Adefovir dipivoxil
- Generic Name
- Adefovir dipivoxil
- Brand Names
- Hepsera
- Drug Type
- Small Molecule
- Chemical Formula
- C20H32N5O8P
- CAS Number
- 142340-99-6
- Unique Ingredient Identifier
- U6Q8Z01514
- Background
Adefovir dipivoxil, previously called bis-POM PMEA, with trade names Preveon and Hepsera, is an orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) used for treatment of hepatitis B. It is ineffective against HIV-1. Adefovir dipivoxil is the diester prodrug of adefovir.
- Indication
Indicated for the treatment of chronic hepatitis B in adult patients with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease; this is based on histological, virological, biochemical, and serological responses in adult patients with HBeAg+ and HBeAg- chroni...
- Associated Conditions
- Chronic Hepatitis B Infection
- Associated Therapies
- -
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