Antithymocyte immunoglobulin (rabbit)

Generic Name
Antithymocyte immunoglobulin (rabbit)
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
308067-60-9
Unique Ingredient Identifier
D7RD81HE4W
Background

Rabbit anti-thymocyte globulin. Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients. Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of T-cells.

Indication

For prevention of renal transplant rejection

Associated Conditions
Rejection Acute Renal
Associated Therapies
-

Stem Cell Transplantation for Stiff Person Syndrome (SPS)

First Posted Date
2014-11-04
Last Posted Date
2021-01-27
Lead Sponsor
Northwestern University
Target Recruit Count
23
Registration Number
NCT02282514
Locations
🇺🇸

Northwestern University, Chicago, Illinois, United States

Transplantation of Partially Mismatched Related or Matched Unrelated Bone Marrow for Patients With Refractory Severe Aplastic Anemia

First Posted Date
2014-08-25
Last Posted Date
2023-03-10
Lead Sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Target Recruit Count
18
Registration Number
NCT02224872
Locations
🇺🇸

The Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, United States

🇺🇸

Medical College of Wisconsin/Children's Hospital of Wisconsin, Milwaukee, Wisconsin, United States

Belatacept Compared to Tacrolimus in Deceased Donor Renal Transplant Recipients

First Posted Date
2014-06-02
Last Posted Date
2021-02-10
Lead Sponsor
Columbia University
Target Recruit Count
57
Registration Number
NCT02152345
Locations
🇺🇸

Columbia University Medical Center, New York, New York, United States

HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy

First Posted Date
2014-05-21
Last Posted Date
2024-12-12
Lead Sponsor
Children's Hospital Medical Center, Cincinnati
Target Recruit Count
70
Registration Number
NCT02143830
Locations
🇺🇸

Fred Hutchinson Cancer Research Center, Seattle, Washington, United States

🇺🇸

Memorial Sloan Kettering Cancer Center, New York, New York, United States

🇺🇸

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States

Regimen Optimization Study

First Posted Date
2014-05-13
Last Posted Date
2021-06-22
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
58
Registration Number
NCT02137239
Locations
🇺🇸

Emory Univeristy, Atlanta, Georgia, United States

🇺🇸

University Of Illinois, Chicago, Illinois, United States

🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

and more 17 locations

Single Dose rATG for Renal Allograft Rejection

First Posted Date
2014-04-03
Last Posted Date
2020-09-03
Lead Sponsor
The Methodist Hospital Research Institute
Target Recruit Count
30
Registration Number
NCT02102854
Locations
🇺🇸

Houston Methodist Hospital, Houston, Texas, United States

Everolimus + Very Low Tacrolimus vs Enteric-coated Mycophenolate Sodium + Low Tacrolimus in de Novo Renal Transplant

First Posted Date
2014-03-12
Last Posted Date
2019-02-22
Lead Sponsor
Ronaldo de Matos Esmeraldo, MD
Target Recruit Count
120
Registration Number
NCT02084446
Locations
🇧🇷

Hospital Geral de Fortaleza, Fortaleza, Ceará, Brazil

Different Doses of Anti-thymocyte Globin to Treat Child Severe Aplastic Anemia

Phase 4
Conditions
Interventions
First Posted Date
2013-11-28
Last Posted Date
2013-12-03
Lead Sponsor
Chinese Academy of Medical Sciences
Target Recruit Count
100
Registration Number
NCT01997372
Locations
🇨🇳

Department of Pediatrics, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, Tianjin, Tianjin, China

Preemptive Therapy of GVHD

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2013-11-26
Last Posted Date
2023-11-30
Lead Sponsor
University of Calgary
Target Recruit Count
70
Registration Number
NCT01994824
Locations
🇨🇦

Alberta Health Services-CancerControl / University of Calgary / University of Alberta (Edmonton), Calgary, Alberta, Canada

© Copyright 2024. All Rights Reserved by MedPath