Sugammadex
- Generic Name
- Sugammadex
- Brand Names
- Bridion, Sugammadex Adroiq, Sugammadex Amomed, Sugammadex Fresenius Kabi, Sugammadex Mylan, Sugammadex Piramal
- Drug Type
- Small Molecule
- Chemical Formula
- C72H112O48S8
- CAS Number
- 343306-71-8
- Unique Ingredient Identifier
- 361LPM2T56
- Background
Sugammadex is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery. Rocuronium bromide and vecuronium bromide are neuromuscular blocking medications that cause temporary paralysis and are especially useful for general anesthesia, ventilation, or tracheal intuba...
- Indication
Sugammadex is indicated for the reversal of neuromuscular blockade induced by rocuronium bromide or vecuronium bromide in adults and pediatric patients ≥2 years old who are undergoing surgery.
- Associated Conditions
- Neuromuscular blockade caused by vecuronium bromide
- Associated Therapies
- -
Rocuronium + Sugammadex vs. Succinylcholine + Cisatracurium + Neostigmine/Atropine in Obese Participants (MK-8616-104)
- Conditions
- Interventions
- First Posted Date
- 2015-04-07
- Last Posted Date
- 2015-07-13
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Registration Number
- NCT02410590
Electromyographic Activity of the Respiratory Muscles During Neostigmine or Sugammadex Enhanced Recovery After Neuromuscular Blockade
- Conditions
- Interventions
- First Posted Date
- 2015-03-31
- Last Posted Date
- 2015-11-20
- Lead Sponsor
- Onze Lieve Vrouw Hospital
- Target Recruit Count
- 18
- Registration Number
- NCT02403063
- Locations
- 🇧🇪
OLV Hospital, Aalst, Belgium
Effect of Sugammadex for Muscle Motor Response and Awareness in Intraoperative Wakeup
- First Posted Date
- 2015-03-18
- Last Posted Date
- 2018-03-05
- Lead Sponsor
- Cukurova University
- Target Recruit Count
- 60
- Registration Number
- NCT02390817
- Locations
- 🇹🇷
Ebru Biricik, Adana, Sarıçam, Turkey
🇹🇷Çukurova University, Adana, Çukurova, Turkey
"Low Dose Sugammadex Combined With Neostigmine and Glycopyrrolate Versus Full Dose Sugammadex for Reversal of Rocuronium-induced Neuromuscular Blockade: a Cost Saving Strategy"
- Conditions
- Interventions
- First Posted Date
- 2015-03-02
- Last Posted Date
- 2018-06-27
- Lead Sponsor
- American University of Beirut Medical Center
- Target Recruit Count
- 56
- Registration Number
- NCT02375217
- Locations
- 🇱🇧
AUBMC, Beirut, Lebanon
Effects of Neuromuscular Block Reversal With Sugammadex vs Neostigmine on Postoperative Respiratory Outcomes After Major Abdominal Surgery
- Conditions
- Interventions
- First Posted Date
- 2015-02-11
- Last Posted Date
- 2017-02-23
- Lead Sponsor
- Enrique Alday Muñoz
- Target Recruit Count
- 130
- Registration Number
- NCT02361060
- Locations
- 🇪🇸
Hospital Universitario de La Princesa, Madrid, Spain
🇪🇸Anesthesiology Service. Hospital Universitario La Princesa, Madrid, Spain
Effectiveness of Sugammadex in LMS Surgery
- First Posted Date
- 2015-01-01
- Last Posted Date
- 2015-09-28
- Lead Sponsor
- Korea University Anam Hospital
- Target Recruit Count
- 80
- Registration Number
- NCT02329964
The Clinical Changes Before and After Sugammadex in the Patients Undergoing Hip Surgery on the Aspect of Delirium
- Conditions
- First Posted Date
- 2014-12-02
- Last Posted Date
- 2015-12-16
- Lead Sponsor
- Konkuk University Medical Center
- Target Recruit Count
- 250
- Registration Number
- NCT02305589
- Locations
- 🇰🇷
Konkuk University Medical Center, Seoul, Korea, Republic of
Comparison of the Effects of Neostigmine With Sugammadex on Postoperative Nausea and Vomiting.
- Conditions
- Interventions
- First Posted Date
- 2014-11-10
- Last Posted Date
- 2015-01-13
- Lead Sponsor
- T.C. ORDU ÜNİVERSİTESİ
- Target Recruit Count
- 98
- Registration Number
- NCT02286752
- Locations
- 🇹🇷
Anesthesiology and Reanimation Dept. Ordu University Training and Research Hospital, Altınordu, Ordu, Turkey
Functional Respiratory Imaging After Neostigmine or Sugammadex
- Conditions
- Interventions
- First Posted Date
- 2014-11-06
- Last Posted Date
- 2015-04-21
- Lead Sponsor
- Onze Lieve Vrouw Hospital
- Target Recruit Count
- 13
- Registration Number
- NCT02284412
- Locations
- 🇧🇪
OLV Hospital, Aalst, Belgium
A Randomized Double Blind Controlled Trial Comparing Sugammadex and Neostigmine After Thoracic Anesthesia
- First Posted Date
- 2014-10-03
- Last Posted Date
- 2021-06-16
- Target Recruit Count
- 70
- Registration Number
- NCT02256280
- Locations
- 🇮🇹
Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Mi, Italy
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.