Succinylcholine

Generic Name: Succinylcholine

Brand Names: Anectine, Quelicin

Drug Type: Small Molecule

Chemical Formula: C_₁₄H_₃₀N_₂O_₄

CAS Number: 306-40-1

Unique Ingredient Identifier: J2R869A8YF

Background: Succinylcholine is a depolarizing skeletal muscle relaxant consisting of two molecules of the endogenous neurotransmitter acetylcholine (ACh) linked by their acetyl groups. It has been widely used for over 50 years, most commonly in its chloride salt form, as a means of neuromuscular blockade during intubation and surgical procedures. Its rapid onset and offset, with effects beginning within 60 seconds of intravenous administration and lasting between four to six minutes, make succinylcholine particularly useful in the setting of short medical procedures requiring brief periods of muscle relaxation.

Indication: Succinylcholine is indicated as an adjunct to general anesthesia, to facilitate tracheal intubation, and to provide skeletal muscle relaxation during surgery or mechanical ventilation.

Associated Conditions: -

Associated Therapies: Tracheal Intubation

Clinical Trials

Muscle Relaxant Effect and Safety of Mivacurium Chloride and Succinylcholine for Bronchoscopy

Not Applicable

Not yet recruiting

Conditions: Anesthesia
Bronchoscopy
Muscle Relaxants

Interventions: Drug: mivacurium chloride
Drug: succinylcholine

First Posted Date: 2024-11-29

Last Posted Date: 2024-11-29

Lead Sponsor: Peng Liang

Target Recruit Count: 240

Registration Number: NCT06709066

High-Resolution Solid-State Manometry of the Effect of Succinylcholine on Barrier Pressure

Phase 4

Completed

Conditions: the Effect of Succinylcholine on Barrier Pressure

Interventions: Drug: Succinylcholine

First Posted Date: 2022-09-27

Last Posted Date: 2022-09-27

Lead Sponsor: China-Japan Friendship Hospital

Target Recruit Count: 14

Registration Number: NCT05556408

Intubating Conditions During Rapid Sequence Induction in Elderly With Either Suxamethonium 1.0 mg/kg or Rocuronium 1.0 mg/kg

Phase 4

Completed

Conditions: Intubation Conditions

Interventions: Drug: Suxamethonium
Drug: Rocuronium

First Posted Date: 2021-05-03

Last Posted Date: 2024-03-19

Lead Sponsor: Matias Vested

Target Recruit Count: 102

Registration Number: NCT04868409

Locations: 🇩🇰
Bispebjerg Hospital, Copenhagen, Denmark
🇩🇰
Rigshospitalet, Copenhagen, Denmark
🇩🇰
Department of Anaesthesiology, Pain and Respiratory Support, Rigshospitalet Glostrup, Glostrup, Denmark

and more 1 locations

Effects of Succinylcholine on Nonintubated Thoracoscopic Surgery

Not Applicable

Conditions: Atelectasis
Tumor of Lung Parenchyma
Complication of Ventilation Therapy

Interventions: Drug: Placebo
Drug: Succinylcholine

First Posted Date: 2018-03-19

Last Posted Date: 2018-03-20

Lead Sponsor: National Taiwan University Hospital

Target Recruit Count: 30

Registration Number: NCT03469323

Locations: 🇨🇳
National Taiwan University Hospital, Taipei, Taiwan

Use of Neuromuscular Blocking Agents and Neuromuscular Monitoring in 7 Danish Teaching Hospitals

Completed

Conditions: Neuromuscular Blockade

Interventions: Drug: Rocuronium
Drug: Succinylcholine
Drug: Cisatracurium
Drug: Mivacurium
Device: Objective neuromuscular monitoring (acceleromyography)
Drug: Sugammadex
Drug: Neostigmine

First Posted Date: 2016-09-26

Last Posted Date: 2019-09-12

Lead Sponsor: Jakob Louis Thomsen

Target Recruit Count: 30430

Registration Number: NCT02914119

Locations: 🇩🇰
Herlev Hospital, Herlev, Denmark

General Anesthesia Versus Sedation During Intra-arterial Treatment for Stroke

Phase 3

Completed

Conditions: Stroke

Interventions: Drug: Remifentanil
Drug: Etomidate
Drug: Lidocaine
Drug: Succinylcholine
Drug: Propofol

First Posted Date: 2016-07-04

Last Posted Date: 2023-05-23

Lead Sponsor: Rennes University Hospital

Target Recruit Count: 351

Registration Number: NCT02822144

Locations: 🇫🇷
Fédération d'anesthésie-réanimation - Hôpital Pontchaillou, CHU de Rennes, Rennes, France
🇫🇷
Service d'anesthésie-réanimation - Fondation A. de Rothschild, Paris, France
🇫🇷
Département d'anesthésie-réanimation - Hôpital de la Cavale Blanche, CHU de Brest, Brest, France

and more 1 locations