DeepMed Research

Etomidate

Generic Name: Etomidate

Brand Names: Amidate

Drug Type: Small Molecule

Chemical Formula: C_₁₄H_₁₆N_₂O_₂

CAS Number: 33125-97-2

Unique Ingredient Identifier: Z22628B598

Background: Imidazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular system. It has been proposed as an induction anesthetic.

Indication: Used in the induction of general anesthesia.

Associated Therapies: General Anesthesia

Clinical Trials

A Clinical Trial to Evaluate the Efficacy and Safety of Methoxyethyl Etomidate Hydrochloride for Sedation/Anesthesia During Gastroscopy/Colonoscopy

Phase 3

Not yet recruiting

Conditions: Gastroscopy
Colonoscopy

Interventions: Drug: ET-26HCl 0.8mg/kg group
Drug: Etomidate Injectable Product 0.3mg/kg group

First Posted Date: 2025-03-05

Last Posted Date: 2025-03-05

Lead Sponsor: Ahon Pharmaceutical Co., Ltd.

Target Recruit Count: 270

Registration Number: NCT06858852

Locations: 🇨🇳
Peking University First Hospital, Beijing, Beijing, China
🇨🇳
West China Hospital of Sichuan University, Chengdu, Sichuan, China
🇨🇳
Shenzhen People's Hospital, Shenzhen, Guangdong, China

and more 3 locations

A Trial to Evaluate the Efficacy and Safety of Methoxyethyl Etomidate Hydrochloride in Gastroscopy/Colonoscopy

Phase 2

Not yet recruiting

Conditions: Gastroscopy
Colonoscopy

Interventions: Drug: Etomidate Injectable Product 0.3mg/kg group
Drug: ET-26HCl 0.6mg/kg group
Drug: ET-26HCl 0.8mg/kg group

First Posted Date: 2024-11-11

Last Posted Date: 2024-11-11

Lead Sponsor: Ahon Pharmaceutical Co., Ltd.

Target Recruit Count: 78

Registration Number: NCT06682546

Locations: 🇨🇳
Sichuan Academy of Medical Sciences · Sichuan Provincial People's Hospital, Chengdu, Sichuan, China

Comparison of Remimazolam and Etomidate As Induction Agents for Electroconvulsive Treatment

Phase 4

Completed

Conditions: Schizophenia Disorder
Major Depression Disorders
Schizoaffective Disorder
Bipolar

Interventions: Drug: Remimazolam
Drug: Etomidate

First Posted Date: 2024-10-29

Last Posted Date: 2024-10-31

Lead Sponsor: Yeongseok Yun

Target Recruit Count: 30

Registration Number: NCT06664138

Locations: 🇰🇷
Dankook University Hospital, Cheon-an, Korea, Republic of

A Trial to Evaluate the Efficacy and Safety of Methoxyetomidate Hydrochloride for Injection (ET-26) for the Induction of General Anesthesia in Elective Surgery Subjects

Phase 3

Recruiting

Conditions: Anesthesia Induction

Interventions: Drug: Etomidate Injectable Emulsion
Drug: ET-26

First Posted Date: 2024-01-12

Last Posted Date: 2024-01-12

Lead Sponsor: Ahon Pharmaceutical Co., Ltd.

Target Recruit Count: 270

Registration Number: NCT06203431

Locations: 🇨🇳
West China Hospital of Sichuan University, Chengdu, Sichuan, China

Effect of Ketamine and Etomidate During RSI on Long Term Outcomes

Recruiting

Conditions: Acute Respiratory Failure
Post-Traumatic Stress Disorder

Interventions: Drug: Ketamine
Drug: Etomidate

First Posted Date: 2023-12-22

Last Posted Date: 2025-01-08

Lead Sponsor: Vanderbilt University Medical Center

Target Recruit Count: 1756

Registration Number: NCT06179485

Locations: 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States

Etomidate Versus Propofol in CABG Surgery

Phase 4

Recruiting

Conditions: Coronary Artery Disease

Interventions: Drug: Propofol
Drug: Etomidate

First Posted Date: 2023-10-05

Last Posted Date: 2023-12-28

Lead Sponsor: Hartford Hospital

Target Recruit Count: 300

Registration Number: NCT06068764

Locations: 🇺🇸
Hartford Hospital, Hartford, Connecticut, United States

The Safety of Etomidate - Propofol Mixture vs Propofol in Total Intravenous Anesthesia During Abdominal Surgery

Not Applicable

Recruiting

Conditions: Etomidate
Hypotension

Interventions: Drug: Etomidate - propofol mixture
Drug: Propofol

First Posted Date: 2023-04-12

Last Posted Date: 2024-02-23

Lead Sponsor: Ailin Luo

Target Recruit Count: 468

Registration Number: NCT05810363

Locations: 🇨🇳
Tongji hospital, Wuhan, China

Effect of Remimazolam on the Recovery Quality After Day Surgery

Not Applicable

Completed

Conditions: Ambulatory Surgery
Elderly Patients

Interventions: Drug: Remimazolam besylate
Drug: etomidate

First Posted Date: 2023-03-01

Last Posted Date: 2024-03-13

Lead Sponsor: Xijing Hospital

Target Recruit Count: 118

Registration Number: NCT05748665

Locations: 🇨🇳
Yan 'an University Affiliated Hospital, Yanan, Shannxi, China
🇨🇳
The Fourth military medical university, Xijing Hospital, Xi'an, Shannxi, China
🇨🇳
Xi 'an International Medical Center Hospital, Xi'an, Shannxi, China

Etomidate Induction in Hysteroscopic Surgery

Not Applicable

Conditions: Etomidate Induced Dose
Hysteroscopic Surgery

Interventions: Drug: etomidate
Drug: propofol

First Posted Date: 2022-08-30

Last Posted Date: 2022-08-30

Lead Sponsor: Peking University Third Hospital

Target Recruit Count: 200

Registration Number: NCT05520645

Efficacy and Safety of Etomidate Sedation in Gastric Endoscopic Submucosal Dissection

Not Applicable

Completed

Conditions: Sedation Complication
Endoscopic Submucosal Dissection
Esophagogastroduodenoscopy

Interventions: Drug: Propofol Injection
Drug: Etomidate Injection

First Posted Date: 2022-06-07

Last Posted Date: 2024-11-11

Lead Sponsor: Korea University Anam Hospital

Target Recruit Count: 138

Registration Number: NCT05407870

Locations: 🇰🇷
Korea University Anam Hospital, Seoul, Seoung-buk Gu, Korea, Republic of

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