Metformin
- Generic Name
- Metformin
- Brand Names
- Actoplus Met, Avandamet, Fortamet, Glucophage, Glucovance, Glumetza, Glycon, Invokamet, Janumet, Jentadueto, Kazano, Kombiglyze, Komboglyze, Qternmet, Riomet, Segluromet, Synjardy, Trijardy, Velmetia, Xigduo
- Drug Type
- Small Molecule
- Chemical Formula
- C4H11N5
- CAS Number
- 657-24-9
- Unique Ingredient Identifier
- 9100L32L2N
- Background
Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.
...
- Indication
Metformin immediate-release formulations
Metformin is indicated as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients ≥10 years old with type 2 diabetes mellitus.
Metformin extended-release tablet (XR)
...
- Associated Conditions
- Cardiovascular Mortality, End Stage Renal Disease (ESRD), Hospitalizations, Polycystic Ovarian Syndrome (PCOS), Type 2 Diabetes Mellitus, Decreased estimated glomerular filtration rate
- Associated Therapies
- -
A Study in Healthy Men to Test Whether Zongertinib Influences the Amount of 4 Other Medicines (Dabigatran, Rosuvastatin, Metformin, and Furosemide) in the Blood
- Conditions
- Interventions
- First Posted Date
- 2024-07-17
- Last Posted Date
- 2024-12-20
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 32
- Registration Number
- NCT06504862
- Locations
- 🇩🇪
Humanpharmakologisches Zentrum Biberach, Biberach, Germany
Serum Biomarker Levels Improvement in Poly Cystic Ovarian Syndrome: Impact of Metformin Compared to Healthy Controls
- Conditions
- Interventions
- First Posted Date
- 2024-06-28
- Last Posted Date
- 2024-06-28
- Lead Sponsor
- Aga Khan University
- Target Recruit Count
- 110
- Registration Number
- NCT06479434
- Locations
- 🇵🇰
DBBS, Karachi, Sind, Pakistan
Metformin as an add-on or Monotherapy in Treatment of Aging People With Multiple Sclerosis (MS)
- First Posted Date
- 2024-06-18
- Last Posted Date
- 2024-10-28
- Lead Sponsor
- State University of New York at Buffalo
- Target Recruit Count
- 30
- Registration Number
- NCT06463743
Preventing T2DM After GDM With Immediate Postpartum Screening
- Conditions
- Interventions
- First Posted Date
- 2024-06-13
- Last Posted Date
- 2024-11-15
- Lead Sponsor
- University of Massachusetts, Worcester
- Target Recruit Count
- 116
- Registration Number
- NCT06457139
- Locations
- 🇺🇸
University of Massachusetts Memorial Medical Center, Worcester, Massachusetts, United States
Preeclampsia Intervention Netherlands
- Conditions
- Interventions
- First Posted Date
- 2024-06-11
- Last Posted Date
- 2024-06-11
- Lead Sponsor
- Amsterdam UMC
- Target Recruit Count
- 180
- Registration Number
- NCT06452498
Comparing the Effect of Metformin vs. Pep2dia as an Adjunct to Letrozole on Ovulation Induction and Pregnancy Outcomes in Overweight Women With PCOS
- First Posted Date
- 2024-06-11
- Last Posted Date
- 2024-08-26
- Lead Sponsor
- Muhamed Ahmed Abdelmoaty Muhamed Alhagrasy
- Target Recruit Count
- 100
- Registration Number
- NCT06452511
- Locations
- 🇪🇬
Al-Hussein University Hospital, Cairo, Egypt
Real-World Evaluation of Omarigliptin for Type 2 Diabetes Meliitus in Bangladesh
- First Posted Date
- 2024-06-07
- Last Posted Date
- 2024-07-16
- Lead Sponsor
- Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders
- Target Recruit Count
- 938
- Registration Number
- NCT06449235
- Locations
- 🇧🇩
BIRDEM General Hospital, Dhaka, Bangladesh
DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment of Gestational Diabetes
- Conditions
- Interventions
- First Posted Date
- 2024-06-06
- Last Posted Date
- 2024-08-09
- Lead Sponsor
- Ohio State University
- Target Recruit Count
- 1572
- Registration Number
- NCT06445946
- Locations
- 🇺🇸
University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States
🇺🇸University of Alabama, Tuscaloosa, Alabama, United States
🇺🇸Wake Forest University, Winston-Salem, North Carolina, United States
Prevention of Progression of Prediabetes, Obesity and CV Risk
- Conditions
- Interventions
- First Posted Date
- 2024-06-06
- Last Posted Date
- 2024-10-17
- Target Recruit Count
- 64
- Registration Number
- NCT06446531
- Locations
- 🇺🇸
University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States
Effects of First-Line Oral Hypoglycemics in Bone Markers of Treatment Naïve Saudi Adults With Type 2 Diabetes
- Conditions
- Interventions
- First Posted Date
- 2024-06-03
- Last Posted Date
- 2024-06-03
- Lead Sponsor
- King Saud University
- Target Recruit Count
- 111
- Registration Number
- NCT06439758
Drug Development Updates
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