Apelin
- Generic Name
- Apelin
A Series of Pilot Studies to Evaluate the haemoDynamic and mEtabolic Effects oF apelIn aNd rElaxin
- Conditions
- Cardiovascular DiseasesType 2 Diabetes Mellitus
- Interventions
- Drug: Normal salineDiagnostic Test: VerapamilDiagnostic Test: LN Monomethyl arginine
- First Posted Date
- 2018-02-28
- Last Posted Date
- 2024-02-07
- Target Recruit Count
- 170
- Registration Number
- NCT03449251
- Locations
- 🇬🇧
Addenbrooke's Hospital, Cambridge, Cambridgeshire, United Kingdom
Effect of Apelin on Insulin Sensitivity in Type 2 Diabetic Volunteers
- First Posted Date
- 2016-03-31
- Last Posted Date
- 2017-08-22
- Lead Sponsor
- University Hospital, Toulouse
- Target Recruit Count
- 9
- Registration Number
- NCT02724566
- Locations
- 🇫🇷
University Hospitals of Toulouse (Rangueil), Toulouse, Midi-Pyrénées, France
Effect of Apelin on Insulin Sensitivity: Proof of Concept in Healthy Volunteers
- First Posted Date
- 2014-01-10
- Last Posted Date
- 2019-07-12
- Lead Sponsor
- University Hospital, Toulouse
- Target Recruit Count
- 16
- Registration Number
- NCT02033473
- Locations
- 🇫🇷
University Hospital of Toulouse, Toulouse, France
Effects of Apelin on the Lung Circulation in Pulmonary Hypertension
- Conditions
- Pulmonary Arterial HypertensionHeart Failure
- Interventions
- Drug: Saline (Placebo)
- First Posted Date
- 2011-10-21
- Last Posted Date
- 2013-07-15
- Lead Sponsor
- Golden Jubilee National Hospital
- Target Recruit Count
- 63
- Registration Number
- NCT01457170
- Locations
- 🇬🇧
Royal Infirmary Edinburgh, Edinburgh, United Kingdom
🇬🇧Hammersmith Hospital, London, United Kingdom
🇬🇧Golden Jubilee National Hospital, Glasgow, United Kingdom
Investigating the Inotropic Potential of Apelin
- First Posted Date
- 2010-08-10
- Last Posted Date
- 2024-05-09
- Lead Sponsor
- University of Edinburgh
- Target Recruit Count
- 24
- Registration Number
- NCT01179061
- Locations
- 🇬🇧
Clincial Research Facility, Royal Infirmary of Edinburgh, 51 Little France Cresc, Edinburgh, United Kingdom
🇬🇧Gareth Barnes, Edinburgh, United Kingdom
🇬🇧University of Edinburgh, Edinburgh, United Kingdom
Investigating Systemic and Local Vascular Responses to Apelin in the Context of Renin-angiotensin Upregulation
- Conditions
- Heart DiseaseHeart FailureVasodilatation
- Interventions
- First Posted Date
- 2009-05-14
- Last Posted Date
- 2010-08-10
- Lead Sponsor
- University of Edinburgh
- Target Recruit Count
- 12
- Registration Number
- NCT00901719
- Locations
- 🇬🇧
Clincial Research Facility, Royal Infirmary of Edinburgh, 51 Little France Cresc, Edinburgh, United Kingdom
Drug Development Updates
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