Pyridoxine
- Generic Name
- Pyridoxine
- Brand Names
- Alertonic, Animi-3 With Vitamin D, Bonjesta, Citranatal B-calm Kit, Citranatal Harmony, Concept Ob, Diclectin, Diclegis, Folbic, Foltabs, Fortaplex, Infuvite, Infuvite Pediatric, Irospan 24/6 Kit, Isotamine B, Mvc-fluoride, Mvi Pediatric, Natafort, Neo-bex, Pregvit, Tandem Plus, Vitafol-one
- Drug Type
- Small Molecule
- Chemical Formula
- C8H11NO3
- CAS Number
- 65-23-6
- Unique Ingredient Identifier
- KV2JZ1BI6Z
- Background
Pyridoxine is the 4-methanol form of vitamin B6, an important water-soluble vitamin that is naturally present in many foods. As its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required for normal functioning of many biological systems within the body. While many plants and microorganisms are able to synthesize pyr...
- Indication
Pyridoxine is indicated for the treatment of vitamin B6 deficiency and for the prophylaxis of Isoniazid-induced peripheral neuropathy. It is also approved by Health Canada for the treatment of nausea and vomiting in pregnancy in a combination product with Doxylamine (as the commercially available product Diclectin).
- Associated Conditions
- Back pain, Dizziness, Fever, Headache, Hepatic; Functional Disturbance, Hepatitis, Iron Deficiency Anemia (IDA), Ketosis, Macrocytic anemia, Menière's Disease, Menstrual Distress (Dysmenorrhea), Metabolic Acidosis, Motion Sickness, Myalgia, Nausea and vomiting, Neuralgia, Sciatic, Neuritis, Neurological Conditions caused by B Vitamin Deficiency, Secondary anemia, Toothache, Toxinfectious state, Trigeminal Neuralgia (TN), Vitamin B1 deficiency, Vitamin B12 Deficiency, Vitamin B6 Deficiency, Vitamin Deficiency, Minor aches and pains, Minor pain
- Associated Therapies
- Nutritional supplementation, Supplementation, Vitamin supplementation, Wellness of the Liver
Pyridoxine, P2 Receptor Antagonism, and ATP-mediated Vasodilation in Young Adults
- First Posted Date
- 2018-11-13
- Last Posted Date
- 2021-07-27
- Lead Sponsor
- Colorado State University
- Target Recruit Count
- 9
- Registration Number
- NCT03738943
- Locations
- 🇺🇸
Human Performance and Clinical Research Laboratory, Fort Collins, Colorado, United States
Panobinostat Combined With High-Dose Gemcitabine/Busulfan/Melphalan With Autologous Stem Cell Transplant for Patients With Refractory/Relapsed Lymphoma
- First Posted Date
- 2016-11-11
- Last Posted Date
- 2017-04-21
- Lead Sponsor
- M.D. Anderson Cancer Center
- Registration Number
- NCT02961816
Effect of Vitamin B on Plasma Neurofilament Light Protein (NFL) in HIV-infected Individuals With Increased Plasma Homocysteine
- First Posted Date
- 2016-05-16
- Last Posted Date
- 2018-01-02
- Lead Sponsor
- Göteborg University
- Target Recruit Count
- 60
- Registration Number
- NCT02773147
- Locations
- 🇸🇪
Department of Infectious Diseases, Sahlgrenska university hospital, Gothenburg, Sweden
Belinostat Combined With Azacitidine/Gemcitabine/Busulfan/Melphalan With Autologous Stem-Cell Transplantation in Refractory or Relapsed Lymphoma
- First Posted Date
- 2016-03-08
- Last Posted Date
- 2016-05-04
- Lead Sponsor
- M.D. Anderson Cancer Center
- Registration Number
- NCT02701673
Lenalidomide Combined With Vorinostat/Gemcitabine/Busulfan/Melphalan With Autologous Stem-Cell Transplantation in Diffuse Large B-Cell Lymphoma of the ABC Subtype
- First Posted Date
- 2015-10-28
- Last Posted Date
- 2019-12-13
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 8
- Registration Number
- NCT02589145
- Locations
- 🇺🇸
University of Texas MD Anderson Cancer Center, Houston, Texas, United States
Carfilzomib/SAHA Combined With High-Dose Gemcitabine/Busulfan/Melphalan With Autologous Stem Cell Transplant in Myeloma
- First Posted Date
- 2014-04-15
- Last Posted Date
- 2014-07-11
- Lead Sponsor
- M.D. Anderson Cancer Center
- Registration Number
- NCT02114502
A Multicenter Trial of the Efficacy and Safety of Diclegis® for Nausea and Vomiting of Pregnancy in Pregnant Adolescents
- First Posted Date
- 2014-01-27
- Last Posted Date
- 2021-11-23
- Lead Sponsor
- Duchesnay Inc.
- Target Recruit Count
- 131
- Registration Number
- NCT02045901
- Locations
- 🇺🇸
Jersey Shore University Medical Center, Neptune, New Jersey, United States
🇺🇸Empire Clinical Research, LLC, Miami Lakes, Florida, United States
🇺🇸Medical Professional CR Center, Miami, Florida, United States
Aza-SAHA-GBM With AutoSCT for Refractory Lymphoma
- First Posted Date
- 2013-11-14
- Last Posted Date
- 2020-01-27
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 61
- Registration Number
- NCT01983969
- Locations
- 🇺🇸
University of Texas MD Anderson Cancer Center, Houston, Texas, United States
Pyridoxal Kinase Activity in Tardive Dyskinesia
- First Posted Date
- 2013-07-25
- Last Posted Date
- 2013-07-25
- Lead Sponsor
- Beersheva Mental Health Center
- Registration Number
- NCT01908452
- Locations
- 🇮🇱
Tirat Carmel Mental Health Center, Haifa, Israel
🇮🇱Be'er Sheva Mental Health Center, Be'er Sheva, Israel
🇮🇱Sha'ar Menashe Mental Health Center, Hadera, Israel
Neurodevelopmental Outcome of Early Dietary Lysine Restriction in Pyridoxine Dependent Epilepsy Patients
- Conditions
- Interventions
- First Posted Date
- 2013-02-20
- Last Posted Date
- 2014-09-30
- Lead Sponsor
- University of British Columbia
- Registration Number
- NCT01795170
- Locations
- 🇺🇸
Seattle Children's Hospital, Seattle, Washington, United States
🇺🇸Children's Hospital Colorado, Aurora, Colorado, United States
🇨🇦BC Children's Hospital, Vancouver, British Columbia, Canada
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.