Antithymocyte immunoglobulin (rabbit)

Generic Name: Antithymocyte immunoglobulin (rabbit)

Brand Names: -

Drug Type: Biotech

Chemical Formula: -

CAS Number: 308067-60-9

Unique Ingredient Identifier: D7RD81HE4W

Background: Rabbit anti-thymocyte globulin. Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients. Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of T-cells.

Indication: For prevention of renal transplant rejection

Associated Conditions: Rejection Acute Renal

Associated Therapies: -

Clinical Trials

Sirolimus and Thymoglobulin to Prevent Kidney Transplant Rejection

Phase 2

Completed

Conditions: Kidney Failure

Interventions: Drug: Sirolimus
Drug: Thymoglobulin

First Posted Date: 2000-08-16

Last Posted Date: 2019-09-17

Lead Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Target Recruit Count: 12

Registration Number: NCT00006178

Locations: 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

Combination Therapy of Severe Aplastic Anemia

Phase 2

Completed

Conditions: Severe Aplastic Anemia

Interventions: Drug: Cyclosporine A
Drug: ATG
Drug: MMF

First Posted Date: 2000-01-19

Last Posted Date: 2021-03-16

Lead Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Target Recruit Count: 104

Registration Number: NCT00001964

Locations: 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

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