Zolpidem

Generic Name
Zolpidem
Brand Names
Ambien, Edluar, Intermezzo, Tovalt
Drug Type
Small Molecule
Chemical Formula
C19H21N3O
CAS Number
82626-48-0
Unique Ingredient Identifier
7K383OQI23
Background

Zolpidem, also known as Ambien, is a hypnotic drug that was initially approved by the FDA in 1992 . Zolpidem improves sleep in patients with insomnia. It is aimed for use in patients with difficulties initiating sleep. This drug decreases the time to fall asleep (sleep latency), increases the duration of sleep, and decreases the number of awakenings during s...

Indication

This drug is indicated for the short-term treatment of insomnia in adults characterized by difficulties with sleep initiation .

Associated Conditions
Insomnia
Associated Therapies
-
Clinical Trials
Related News

A Study to Evaluate the Efficacy, Safety, and Tolerability of JNJ-42847922 in Participants With Insomnia Disorder

First Posted Date
2017-12-15
Last Posted Date
2024-02-07
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
365
Registration Number
NCT03375203
Locations
🇩🇪

Synexus Clinical Research GmbH, Sachsen, Germany

🇩🇪

Klinische Forschung Schwerin GmbH, Schwerin, Germany

🇯🇵

SOUSEIKAI PS Clinic, Fukuoka-shi, Japan

and more 52 locations

Multimodal Sleep Pathway for Shoulder Arthroplasty

First Posted Date
2017-09-01
Last Posted Date
2020-05-27
Lead Sponsor
University of California, San Francisco
Target Recruit Count
122
Registration Number
NCT03269760
Locations
🇺🇸

Ucsf, San Francisco, California, United States

Zolpidem or Exercise for Insomnia?

Early Phase 1
Completed
Conditions
Chronic Insomnia
Interventions
Behavioral: Exercise
Drug: Zolpidem
First Posted Date
2017-05-19
Last Posted Date
2021-03-01
Lead Sponsor
Universidade Federal de Goias
Target Recruit Count
34
Registration Number
NCT03160404
Locations
🇧🇷

Hospital Padre Thiago, jATAÍ, GO, Brazil

Z-Drugs for Sleep Disorders in Alzheimer's Disease

First Posted Date
2017-03-09
Last Posted Date
2020-11-10
Lead Sponsor
Brasilia University Hospital
Target Recruit Count
62
Registration Number
NCT03075241
Locations
🇧🇷

Geriatric Medical Centre, Brasilia, Distrito Federal, Brazil

Study to Validate the Questionnaire Called IDSIQ™ in Patients With Insomnia Disorder

Phase 2
Completed
Conditions
Insomnia Disorder
Interventions
Drug: Zolpidem
First Posted Date
2017-02-17
Last Posted Date
2019-07-24
Lead Sponsor
Idorsia Pharmaceuticals Ltd.
Target Recruit Count
113
Registration Number
NCT03056053
Locations
🇺🇸

Santa Monica Clinical Trials, Santa Monica, California, United States

🇺🇸

Neurotrials Research Inc, Atlanta, Georgia, United States

🇩🇪

CTC North, Universitätsklinikum Hamburg- Eppendorf, Hamburg, Germany

and more 6 locations

Efficacy and Safety of ACT-541468 in Adult Subjects With Insomnia Disorder

First Posted Date
2016-07-20
Last Posted Date
2020-04-13
Lead Sponsor
Idorsia Pharmaceuticals Ltd.
Target Recruit Count
360
Registration Number
NCT02839200
Locations
🇸🇪

Investigator Site, Örebro, Sweden

Hypnotic Intake and Motor and Cognitive Performances at High Altitude

Not Applicable
Completed
Conditions
Physiology
Interventions
Drug: Placebo
Drug: Zolpidem
First Posted Date
2016-05-20
Last Posted Date
2018-01-05
Lead Sponsor
Centre d'Expertise sur l'Altitude EXALT
Target Recruit Count
22
Registration Number
NCT02778659
Locations
🇫🇷

Grenoble University Hospital, Grenoble, Rhone Alpes, France

Pilot Study to Evaluate the Duration of Effects on Simulated Car Driving and Cognitive Performance After a Single Dose of JNJ-42847922, Zolpidem and Placebo in Healthy Participants

