Coenzyme M

Generic Name
Coenzyme M
Brand Names
Uromitexan
Drug Type
Small Molecule
Chemical Formula
C2H6O3S2
CAS Number
3375-50-6
Unique Ingredient Identifier
VHD28S0H7F
Background

Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.

Indication

Mesna is a uroprotective agent and is used prophylactically to reduce ifosfamide and cyclophosphamide induced hemorrhagic cystitis.

Associated Conditions
Hemorrhagic cystitis caused by cyclophosphamide, Hemorrhagic cystitis caused by ifosfamide
Associated Therapies
-

Effects of Mesna on Homocysteine in Kidney Failure

Phase 2
Completed
Conditions
Interventions
First Posted Date
2007-09-03
Last Posted Date
2018-11-06
Lead Sponsor
Lawson Health Research Institute
Target Recruit Count
10
Registration Number
NCT00524199
Locations
🇨🇦

London Health Sciences Centre, London, Ontario, Canada

R-MACLO-IVAM and Thalidomide in Untreated Mantle Cell Lymphoma

First Posted Date
2007-03-22
Last Posted Date
2015-11-10
Lead Sponsor
University of Miami
Target Recruit Count
22
Registration Number
NCT00450801
Locations
🇺🇸

University of Miami Sylvester Comprehensive Cancer Center - Miami, Miami, Florida, United States

Velcade Plus ICE for Patients With Relapsed Classical Hodgkin Lymphoma

First Posted Date
2007-02-23
Last Posted Date
2012-07-09
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
14
Registration Number
NCT00439361
Locations
🇺🇸

UT MD Anderson Cancer Center, Houston, Texas, United States

Autologous Peripheral Blood Stem Cell Transplant for Germ Cell Tumors

First Posted Date
2007-02-07
Last Posted Date
2022-05-17
Lead Sponsor
Masonic Cancer Center, University of Minnesota
Target Recruit Count
23
Registration Number
NCT00432094
Locations
🇺🇸

Masonic Cancer Center at University of Minnesota, Minneapolis, Minnesota, United States

Hematopoietic Stem Cell Therapy for Patients With Refractory Myasthenia Gravis

First Posted Date
2007-01-19
Last Posted Date
2018-08-31
Lead Sponsor
Northwestern University
Target Recruit Count
9
Registration Number
NCT00424489
Locations
🇺🇸

Northwestern University, Feinberg School of Medicine, Chicago, Illinois, United States

Palonosetron in Sarcoma Patients Receiving Chemotherapy With Adriamycin and Ifosfamide (AI)

First Posted Date
2006-12-13
Last Posted Date
2013-03-22
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
51
Registration Number
NCT00410488
Locations
🇺🇸

UT MD Anderson Cancer Center, Houston, Texas, United States

Lymphodepletion Plus Adoptive Cell Transfer with or Without Dendritic Cell Immunization in Patients with Metastatic Melanoma

First Posted Date
2006-06-20
Last Posted Date
2024-10-21
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
1230
Registration Number
NCT00338377
Locations
🇺🇸

The University of Texas MD Anderson Cancer Center, Houston, Texas, United States

Efficacy of the HCVIDDOXIL Regimen in Patients With Newly Diagnosed Peripheral T-Cell Lymphoma

First Posted Date
2006-02-13
Last Posted Date
2020-09-23
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
55
Registration Number
NCT00290433
Locations
🇺🇸

University of Texas MD Anderson Cancer Center, Houston, Texas, United States

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