Pyridoxine

Generic Name
Pyridoxine
Brand Names
Alertonic, Animi-3 With Vitamin D, Bonjesta, Citranatal B-calm Kit, Citranatal Harmony, Concept Ob, Diclectin, Diclegis, Folbic, Foltabs, Fortaplex, Infuvite, Infuvite Pediatric, Irospan 24/6 Kit, Isotamine B, Mvc-fluoride, Mvi Pediatric, Natafort, Neo-bex, Pregvit, Tandem Plus, Vitafol-one
Drug Type
Small Molecule
Chemical Formula
C8H11NO3
CAS Number
65-23-6
Unique Ingredient Identifier
KV2JZ1BI6Z
Background

Pyridoxine is the 4-methanol form of vitamin B6, an important water-soluble vitamin that is naturally present in many foods. As its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required for normal functioning of many biological systems within the body. While many plants and microorganisms are able to synthesize pyr...

Indication

Pyridoxine is indicated for the treatment of vitamin B6 deficiency and for the prophylaxis of Isoniazid-induced peripheral neuropathy. It is also approved by Health Canada for the treatment of nausea and vomiting in pregnancy in a combination product with Doxylamine (as the commercially available product Diclectin).

Associated Conditions
Back pain, Dizziness, Fever, Headache, Hepatic; Functional Disturbance, Hepatitis, Iron Deficiency Anemia (IDA), Ketosis, Macrocytic anemia, Menière's Disease, Menstrual Distress (Dysmenorrhea), Metabolic Acidosis, Motion Sickness, Myalgia, Nausea and vomiting, Neuralgia, Sciatic, Neuritis, Neurological Conditions caused by B Vitamin Deficiency, Secondary anemia, Toothache, Toxinfectious state, Trigeminal Neuralgia (TN), Vitamin B1 deficiency, Vitamin B12 Deficiency, Vitamin B6 Deficiency, Vitamin Deficiency, Minor aches and pains, Minor pain
Associated Therapies
Nutritional supplementation, Supplementation, Vitamin supplementation, Wellness of the Liver

Cervical Ripening Before Endometrial Biopsy in Abnormal Uterine Bleeding Using Sublingual Misoprostol

First Posted Date
2013-01-07
Last Posted Date
2013-01-07
Lead Sponsor
Mahidol University
Target Recruit Count
52
Registration Number
NCT01762319
Locations
🇹🇭

Faculty of Medicine Siriraj Hospital Mahidol University, Bangkok, Thailand

Treatment of Nodding Syndrome - A Randomized Blinded Placebo-Controlled Crossover Trial of Oral Pyridoxine and Conventional Anti-Epileptic Therapy, in Northern Uganda - 2012

First Posted Date
2012-11-21
Last Posted Date
2022-05-18
Lead Sponsor
Centers for Disease Control and Prevention
Registration Number
NCT01730313
Locations
🇺🇬

Kitgum Nodding Syndrome Treatment Center, Kitgum General Hospital, Kitgum, Uganda

Rifampin-Based Tuberculosis Treatment Versus Rifabutin-Based Tuberculosis Treatment in Persons With HIV

First Posted Date
2012-05-18
Last Posted Date
2018-02-13
Lead Sponsor
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Target Recruit Count
71
Registration Number
NCT01601626
Locations
🇵🇪

Asociacion Civil Impacta Salud y Educacion - Miraf CRS (11301), Lima, Peru

🇧🇷

Instituto de Pesquisa Clinica Evandro Chagas (12101), Rio de Janeiro, Brazil

🇭🇹

Les Centres GHESKIO CRS (30022), Port-au-Prince, Haiti

and more 6 locations

Modafinil in Cancer Related Fatigue

First Posted Date
2011-09-26
Last Posted Date
2012-03-23
Lead Sponsor
Indira Gandhi Medical College, Shimla
Target Recruit Count
217
Registration Number
NCT01440621
Locations
🇮🇳

Regional Cancer Centre, Shimla, Himachal Pradesh, India

China Stroke Secondary Prevention Trial

First Posted Date
2011-03-17
Last Posted Date
2014-08-20
Lead Sponsor
Xijing Hospital
Registration Number
NCT01317849
Locations
🇨🇳

Xijing Hosptial, Xi'an, Shanxi, China

Trial on Treatment of Patients With Primary Hyperoxaluria Type I With Pyridoxal-phosphate

Phase 2
Completed
Conditions
Interventions
First Posted Date
2011-01-24
Last Posted Date
2012-10-29
Lead Sponsor
University of Cologne
Target Recruit Count
12
Registration Number
NCT01281878
Locations
🇩🇪

Children´s Hospital University of Cologne, Cologne, NRW, Germany

Preoperative Misoprostol in Reducing Blood Loss in Total Abdominal Hysterectomy (TAH)

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2010-09-10
Last Posted Date
2010-09-10
Lead Sponsor
The University of Hong Kong
Target Recruit Count
77
Registration Number
NCT01199159
Locations
🇭🇰

University of Hong Kong, Hong Kong, Hong Kong

Vitamin B6 Can Prevent Hand and Foot Syndrome in Cancer Patients Capecitabine Chemotherapy

Not Applicable
Terminated
Conditions
Interventions
First Posted Date
2008-10-07
Last Posted Date
2023-06-15
Lead Sponsor
Cook County Health
Target Recruit Count
6
Registration Number
NCT00767689
Locations
🇺🇸

John H stroger Jr hospital of cook county, Chicago, Illinois, United States

B6 Treatment for Nausea and Vomiting in Pregnancy

First Posted Date
2008-10-01
Last Posted Date
2008-12-31
Lead Sponsor
Showa University
Target Recruit Count
150
Registration Number
NCT00763633
Locations
🇮🇩

Dept. Obstetric Gynecology Univ. Indonesia, Jakarta, Indonesia

Study of Pyridoxine for Hand-Foot Syndrome

Phase 3
Completed
Conditions
Interventions
First Posted Date
2007-03-12
Last Posted Date
2014-02-25
Lead Sponsor
Asan Medical Center
Target Recruit Count
389
Registration Number
NCT00446147
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