Antithymocyte immunoglobulin (rabbit)

Generic Name
Antithymocyte immunoglobulin (rabbit)
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
308067-60-9
Unique Ingredient Identifier
D7RD81HE4W
Background

Rabbit anti-thymocyte globulin. Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients. Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of T-cells.

Indication

For prevention of renal transplant rejection

Associated Conditions
Rejection Acute Renal
Associated Therapies
-

A Study to Compare the Effectiveness of a Drug That Suppresses the Immune System Called Thymoglobulin® in Preventing the Development of a Disease That Affects the Majority of Heart Transplant Recipients Called Cardiac Allograft Vasculopathy (CAV)

Phase 3
Withdrawn
Conditions
Interventions
First Posted Date
2010-07-08
Last Posted Date
2019-03-14
Lead Sponsor
Cedars-Sinai Medical Center
Registration Number
NCT01157949
Locations
🇺🇸

Cedars-Sinai Medical Center, Beverly Hills, California, United States

Hematopoietic Stem Cell Transplant for Fanconi Anemia

First Posted Date
2010-02-19
Last Posted Date
2019-09-11
Lead Sponsor
Medical College of Wisconsin
Target Recruit Count
1
Registration Number
NCT01071239
Locations
🇺🇸

Medical College of Wisconsin, Milwaukee, Wisconsin, United States

Busulfan Plus Clofarabine Followed by Allogeneic Hematopoietic Stem Cell Transplantation

First Posted Date
2009-10-06
Last Posted Date
2018-08-07
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
120
Registration Number
NCT00990249
Locations
🇺🇸

University of Texas MD Anderson Cancer Center, Houston, Texas, United States

Nonmyeloablative Stem Cell Transplantation for Chronic Lymphocytic Leukemia (CLL)

First Posted Date
2009-05-12
Last Posted Date
2020-01-27
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
39
Registration Number
NCT00899431
Locations
🇺🇸

University of Texas MD Anderson Cancer Center, Houston, Texas, United States

Safety and Efficacy Study of Thymoglobulin Versus IL2 Receptor Antagonists

First Posted Date
2009-03-10
Last Posted Date
2016-04-26
Lead Sponsor
Medical University of South Carolina
Target Recruit Count
200
Registration Number
NCT00859131
Locations
🇺🇸

Medical University of South Carolina, Charleston, South Carolina, United States

Azacitidine After Allo Blood And Marrow Transplantation (BMT) for Chronic Myelogenous Leukemia (CML)

First Posted Date
2008-12-22
Last Posted Date
2021-02-11
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
24
Registration Number
NCT00813124
Locations
🇺🇸

University of Texas MD Anderson Cancer Center, Houston, Texas, United States

Thymoglobulin and Cyclosporine in Patients With Aplastic Anemia or Myelodysplastic Syndrome

First Posted Date
2008-12-11
Last Posted Date
2013-03-12
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
53
Registration Number
NCT00806598
Locations
🇺🇸

UT MD Anderson Cancer Center, Houston, Texas, United States

Hematopoietic Stem Cell Transplant in Devic's Disease

First Posted Date
2008-11-07
Last Posted Date
2020-02-28
Lead Sponsor
Northwestern University
Target Recruit Count
13
Registration Number
NCT00787722
Locations
🇺🇸

Northwestern University, Feinberg School of Medicine, Chicago, Illinois, United States

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