Benzocaine
- Generic Name
- Benzocaine
- Brand Names
- Anbesol Cold Sore Therapy, Cepacol Sore Throat Plus Cough, Cetacaine, Chloraseptic Sore Throat, Chloraseptic Sore Throat + Cough, Diphen, Docusol Plus, Enemeez Plus, Medicaine Sting and Bite, One Touch Reformulated Apr 2009, Orasep Reformulated Dec 2013, Rectogel, Salinocaine, Topex, Vagisil Original Formula, Zap, Zilactin-B
- Drug Type
- Small Molecule
- Chemical Formula
- C9H11NO2
- CAS Number
- 94-09-7
- Unique Ingredient Identifier
- U3RSY48JW5
- Background
Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. It is commonly used for local anesthesia in many over the counter products. Benzocaine was first used for local anesthesia in dentistry.
- Indication
Benzocaine is indicated for local anesthesia in dentistry, minor trauma, and as preparation for infiltrative anesthesia. Benzocaine products are indicated for topical anesthesia in a wide variety of conditions including skin irritation, oral pain, and hemorrhoids.
- Associated Conditions
- Acute Sore Throat Pain, Dental Pain, Gangrene Stomatitis, Gingivitis, Haemorrhoids, Laryngitis, Pharyngitis, Premature Ejaculation, Secondary Bacterial Infection caused by Tonsillectomy, Secondary Bacterial Infection caused by Tooth Extractions, Skin Irritation, Sore Throat, Stomatitis, Sunburn, Teething pain, Tonsillitis, Tooth Pain, Vomiting, Pruritic dermatosis, Ulceration of the mouth
- Associated Therapies
- Buccopharyngeal anesthesia
Pain Reduction Using Vibration and Topical Anesthesia
- Conditions
- Pain Management
- Interventions
- Device: Powered Toothbrush
- First Posted Date
- 2025-03-25
- Last Posted Date
- 2025-04-02
- Lead Sponsor
- University of Lahore
- Target Recruit Count
- 60
- Registration Number
- NCT06804616
- Locations
- 🇵🇰
University Of Lahore, Lahore, Punjab, Pakistan
Photobiomodulation and Tooth Analgesia
- Conditions
- Dental AnaesthesiaDental PainDental Analgesia
- Interventions
- First Posted Date
- 2024-11-15
- Last Posted Date
- 2025-05-07
- Lead Sponsor
- University of Maryland, Baltimore
- Target Recruit Count
- 200
- Registration Number
- NCT06691269
Pre Injection Use of Cryoanesthesia Versus Topical Anesthetic Gel in Reducing Pain Perception During Palatal Injections
- First Posted Date
- 2023-12-11
- Last Posted Date
- 2023-12-11
- Lead Sponsor
- B.P. Koirala Institute of Health Sciences
- Target Recruit Count
- 60
- Registration Number
- NCT06165432
- Locations
- 🇳🇵
B.P Koirala institute of health sciences, Dharān Bāzār, Koshi, Nepal
Effectiveness of Laser Photobiomodulation Therapy in Reducing Child Pain During Local Anesthesia Injection
- Conditions
- Local Anesthesia Injection Pain
- Interventions
- Device: Photobiomodulation
- First Posted Date
- 2023-05-16
- Last Posted Date
- 2023-05-16
- Lead Sponsor
- Aliaa Hamouda
- Target Recruit Count
- 64
- Registration Number
- NCT05861154
- Locations
- 🇪🇬
Faculty of Dentistry, Alexandria University, Alexandria, Egypt
Compare the Efficacy of Various Pain Alleviating Methods in Reducing Pain in Children During Intraoral Local Anaesthetic Injections
- Conditions
- Anesthesia, Local
- Interventions
- Device: Transcutaneous electric nerve stimuliOther: Ice application
- First Posted Date
- 2022-10-03
- Last Posted Date
- 2022-10-04
- Lead Sponsor
- Minia University
- Target Recruit Count
- 224
- Registration Number
- NCT05564442
- Locations
- 🇪🇬
El Minia university, Minya, Egypt
Emla Cream Versus Benzocaine on Analgesia
- First Posted Date
- 2021-09-29
- Last Posted Date
- 2022-07-29
- Lead Sponsor
- Dow University of Health Sciences
- Target Recruit Count
- 70
- Registration Number
- NCT05060913
- Locations
- 🇵🇰
Dr. Ishrat-ul-Ebad institute of oral health sciences, Karachi, Sindh, Pakistan
Using Anesthetic Gel Patches to Reduce Pain of Palatal Injection
- Conditions
- Anesthesia, Dental
- Interventions
- Drug: Topicale GelPatch (Benzocaine 18%)
- First Posted Date
- 2020-03-23
- Last Posted Date
- 2020-03-23
- Lead Sponsor
- Dina Youssef Attia
- Target Recruit Count
- 50
- Registration Number
- NCT04317508
- Locations
- 🇪🇬
Faculty of Dentistry, Alexandria University, Alexandria, Egypt
Pain Assessment During Mandibular Nerve Block Injection With the Aid of Dental Vibe Tool in Pediatric Dental Patients
- Conditions
- Anesthesia, Local
- Interventions
- Device: DentalVibe
- First Posted Date
- 2018-12-31
- Last Posted Date
- 2020-04-10
- Lead Sponsor
- Nourhan M.Aly
- Target Recruit Count
- 60
- Registration Number
- NCT03790540
- Locations
- 🇪🇬
Faculty of Dentistry, Alexandria University, Alexandria, Egypt
A Study to Determine the Efficacy and Safety of a Benzocaine Lozenge for Treatment of Sore Throat.
- First Posted Date
- 2018-02-14
- Last Posted Date
- 2018-10-18
- Lead Sponsor
- McNeil AB
- Target Recruit Count
- 260
- Registration Number
- NCT03432923
- Locations
- 🇷🇺
Railway Clinical Hospital n.a. N.A. Semashko Lyublino railway station of the Russian Railways, Stavropolskaya str., 23, build.1,, Moscow, Russian Federation
🇷🇺Central Clinical Hospital of Russian Academy of Sciences Litovskiy bulvar, 1A, Moscow, Russian Federation
🇷🇺Federal State Budgetary Institution "Policlinic #5" of Administrative Department of the President of the Russian Federation Plyushchikha str., 14, Moscow, Russian Federation
Phase III Study Evaluating Topical Benzocaine for Treatment of Acute Otitis Media in Children
- Conditions
- PainAcute Otitis Media
- Interventions
- Drug: Placebo
- First Posted Date
- 2017-04-17
- Last Posted Date
- 2017-10-13
- Lead Sponsor
- Lachlan Pharma Holdings
- Target Recruit Count
- 141
- Registration Number
- NCT03116737
- Locations
- 🇺🇸
Cyn3rgy Research, Gresham, Oregon, United States
Drug Development Updates
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