MedPath

Glycerin

Generic Name
Glycerin
Brand Names
Clear Eyes Cooling Comfort, Clear Eyes Redness Relief Reformulated Nov 2011, Fleet Mineral Oil, Genteal Tears, Glycerolyte 57, Pedia-lax Liquid, Preparation H Cream, Procalamine 3, Refresh Optive Advanced, Refresh Optive Extended Therapy, Synovisol, Tears Lubricant
Drug Type
Small Molecule
Chemical Formula
C3H8O3
CAS Number
56-81-5
Unique Ingredient Identifier
PDC6A3C0OX
Background

A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.

Indication

It is used as a solvent, emollient, pharmaceutical agent, and sweetening agent.

Associated Conditions
Cold Sore, Constipation, Dry Mouth, Dry Skin, Dry throat, Edema of the cerebrum, Increase in Intracranial Pressure (ICP), Occasional Constipation, Ocular Discomfort, Ocular Hypertension, Ocular Irritation, Skin Infections, Sore Throat, Mouth soreness, Sensation of burning in the eyes
Associated Therapies
Bowel preparation therapy, Topical Antisepsis, Skin protection

An Interdisciplinary Approach to the Treatment of Encopresis in Children With Autism Spectrum Disorders

Not Applicable
Completed
Conditions
Autistic Disorder
Encopresis
Interventions
First Posted Date
2015-03-09
Last Posted Date
2018-07-02
Lead Sponsor
Emory University
Target Recruit Count
22
Registration Number
NCT02383758
Locations
🇺🇸

Marcus Autism Center, Atlanta, Georgia, United States

FARE Peanut SLIT and Early Tolerance Induction

Phase 2
Completed
Conditions
Food Hypersensitivity
Peanut Allergy
Peanut Hypersensitivity
Food Allergy
Interventions
First Posted Date
2014-12-02
Last Posted Date
2022-01-10
Lead Sponsor
University of North Carolina, Chapel Hill
Target Recruit Count
50
Registration Number
NCT02304991
Locations
🇺🇸

University of Texas Southwestern Medical Center, Dallas, Texas, United States

🇺🇸

University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States

Glycerin Suppositories Used Prophylactically in Premature Infants (SUPP): a Pilot Randomized Placebo-controlled Trial

Not Applicable
Conditions
Feeding Intolerance in Premature Infants
Interventions
Other: Sham Suppository
First Posted Date
2014-06-03
Last Posted Date
2016-03-17
Lead Sponsor
McMaster University
Target Recruit Count
30
Registration Number
NCT02153606
Locations
🇨🇦

McMaster University Medical Centre, Hamilton, Ontario, Canada

Glycerin Suppositories for Treatment of Feeding Intolerance in Preterm Infants

Not Applicable
Conditions
Feeding Intolerance
Interventions
Other: Control
Procedure: Rectal stimulation
First Posted Date
2014-05-29
Last Posted Date
2015-04-03
Lead Sponsor
King Saud Medical City
Target Recruit Count
230
Registration Number
NCT02149407
Locations
🇸🇦

King Saud Medical City, Riyadh, Saudi Arabia

🇸🇦

Sulaiman Al Habib Medical Group, Riyadh, Saudi Arabia

Phase 3 Study to Compare the Efficacy and Safety of AR01 to a Placebo Solution for Relief of Pain in Acute Otitis Media

Phase 3
Completed
Conditions
Acute Otitis Media
Interventions
First Posted Date
2014-01-24
Last Posted Date
2015-04-08
Lead Sponsor
Arbor Pharmaceuticals, Inc.
Target Recruit Count
304
Registration Number
NCT02044341
Locations
🇺🇸

PMG Research of Bristol, Bristol, Tennessee, United States

🇺🇸

The Iowa Clinic, Pc, West Des Moines, Iowa, United States

🇺🇸

Clinical Research Center, Las Vegas, Nevada, United States

and more 26 locations

Efficacy of Prophylactic Glycerin Suppositories for Feeding Intolerance in Very Low Birth Weight Preterm Infants: a Randomized Trial

Not Applicable
Terminated
Conditions
Infant, Very Low Birth Weight
Interventions
First Posted Date
2013-02-27
Last Posted Date
2024-03-06
Lead Sponsor
King Faisal Specialist Hospital & Research Center
Target Recruit Count
220
Registration Number
NCT01799629
Locations
🇸🇦

King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia

🇸🇦

Sulaiman Al habib Medical Center, Riyadh, Saudi Arabia

🇸🇦

Security Forces Hospital, Riyadh, Saudi Arabia

Glycerin Suppositories to Reduce Jaundice in Premature Infants

Not Applicable
Completed
Conditions
Idiopathic Hyperbilirubinemia
Neonatal Hyperbilirubinemia
Prematurity
Interventions
Procedure: Phototherapy
First Posted Date
2012-12-11
Last Posted Date
2015-12-09
Lead Sponsor
University of Rochester
Target Recruit Count
79
Registration Number
NCT01746511
Locations
🇺🇸

University of Rochester Medical Center NICU, Rochester, New York, United States

A Trial of Docusate Sodium and Sorbitol Rectal Solution for the in Patients With Constipation

Phase 3
Completed
Conditions
Constipation
Interventions
First Posted Date
2011-11-18
Last Posted Date
2012-09-25
Lead Sponsor
Ferring Pharmaceuticals
Target Recruit Count
300
Registration Number
NCT01474499
Locations
🇨🇳

Nanjing First Hospital, Nanjing, Jiangsu, China

🇨🇳

The Second Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China

🇨🇳

Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China

and more 6 locations

Investigation of KLYX in Patients With Constipation

Phase 2
Completed
Conditions
Constipation
Interventions
Drug: KLYX
First Posted Date
2011-04-14
Last Posted Date
2012-02-06
Lead Sponsor
Ferring Pharmaceuticals
Target Recruit Count
60
Registration Number
NCT01335386
Locations
🇨🇳

Changhai Hospital, The Second Military Medical University, Shanghai, China

🇨🇳

Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China

🇨🇳

Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China

Assessing Maternal Post-partum Pain With Suppositories

First Posted Date
2011-01-07
Last Posted Date
2018-03-07
Lead Sponsor
Loyola University
Target Recruit Count
100
Registration Number
NCT01271855
Locations
🇺🇸

Gottlieb Memorial Hospital, Melrose Park, Illinois, United States

🇺🇸

Loyola Univeristy Medical Center, Maywood, Illinois, United States

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