
First Posted Date
2018-06-15
Last Posted Date
2020-02-05
Lead Sponsor
Shandong Cancer Hospital and Institute
Target Recruit Count
42
Registration Number
NCT03557411
Locations
🇨🇳

Shandong Cancer Hospital and Institute, Jinan, Shandong, China

Anti-CTLA-4 Antibody Followed by Anti-PD-1 Antibody in Recurrent or Metastatic NSCLC

First Posted Date
2018-05-17
Last Posted Date
2018-05-30
Lead Sponsor
Sun Yat-sen University
Target Recruit Count
10
Registration Number
NCT03527251
Locations
🇨🇳

Cancer Center of Sun-Yat Sen University (CCSYSU), GuangZhou, Guangdong, China

PD-1 Antibody Versus Best Supportive Care After Chemoradiation in Locoregionally Advanced Nasopharyngeal Carcinoma

Phase 3
Active, not recruiting
Conditions
Interventions
First Posted Date
2018-02-09
Last Posted Date
2024-04-09
Lead Sponsor
Sun Yat-sen University
Target Recruit Count
450
Registration Number
NCT03427827
Locations
🇨🇳

Xiangya Hospital Central South University, Changsha, Hunan, China

🇨🇳

First People's Hospital of Foshan, Foshan, Guangdong, China

🇨🇳

Guangzhou Medical University Cancer Hospital, Guangzhou, Guangdong, China

and more 8 locations

SHR-1210 Combined With Apatinib in Treatment of ED-SCLC After Failure of First Line Standard Therapy

Phase 2
Completed
Conditions
Interventions
First Posted Date
2018-01-31
Last Posted Date
2024-08-07
Lead Sponsor
Jiangsu HengRui Medicine Co., Ltd.
Target Recruit Count
59
Registration Number
NCT03417895
Locations
🇨🇳

Cancer Hospital Chinese Academy of Medical Science, Beijing, Beijing, China

🇨🇳

Zhejiang Cancer Hospital, Hangzhou, Zhejiang, China

A Trial of SHR-1210 (an Anti-PD-1 Antibody) in Combination With Apatinib in Patients With Advanced TNBC

Phase 2
Completed
Conditions
Interventions
First Posted Date
2018-01-09
Last Posted Date
2020-10-23
Lead Sponsor
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Target Recruit Count
40
Registration Number
NCT03394287
Locations
🇨🇳

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China

SHR-1210 in Patients With Relapsed or Refractory Extranodal NK/T Cell Lymphoma

First Posted Date
2017-12-06
Last Posted Date
2020-06-18
Lead Sponsor
Jiangsu HengRui Medicine Co., Ltd.
Target Recruit Count
97
Registration Number
NCT03363555
Locations
🇨🇳

First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China

Apatinib Plus Anti-PD1 Therapy for Advanced Osteosarcoma

First Posted Date
2017-12-02
Last Posted Date
2020-05-19
Lead Sponsor
Peking University People's Hospital
Target Recruit Count
43
Registration Number
NCT03359018
Locations
🇨🇳

Musculoskeletal Tumor Center of Peking University People's Hospital, Beijing, China

🇨🇳

Peking University Shougang Hospital, Beijing, China

Two Stage Study of Combination of Chemotherapy, SHR-1210 and/or Decitabine for Relapsed/Refractory PMBCLs

First Posted Date
2017-11-17
Last Posted Date
2018-12-03
Lead Sponsor
Chinese PLA General Hospital
Target Recruit Count
30
Registration Number
NCT03346642
Locations
🇨🇳

Biotherapeutic Department and Pediatrics Department of Chinese PLA General Hospital, Beijing, Beijing, China

🇨🇳

Biotherapeutic Department of Chinese PLA General Hospital, Beijing, Beijing, China

SHR-1210 Alone or in Combination With Decitabine in Relapsed or Refractory Hodgkin Lymphoma

Phase 2
Recruiting
Conditions
Interventions
First Posted Date
2017-08-16
Last Posted Date
2019-04-01
Lead Sponsor
Chinese PLA General Hospital
Target Recruit Count
280
Registration Number
NCT03250962
Locations
🇨🇳

Biotherapeutic Department of Chinese PLA General Hospital, Beijing, Beijing, China

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