MedPath

Olorinab

Generic Name
Olorinab
Drug Type
Small Molecule
Chemical Formula
C18H23N5O3
CAS Number
1268881-20-4
Unique Ingredient Identifier
581F7DFA9B
Background

Olorinab is under investigation in clinical trial NCT03155945 (Tolerability, Pharmacokinetics, and Efficacy of APD371 in Subjects With Crohn's Disease Experiencing Abdominal Pain).

Effect of Olorinab on Gastrointestinal Transit in Patients With Irritable Bowel Syndrome

Phase 1
Terminated
Conditions
Irritable Bowel Syndrome
Interventions
Drug: Placebo
First Posted Date
2020-12-07
Last Posted Date
2021-05-17
Lead Sponsor
Arena Pharmaceuticals
Target Recruit Count
1
Registration Number
NCT04655599
Locations
🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

Olorinab in Irritable Bowel Syndrome With Predominant Constipation (IBS-C) and Irritable Bowel Syndrome With Predominant Diarrhea (IBS-D)

Phase 2
Terminated
Conditions
Irritable Bowel Syndrome
Interventions
Drug: Placebo
First Posted Date
2019-08-02
Last Posted Date
2025-01-30
Lead Sponsor
Arena Pharmaceuticals
Target Recruit Count
273
Registration Number
NCT04043455
Locations
🇺🇸

WR-ClinSearch, LLC, Chattanooga, Tennessee, United States

🇺🇸

Rapid Medical Research, Inc., Cleveland, Ohio, United States

🇺🇸

New River Valley Research Institute, Christiansburg, Virginia, United States

and more 66 locations

Tolerability, Pharmacokinetics, and Efficacy of APD371 in Participants With Crohn's Disease Experiencing Abdominal Pain

Phase 2
Completed
Conditions
Crohn's Disease
Abdominal Pain
Interventions
First Posted Date
2017-05-16
Last Posted Date
2021-11-02
Lead Sponsor
Arena Pharmaceuticals
Target Recruit Count
14
Registration Number
NCT03155945
Locations
🇺🇸

University of Michigan Medical Center, Ann Arbor, Michigan, United States

🇺🇸

Northwestern University, Chicago, Illinois, United States

🇺🇸

Hassman Research Institute, Berlin, New Jersey, United States

and more 4 locations
© Copyright 2025. All Rights Reserved by MedPath