Aminoglutethimide
- Generic Name
- Aminoglutethimide
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16N2O2
- CAS Number
- 125-84-8
- Unique Ingredient Identifier
- 0O54ZQ14I9
- Background
An aromatase inhibitor that produces a state of "medical" adrenalectomy by blocking the production of adrenal steroids. It also blocks the conversion of androgens to estrogens. Aminoglutethimide has been used in the treatment of advanced breast and prostate cancer. It was formerly used for its weak anticonvulsant properties. (From Martindale, The Extra Pharm...
- Indication
For the suppression of adrenal function in selected patients with Cushing's syndrome, malignant neoplasm of the female breast, and carcinoma in situ of the breast.
- Associated Conditions
- -
- Associated Therapies
- -
A Phase II Trial of Early Medical Adrenalectomy for "D0.5" Prostate Cancer
Phase 2
Terminated
- Conditions
- Interventions
- First Posted Date
- 2004-04-02
- Last Posted Date
- 2012-09-27
- Target Recruit Count
- 2
- Registration Number
- NCT00006371
- Locations
- 🇺🇸
H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States
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