Antithymocyte immunoglobulin (rabbit)

Generic Name
Antithymocyte immunoglobulin (rabbit)
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
308067-60-9
Unique Ingredient Identifier
D7RD81HE4W
Background

Rabbit anti-thymocyte globulin. Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients. Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of T-cells.

Indication

For prevention of renal transplant rejection

Associated Conditions
Rejection Acute Renal
Associated Therapies
-

Thymoglobulin in Cadaver Donor

First Posted Date
2013-09-11
Last Posted Date
2013-09-11
Lead Sponsor
Instituto de Investigación Hospital Universitario La Paz
Target Recruit Count
20
Registration Number
NCT01939171
Locations
🇵🇹

Hospital Santa Maria, Lisbon, Portugal

🇪🇸

Hospital Universitario La Paz, Madrid, Spain

ATG in Haploidentical HSCT for Acute Graft-versus-host Disease Prophylaxis

First Posted Date
2013-06-21
Last Posted Date
2018-04-24
Lead Sponsor
Nanfang Hospital, Southern Medical University
Target Recruit Count
412
Registration Number
NCT01883180
Locations
🇨🇳

Department of Hematology,Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China

Non-Myeloablative Conditioning and Bone Marrow Transplantation

First Posted Date
2013-05-09
Last Posted Date
2024-01-10
Lead Sponsor
Vanderbilt-Ingram Cancer Center
Target Recruit Count
26
Registration Number
NCT01850108
Locations
🇺🇸

Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, United States

🇫🇷

Saint-Louis Hospital, Paris, France

🇬🇧

St Mary's Hospital, London, United Kingdom

Randomised Study Comparing Different Dosages of Rabbit ATG in Patients With SAA

Phase 3
Conditions
Interventions
First Posted Date
2013-05-01
Last Posted Date
2016-04-01
Lead Sponsor
Nagoya University
Target Recruit Count
320
Registration Number
NCT01844635
Locations
🇯🇵

Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan

Targeting the IPA and Matching for the Non-Inherited Maternal Antigen for Haplo-Cord Transplantation

First Posted Date
2013-03-13
Last Posted Date
2024-10-09
Lead Sponsor
Weill Medical College of Cornell University
Target Recruit Count
270
Registration Number
NCT01810588
Locations
🇺🇸

Weill Cornell Medical College, New York, New York, United States

🇺🇸

University of Chicago Medical Center, Chicago, Illinois, United States

Belatacept Early Steroid Withdrawal Trial

First Posted Date
2012-11-20
Last Posted Date
2021-07-28
Lead Sponsor
University of Cincinnati
Target Recruit Count
316
Registration Number
NCT01729494
Locations
🇺🇸

University of Wisconsin-Madison, Madison, Wisconsin, United States

🇺🇸

Tampa General Hospital, Tampa, Florida, United States

🇺🇸

The Christ Hospital, Cincinnati, Ohio, United States

and more 5 locations

Conditioning Treatment With Umbilical Cord Blood Transplant for Hematologic Malignancies

First Posted Date
2012-06-19
Last Posted Date
2014-02-11
Lead Sponsor
University of Virginia
Target Recruit Count
6
Registration Number
NCT01622556
Locations
🇺🇸

University of Virginia, Charlottesville, Virginia, United States

Fludarabine Based Conditioning for Allogeneic Transplantation for Advanced Hematologic Malignancies

First Posted Date
2011-12-26
Last Posted Date
2018-11-08
Lead Sponsor
University of Illinois at Chicago
Target Recruit Count
100
Registration Number
NCT01499147
Locations
🇺🇸

University of Illinois at Chicago Medical Center, Chicago, Illinois, United States

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