Prednisolone

Generic Name: Prednisolone

Brand Names: Millipred Dp 6 Day

Drug Type: Small Molecule

Chemical Formula: C_₂₁H_₂₈O_₅

CAS Number: 50-24-8

Unique Ingredient Identifier: 9PHQ9Y1OLM

Background: Prednisolone is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects.

Prednisolone was granted FDA approval on 21 June 1955.

Indication: Prednisolone is indicated to treat endocrine, rheumatic, and hematologic disorders; collagen, dermatologic, ophthalmic, respiratory, and gastrointestinal diseases; allergic and edematous states; and other conditions like tuberculous meningitis.

Associated Conditions: Acute Gouty Arthritis, Acute Leukemia, Allergic Bronchopulmonary Aspergillosis, Allergic Conjunctivitis (AC), Allergic Contact Dermatitis, Allergic Skin Reaction, Allergic corneal marginal ulcers, Alveolitis, Extrinsic Allergic, Ankylosing Spondylitis (AS), Aspiration Pneumonia, Aspiration Pneumonitis, Atopic Dermatitis, Bell's Palsy, Berylliosis, Bullous dermatitis herpetiformis, Burns, Chorioretinitis, Choroiditis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Conjunctivitis, Contact Dermatitis, Corneal injuries, Corneal ulceration, Crohn's Disease (CD), Cyclitis, Dermatomyositis (DM), Dermatosis of the Ear Canal, Drug hypersensitivity reaction, Edema of the cerebrum, Epicondylitis, Erythroblastopenia, Exacerbation of COPD, Exacerbation of asthma, Eye inflammation caused by Cataract Surgery, Eye inflammation caused by Infection, Fissure;Anal, Herpes Zoster Keratitis, Hot Water Burns (Scalds), Hypercalcemia of Malignancy, Idiopathic Pulmonary Fibrosis (IPF), Immune Thrombocytopenia (ITP), Inflamed External Hemorrhoid, Inflamed Hemorrhoids, Internal, Inflammatory Reaction caused by susceptible Bacterial Infections, Iridocyclitis, Iritis, Itching caused by susceptible Bacterial Infections, Keratitis, Loeffler's syndrome, Lymphoma, Metastatic Castration-Resistant Prostate Cancer (mCRPC), Multiple sclerosis exacerbation, Mycosis Fungoides (MF), Ocular Inflammation, Ophthalmia, Sympathetic, Optic Neuritis, Otic Eczema, Pemphigus, Perennial Allergic Rhinitis (PAR), Pericarditis, Pneumocystis Jirovecii Pneumonia, Polymyalgia Rheumatica (PMR), Posterior Uveitis, Posttraumatic Osteoarthritis, Proctitis, Proteinuria, Pruritus, Pruritus Ani, Psoriatic Arthritis, Pulmonary Tuberculosis (TB), Pure Red Cell Aplasia, Rash, Relapsing Polychondritis, Rheumatoid Arthritis, Rheumatoid Arthritis, Juvenile, Rosacea, Seasonal Allergic Rhinitis, Secondary Adrenal Insufficiency, Secondary thrombocytopenia, Serum Sickness, Severe Asthma, Sjogren's Syndrome (SS), Stevens-Johnson Syndrome, Superficial punctate keratitis, Synovitis, Systemic Lupus Erythematosus, Transplanted Organ Rejection, Trichinosis, Tuberculosis (TB), Tuberculous Meningitis, Ulcerative Colitis, Uveitis, Vasculitis, Acquired immune hemolytic anemia, Acute Bursitis, Acute Rheumatic heart disease, unspecified, Acute Tenosynovitis, Anal eczema, Bacterial skin infections, Exfoliative erythroderma, Idiopathic Bronchiolitis obliterans with organizing pneumonia, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Primary adrenocoritical insufficiency, Severe Psoriasis, Severe Seborrhoeic dermatitis, Severe alcoholic liver disease, Steroid-responsive inflammation of the eye, Subacute Bursitis, Susceptible Bacterial Infections, Symptomatic Sarcoidosis, Varicella-zoster virus acute retinal necrosis

Associated Therapies: -

Clinical Trials

Comparison Between Symbicort® and Prednisolone in COPD

Phase 3

Completed

Conditions: Chronic Obstructive Pulmonary Disease

First Posted Date: 2005-12-01

Last Posted Date: 2011-01-24

Lead Sponsor: AstraZeneca

Target Recruit Count: 120

Registration Number: NCT00259779

Locations: 🇸🇪
Research Site, Örebro, Sweden

Prednisolone in Active Ankylosing Spondylitis (AS)

Phase 2

Conditions: Ankylosing Spondylitis

First Posted Date: 2005-10-26

Last Posted Date: 2006-09-11

Lead Sponsor: Charite University, Berlin, Germany

Target Recruit Count: 75

Registration Number: NCT00244166

Locations: 🇩🇪
Charité Campus Benjamin-Franklin Rheumatolgy, Berlin, Germany
🇩🇪
Rheumazentrum Ruhrgebiet, Herne, Germany
🇩🇪
Immanuel Hospital Rheumatology, Berlin, Germany

Use of Montelukast to Treat Children With Mild to Moderate Acute Asthma

Phase 2

Completed

Conditions: Asthma, Bronchial

Interventions: Drug: Montelukast plus prednisolone
Drug: Prednisolone

First Posted Date: 2005-09-21

Last Posted Date: 2014-05-13

Lead Sponsor: The Hospital for Sick Children

Target Recruit Count: 130

Registration Number: NCT00213252

Locations: 🇨🇦
The Hospital for Sick Children, Toronto, Ontario, Canada

A Bioequivalence Study of Tobramycin and Prednisolone Acetate Compared to PredForte

Phase 3

Completed

Conditions: Eye Infections
Postoperative Complications

Interventions: Drug: Prednisolone and Tobramycin
Drug: Prednisolone

First Posted Date: 2005-09-20

Last Posted Date: 2013-03-15

Lead Sponsor: Bausch & Lomb Incorporated

Target Recruit Count: 132

Registration Number: NCT00198523

Locations: 🇺🇸
Cornea Consultants/Laser Eye Consultants of Boston, Boston, Massachusetts, United States
🇺🇸
Donald E. Beahm, MD, Great Bend, Kansas, United States
🇺🇸
Great Lakes Eye Care, St. Joseph, Michigan, United States

and more 3 locations