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BGB-21447

Generic Name
BGB-21447

BGB-21447 (Bcl-2 Inhibitor) Combinations for Adults With Hormone-Receptor Positive (HR+)/Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Metastatic Breast Cancer

Phase 1
Recruiting
Conditions
Hormone-receptor-positive Breast Cancer
HER2-negative Breast Cancer
Metastatic Breast Cancer
Interventions
First Posted Date
2025-01-03
Last Posted Date
2025-05-09
Lead Sponsor
BeiGene
Target Recruit Count
92
Registration Number
NCT06756932
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Hoag Memorial Presbyterian, Newport Beach, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States

๐Ÿ‡บ๐Ÿ‡ธ

Md Anderson Cancer Center, Houston, Texas, United States

and more 12 locations

A Study of BGB-21447, a Bcl-2 Inhibitor, in Mature B-Cell Malignancies

Phase 1
Recruiting
Conditions
Refractory Chronic Lymphocytic Leukemia
Relapsed Non-Hodgkin Lymphoma
Refractory Non-Hodgkin Lymphoma
Relapsed Chronic Lymphocytic Leukemia
Relapsed Follicular Lymphoma
Relapsed Marginal Zone Lymphoma
Relapse Diffuse Large B Cell Lymphoma
Relapsed Small Lymphocytic Lymphoma
Refractory Follicular Lymphoma
Refractory Marginal Zone Lymphoma
Interventions
First Posted Date
2023-04-25
Last Posted Date
2025-05-20
Lead Sponsor
BeiGene
Target Recruit Count
112
Registration Number
NCT05828589
Locations
๐Ÿ‡ฆ๐Ÿ‡บ

Pindara Private Hospital, Benowa, Queensland, Australia

๐Ÿ‡บ๐Ÿ‡ธ

Mission Cancer and Blood, Waukee, Iowa, United States

๐Ÿ‡บ๐Ÿ‡ธ

Sidney Kimmel Comprehensive Cancer At Johns Hopkins, Baltimore, Maryland, United States

and more 19 locations
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