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: JNJ-42847922
Drug: Zolpidem
Drug: Placebo
First Posted Date
2015-10-19
Last Posted Date
2016-03-24
Lead Sponsor
Janssen-Cilag International NV
Target Recruit Count
36
Registration Number
NCT02578472

The Study of Spectrum of Sleep Disorders in Cirrhotic Patients and the Efficacy of Zolpidem in Cirrhotic Patients With Insomnia

Not Applicable
Completed
Conditions
Cirrhosis
Interventions
Drug: placebo
Drug: Zolpidem
First Posted Date
2015-06-30
Last Posted Date
2018-05-17
Lead Sponsor
Institute of Liver and Biliary Sciences, India
Target Recruit Count
52
Registration Number
NCT02484963
Locations
🇮🇳

Institute of Liver and Biliary Sciences, New Delhi, Delhi, India

Pharmacovigilance in Gerontopsychiatric Patients

Phase 3
Terminated
Conditions
Dementia
Depression
Schizophrenia
Psychosomatic Disorders
Anxiety Disorders
Interventions
Drug: Phenobarbital
Drug: Phenytoin
Drug: Carbamazepine
Drug: Oxcarbazepine
Drug: Valproic Acid
Drug: Lamotrigine
Drug: Topiramate
Drug: Gabapentin
Drug: Levetiracetam
Drug: Pregabalin
Drug: Lacosamide
Drug: Clonazepam
Drug: Biperiden
Drug: Levomepromazine
Drug: Fluphenazine
Drug: Perphenazine
Drug: Perazine
Drug: Thioridazine
Drug: Haloperidol
Drug: Melperone
Drug: Pipamperone
Drug: Bromperidol
Drug: Benperidol
Drug: Sertindole
Drug: Ziprasidone
Drug: Flupentixol
Drug: Chlorprothixene
Drug: Zuclopenthixol
Drug: Fluspirilene
Drug: Pimozide
Drug: Clozapine
Drug: Olanzapine
Drug: Quetiapine
Drug: Sulpiride
Drug: Tiapride
Drug: Amisulpride
Drug: Prothipendyl
Drug: Risperidone
Drug: Aripiprazole
Drug: Paliperidone
Drug: Diazepam
Drug: Oxazepam
Drug: Lorazepam
Drug: Bromazepam
Drug: Clobazam
Drug: Alprazolam
Drug: Hydroxyzine
Drug: Buspirone
Drug: Chloral Hydrate
Drug: Flurazepam
Drug: Nitrazepam
Drug: Triazolam
Drug: Lormetazepam
Drug: Temazepam
Drug: Midazolam
Drug: Brotizolam
Drug: Zopiclone
Drug: Zolpidem
Drug: Zaleplon
Drug: Melatonin
Drug: Clomethiazole
Drug: Diphenhydramine
Drug: Promethazine
Drug: Imipramine
Drug: Clomipramine
Drug: Opipramol
Drug: Trimipramine
Drug: Amitriptyline
Drug: Nortriptyline
Drug: Doxepin
Drug: Maprotiline
Drug: Amitriptyline oxide
Drug: Fluoxetine
Drug: Citalopram
Drug: Paroxetine
Drug: Sertraline
Drug: Fluvoxamine
Drug: Escitalopram
Drug: Tranylcypromine
Drug: Moclobemide
Drug: Mianserin
Drug: Trazodone
Drug: Mirtazapine
Drug: Bupropion
Drug: Venlafaxine
Drug: Reboxetine
Drug: Duloxetine
Drug: Agomelatine
Drug: Pyritinol
Drug: Piracetam
Drug: Donepezil
Drug: Rivastigmine
Drug: Galantamine
Drug: Memantine
Drug: Nicergoline
Drug: Acamprosate
Drug: Lithium
First Posted Date
2015-03-02
Last Posted Date
2018-02-28
Lead Sponsor
Hannover Medical School
Target Recruit Count
407
Registration Number
NCT02374567
Locations
🇩🇪

Bezirkskrankenhaus Augsburg, Augsburg, Germany

🇩🇪

Krankenhaus Hedwigshöhe, Berlin, Germany

🇩🇪

Hannover Medical School, Hannover, Germany

and more 2 locations
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