Metformin
- Generic Name
- Metformin
- Brand Names
- Actoplus Met, Avandamet, Fortamet, Glucophage, Glucovance, Glumetza, Glycon, Invokamet, Janumet, Jentadueto, Kazano, Kombiglyze, Komboglyze, Qternmet, Riomet, Segluromet, Synjardy, Trijardy, Velmetia, Xigduo
- Drug Type
- Small Molecule
- Chemical Formula
- C4H11N5
- CAS Number
- 657-24-9
- Unique Ingredient Identifier
- 9100L32L2N
- Background
Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.
...
- Indication
Metformin immediate-release formulations
Metformin is indicated as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients ≥10 years old with type 2 diabetes mellitus.
Metformin extended-release tablet (XR)
...
- Associated Conditions
- Cardiovascular Mortality, End Stage Renal Disease (ESRD), Hospitalizations, Polycystic Ovarian Syndrome (PCOS), Type 2 Diabetes Mellitus, Decreased estimated glomerular filtration rate
- Associated Therapies
- -
Liraglutide Treatment in Obese Infertile PCOS Women
- Conditions
- Interventions
- First Posted Date
- 2024-12-19
- Last Posted Date
- 2024-12-19
- Lead Sponsor
- Peking University Third Hospital
- Target Recruit Count
- 890
- Registration Number
- NCT06742710
Impact of Metformin in Rectal Cancer Patients
- First Posted Date
- 2024-12-11
- Last Posted Date
- 2024-12-16
- Lead Sponsor
- Minia University
- Target Recruit Count
- 85
- Registration Number
- NCT06728982
- Locations
- 🇪🇬
Minia Oncology Center, Minya, Egypt
🇪🇬Minia University Hospital, Minya, Egypt
Influence of HRS9531 on Gastric Emptying and Pharmacokinetics of Metformin, Atorvastatin, Warfarin, and Digoxin in Healthy Subjects
- Conditions
- Interventions
- First Posted Date
- 2024-12-09
- Last Posted Date
- 2024-12-09
- Lead Sponsor
- Fujian Shengdi Pharmaceutical Co., Ltd.
- Target Recruit Count
- 57
- Registration Number
- NCT06723691
- Locations
- 🇨🇳
The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China
Efficacy of Metformin as an Adjunct to Standard Antidepressant Therapy in Treating Depression Among Obese Patients
- First Posted Date
- 2024-11-27
- Last Posted Date
- 2024-11-28
- Lead Sponsor
- Fazaia Ruth Pfau Medical College
- Target Recruit Count
- 140
- Registration Number
- NCT06707012
- Locations
- 🇵🇰
Fazaia Rurh Pfau Medical College, Karachi, Sindh, Pakistan
🇵🇰Fazaia Ruth Pfau Medical College, Karachi, Sindh, Pakistan
Efficacy and Safety of Platelet-rich Plasma, Metformin and Cryotherapy in Treatment of Non-genital Warts
- Conditions
- Interventions
- First Posted Date
- 2024-11-15
- Last Posted Date
- 2024-11-15
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 108
- Registration Number
- NCT06691542
Metformin as a Metabolic Intervention in Oesophageal Adenocarcinomas to Improve Response to Neoadjuvant Chemoradiotherapy
- Conditions
- Interventions
- First Posted Date
- 2024-11-14
- Last Posted Date
- 2024-11-18
- Lead Sponsor
- Amsterdam UMC, location VUmc
- Target Recruit Count
- 14
- Registration Number
- NCT06687876
- Locations
- 🇳🇱
Amsterdam UMC, Amsterdam, Netherlands
Effects of Metformin on Hepatic Venous Pressure Gradient in Patients with Cirrhosis and Portal Hypertension
- Conditions
- Interventions
- First Posted Date
- 2024-11-13
- Last Posted Date
- 2024-11-13
- Lead Sponsor
- Assistance Publique - Hôpitaux de Paris
- Target Recruit Count
- 76
- Registration Number
- NCT06687265
Heterogeneity of Diabetes: Integrated Muli-Omics to Identify Physiologic Subphenotypes and Evaluate Targeted Prevention
- Conditions
- Interventions
- First Posted Date
- 2024-11-11
- Last Posted Date
- 2024-11-11
- Lead Sponsor
- Stanford University
- Target Recruit Count
- 200
- Registration Number
- NCT06682351
- Locations
- 🇺🇸
Stanford University, Stanford, California, United States
A Study to Assess Drug-drug Interaction of ZX008 in Healthy Male and Female Study Participants
- Conditions
- Interventions
- First Posted Date
- 2024-11-07
- Last Posted Date
- 2024-12-13
- Lead Sponsor
- UCB BIOSCIENCES, Inc.
- Target Recruit Count
- 22
- Registration Number
- NCT06679413
- Locations
- 🇺🇸
Up0132 1001, Baltimore, Maryland, United States
Study of Time-restricted Eating (TRE) to Clinical Pregnancy Rate in PCOS Women With Glucose Metabolism Disorder Via IVF/ICSI
- Conditions
- Interventions
- First Posted Date
- 2024-10-31
- Last Posted Date
- 2024-10-31
- Lead Sponsor
- RenJi Hospital
- Target Recruit Count
- 254
- Registration Number
- NCT06666933
- Locations
- 🇨🇳
RenJi Hospital Department of Endocrinology and Metabolism, Shanghai, Shanghai, China
Drug Development Updates
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