DUOSOL WITH 4 MMOL/L POTASSIUM SOLUTION FOR HAEMOFILTRATION

B. BRAUN SINGAPORE PTE LTD

B. BRAUN SINGAPORE PTE LTD

Therapeutic

Prescription Only

SOLUTION, STERILE

**4.2 Posology and method of administration** The use of solutions for haemofiltration in patients with acute renal failure should be under the direction of a physician with experience in using such treatment. In acute renal failure, treatment is carried out for a limited period and is discontinued when renal function is restored. Posology The filtration rate prescribed is dependent on the clinical status and the body weight of the patient. Unless otherwise prescribed, a filtration rate of 20–25 ml/kg body weight per hour is recommended for the removal of metabolic waste products normally excreted in the urine, depending on the metabolic condition of the patient. A maximum filtration rate of 75 litre per day is recommended. The dose-volume is at the discretion of the physician because the volume of substitution solution depends on the intensity of treatment performed and on the amount of fluid to be replaced in order to achieve fluid balance. Method of administration Intravenous use. The ready-to-use solution for haemofiltration has to be prepared by opening the peel seam. The mixing is performed by twisting the bag five times. For further instructions, see section 6.6 – _please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information_. The ready-to-use solution for haemofiltration is infused into the extracorporeal circulation by means of an infusion pump. During haemofiltration the solution for haemofiltration replaces the ultrafiltrate removed from the blood taking into account overall fluid balance. In acute renal failure, treatment is carried out for a limited time period and is discontinued when renal function is fully restored.