Antithymocyte immunoglobulin (rabbit)

Generic Name
Antithymocyte immunoglobulin (rabbit)
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
308067-60-9
Unique Ingredient Identifier
D7RD81HE4W
Background

Rabbit anti-thymocyte globulin. Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients. Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of T-cells.

Indication

For prevention of renal transplant rejection

Associated Conditions
Rejection Acute Renal
Associated Therapies
-

Alloreactive NK Cells for Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS)

First Posted Date
2006-11-22
Last Posted Date
2015-05-08
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
15
Registration Number
NCT00402558
Locations
🇺🇸

UT MD Anderson Cancer Center, Houston, Texas, United States

Simultaneous Pancreas-kidney Transplantation With Campath Protocol

First Posted Date
2006-04-21
Last Posted Date
2012-06-19
Lead Sponsor
Dr. Claudia Bösmüller
Target Recruit Count
30
Registration Number
NCT00316810
Locations
🇦🇹

University Hospital Innsbruck, Innsbruck, Tyrol, Austria

Induction Therapy Study in Live Donor Kidney Transplant Recipients With a Positive Crossmatch

First Posted Date
2006-01-12
Last Posted Date
2018-01-18
Lead Sponsor
Johns Hopkins University
Target Recruit Count
56
Registration Number
NCT00275509
Locations
🇺🇸

The Johns Hopkins University, School of Medicine, Baltimore, Maryland, United States

Single Dose Thymoglobulin for Induction in Adult Renal Allograft Recipients

Not Applicable
Terminated
Conditions
First Posted Date
2005-10-10
Last Posted Date
2006-10-16
Lead Sponsor
Washington University School of Medicine
Target Recruit Count
90
Registration Number
NCT00235781
Locations
🇺🇸

Washington University School of Medicine/Barnes-Jewish Hospital, Saint Louis, Missouri, United States

Stem Cell Transplantation for Hematological Malignancies

First Posted Date
2005-09-15
Last Posted Date
2017-12-05
Lead Sponsor
Masonic Cancer Center, University of Minnesota
Target Recruit Count
11
Registration Number
NCT00176839
Locations
🇺🇸

Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, United States

Study of Unrelated Cord Blood Transplantation Using Tacrolimus and Sirolimus

First Posted Date
2005-08-23
Last Posted Date
2016-07-25
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
32
Registration Number
NCT00133367
Locations
🇺🇸

Dana-Farber Cancer Institute, Boston, Massachusetts, United States

🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

Thymoglobuline in Non-myeloablative Allogeneic Stem-cell Transplantation

First Posted Date
2005-08-16
Last Posted Date
2011-02-23
Lead Sponsor
Hadassah Medical Organization
Target Recruit Count
30
Registration Number
NCT00130754
Locations
🇮🇱

Hadassah Medical Organization, Jerusalem, Israel

Safety and Value of Self Bone Marrow Transplants Following Chemotherapy in Scleroderma Patients

Phase 1
Terminated
Conditions
First Posted Date
2002-07-10
Last Posted Date
2007-12-28
Lead Sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Target Recruit Count
15
Registration Number
NCT00040651
Locations
🇺🇸

UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, United States

High Dose Chemo/Radiotherapy and Hematopoietic Stem Cell Transplant for Patients With Multiple Sclerosis

Phase 2
Completed
Conditions
First Posted Date
2002-06-28
Last Posted Date
2020-01-18
Lead Sponsor
Baylor College of Medicine
Target Recruit Count
10
Registration Number
NCT00040482
Locations
🇺🇸

The Methodist Hospital, Houston, Texas, United States

Megadose CD34 Selected Progenitor Cells for Transplantation in Patients With Advanced Hematological Malignant Diseases

First Posted Date
2002-06-07
Last Posted Date
2012-08-10
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
29
Registration Number
NCT00038857
Locations
🇺🇸

MD Anderson Cancer Center, Houston, Texas, United States

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