Prednisolone

Generic Name
Prednisolone
Brand Names
Millipred Dp 6 Day
Drug Type
Small Molecule
Chemical Formula
C21H28O5
CAS Number
50-24-8
Unique Ingredient Identifier
9PHQ9Y1OLM
Background

Prednisolone is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects.

Prednisolone was granted FDA approval on 21 June 1955.

Indication

Prednisolone is indicated to treat endocrine, rheumatic, and hematologic disorders; collagen, dermatologic, ophthalmic, respiratory, and gastrointestinal diseases; allergic and edematous states; and other conditions like tuberculous meningitis.

Associated Conditions
Acute Gouty Arthritis, Acute Leukemia, Allergic Bronchopulmonary Aspergillosis, Allergic Conjunctivitis (AC), Allergic Contact Dermatitis, Allergic Skin Reaction, Allergic corneal marginal ulcers, Alveolitis, Extrinsic Allergic, Ankylosing Spondylitis (AS), Aspiration Pneumonia, Aspiration Pneumonitis, Atopic Dermatitis, Bell's Palsy, Berylliosis, Bullous dermatitis herpetiformis, Burns, Chorioretinitis, Choroiditis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Conjunctivitis, Contact Dermatitis, Corneal injuries, Corneal ulceration, Crohn's Disease (CD), Cyclitis, Dermatomyositis (DM), Dermatosis of the Ear Canal, Drug hypersensitivity reaction, Edema of the cerebrum, Epicondylitis, Erythroblastopenia, Exacerbation of COPD, Exacerbation of asthma, Eye inflammation caused by Cataract Surgery, Eye inflammation caused by Infection, Fissure;Anal, Herpes Zoster Keratitis, Hot Water Burns (Scalds), Hypercalcemia of Malignancy, Idiopathic Pulmonary Fibrosis (IPF), Immune Thrombocytopenia (ITP), Inflamed External Hemorrhoid, Inflamed Hemorrhoids, Internal, Inflammatory Reaction caused by susceptible Bacterial Infections, Iridocyclitis, Iritis, Itching caused by susceptible Bacterial Infections, Keratitis, Loeffler's syndrome, Lymphoma, Metastatic Castration-Resistant Prostate Cancer (mCRPC), Multiple sclerosis exacerbation, Mycosis Fungoides (MF), Ocular Inflammation, Ophthalmia, Sympathetic, Optic Neuritis, Otic Eczema, Pemphigus, Perennial Allergic Rhinitis (PAR), Pericarditis, Pneumocystis Jirovecii Pneumonia, Polymyalgia Rheumatica (PMR), Posterior Uveitis, Posttraumatic Osteoarthritis, Proctitis, Proteinuria, Pruritus, Pruritus Ani, Psoriatic Arthritis, Pulmonary Tuberculosis (TB), Pure Red Cell Aplasia, Rash, Relapsing Polychondritis, Rheumatoid Arthritis, Rheumatoid Arthritis, Juvenile, Rosacea, Seasonal Allergic Rhinitis, Secondary Adrenal Insufficiency, Secondary thrombocytopenia, Serum Sickness, Severe Asthma, Sjogren's Syndrome (SS), Stevens-Johnson Syndrome, Superficial punctate keratitis, Synovitis, Systemic Lupus Erythematosus, Transplanted Organ Rejection, Trichinosis, Tuberculosis (TB), Tuberculous Meningitis, Ulcerative Colitis, Uveitis, Vasculitis, Acquired immune hemolytic anemia, Acute Bursitis, Acute Rheumatic heart disease, unspecified, Acute Tenosynovitis, Anal eczema, Bacterial skin infections, Exfoliative erythroderma, Idiopathic Bronchiolitis obliterans with organizing pneumonia, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Primary adrenocoritical insufficiency, Severe Psoriasis, Severe Seborrhoeic dermatitis, Severe alcoholic liver disease, Steroid-responsive inflammation of the eye, Subacute Bursitis, Susceptible Bacterial Infections, Symptomatic Sarcoidosis, Varicella-zoster virus acute retinal necrosis
Associated Therapies
-

Safety Study of Calcineurin-Inhibitor-Free Immunosuppression After Liver Transplantation

First Posted Date
2009-04-29
Last Posted Date
2011-09-15
Lead Sponsor
Armin Goralczyk
Target Recruit Count
29
Registration Number
NCT00890253
Locations
🇩🇪

University Medical Center Goettingen, Goettingen, Germany

Timed Release Tablet Prednisone in Polymyalgia Rheumatica

First Posted Date
2009-02-04
Last Posted Date
2022-09-13
Lead Sponsor
University Hospitals Bristol and Weston NHS Foundation Trust
Target Recruit Count
12
Registration Number
NCT00836810
Locations
🇬🇧

University Hospitals Bristol NHS Trust, Bristol, Avon, United Kingdom

CASIMAS: Catumaxomab Safety Phase IIIb Study With Intraperitoneal Infusion in Patients With Malignant Ascites Due to Epithelial Cancers

First Posted Date
2009-01-14
Last Posted Date
2012-10-03
Lead Sponsor
Neovii Biotech
Target Recruit Count
230
Registration Number
NCT00822809
Locations
🇩🇪

Study site, Several, Germany

🇪🇸

Study Site, Several, Spain

A Phase 1 Multiple-Dose Escalation and Single Dose (Tablet) Study of PF-04171327 in Healthy Volunteers

First Posted Date
2008-12-22
Last Posted Date
2009-08-12
Lead Sponsor
Pfizer
Target Recruit Count
78
Registration Number
NCT00812825
Locations
🇧🇪

Pfizer Investigational Site, Bruxelles, Belgium

A Trial of Adjunctive Prednisolone and Mycobacterium w Immunotherapy in Tuberculous Pericarditis

First Posted Date
2008-12-18
Last Posted Date
2014-09-03
Lead Sponsor
University of Cape Town
Target Recruit Count
1400
Registration Number
NCT00810849
Locations
🇿🇦

Groote Schuur Hospital, Cape Town, Western Cape, South Africa

Medical Polypectomy and Predictors of Response

First Posted Date
2008-11-11
Last Posted Date
2008-11-11
Lead Sponsor
University of Dundee
Target Recruit Count
60
Registration Number
NCT00788749
Locations
🇬🇧

Ninewells Hospital and Medical School, Dundee, Angus, United Kingdom

Prednisolone Priming Study in Patients With Chronic Hepatitis B

First Posted Date
2008-10-23
Last Posted Date
2012-05-25
Lead Sponsor
Yun-Fan Liaw
Target Recruit Count
160
Registration Number
NCT00778596
Locations
🇨🇳

Chang Gung Memorial Hospital, Linkou, Taoyuan County, Taiwan

🇨🇳

Chang Gung Memorial Hospital - Chiayi, Chiayi County, Taiwan

🇨🇳

Chang Gung Memorial Hospital - Kaohsiung, Kaohsiung City, Taiwan

and more 1 locations

Anti-Cytokine Therapy for Vasculitis

First Posted Date
2008-09-16
Last Posted Date
2008-09-16
Lead Sponsor
University Hospital Birmingham NHS Foundation Trust
Target Recruit Count
37
Registration Number
NCT00753103
Locations
🇬🇧

University Hospitals Birmingham NHS Foundation Trust, Birmingham, West Midlands, United Kingdom

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