Antithymocyte immunoglobulin (rabbit)

Generic Name
Antithymocyte immunoglobulin (rabbit)
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
308067-60-9
Unique Ingredient Identifier
D7RD81HE4W
Background

Rabbit anti-thymocyte globulin. Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients. Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of T-cells.

Indication

For prevention of renal transplant rejection

Associated Conditions
Rejection Acute Renal
Associated Therapies
-

Autologous Stem Cell Systemic Sclerosis Immune Suppression Trial

First Posted Date
2011-10-04
Last Posted Date
2020-07-23
Lead Sponsor
Northwestern University
Target Recruit Count
44
Registration Number
NCT01445821
Locations
🇺🇸

Northwestern University, Chicago, Illinois, United States

Research Study of ATG and Rituximab in Renal Transplantation

First Posted Date
2011-03-21
Last Posted Date
2018-11-29
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
10
Registration Number
NCT01318915
Locations
🇺🇸

University of California San Francisco Medical Center, San Francisco, California, United States

🇺🇸

University of Maryland Medical Center, Baltimore, Maryland, United States

🇺🇸

Rogosin Institute/New York Presbyterian-Cornell, New York, New York, United States

and more 3 locations

Low Dose Thymoglobin in Renal Transplant Patients

First Posted Date
2011-01-21
Last Posted Date
2021-03-16
Lead Sponsor
Lahey Clinic
Target Recruit Count
44
Registration Number
NCT01280617
Locations
🇺🇸

Lahey Clinic, Burlington, Massachusetts, United States

A Reduced Toxicity Allogeneic Unrelated Donor Stem Cell Transplantation (SCT) for Severe Sickle Cell Disease

First Posted Date
2011-01-19
Last Posted Date
2019-04-03
Lead Sponsor
Nationwide Children's Hospital
Target Recruit Count
8
Registration Number
NCT01279616
Locations
🇺🇸

Nationwide Children's Hospital, Columbus, Ohio, United States

Randomized Trial of 2 Antibody Induction Steroid Avoidance Protocols

First Posted Date
2010-07-29
Last Posted Date
2023-09-28
Lead Sponsor
University of Miami
Target Recruit Count
200
Registration Number
NCT01172418
Locations
🇺🇸

University of Miami Miller School of Medicine, Miami, Florida, United States

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