Mivacurium
- Generic Name
- Mivacurium
- Drug Type
- Small Molecule
- Chemical Formula
- C58H80N2O14
- CAS Number
- 133814-19-4
- Unique Ingredient Identifier
- 77D66S9Q93
- Background
Mivacurium is a bisbenzylisoquinolinium based neuromuscular blocker or muscle relaxant. It binds competitively to cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine, resulting in a block of neuromuscular transmission.
- Indication
For inpatients and outpatients, as an adjunct to general anesthesia, to facilitate tracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
- Associated Therapies
- Curarization therapy, General Anesthesia, Neuromuscular blocking therapy, Facilitation of small bowel intubation therapy, Smooth muscle relaxation prior to radiological procedures therapy
Muscle Relaxant Effect and Safety of Mivacurium Chloride and Succinylcholine for Bronchoscopy
- Conditions
- AnesthesiaBronchoscopyMuscle Relaxants
- Interventions
- First Posted Date
- 2024-11-29
- Last Posted Date
- 2024-11-29
- Lead Sponsor
- Peng Liang
- Target Recruit Count
- 240
- Registration Number
- NCT06709066
Mivacurium 0.2 mg/kg in Young (18 - 40 Years) and Elderly (= 80 Years) Patients
- Conditions
- Onset Time of Mivacurium, Duration of Action of Mivacurium
- Interventions
- First Posted Date
- 2022-09-28
- Last Posted Date
- 2023-11-07
- Lead Sponsor
- Matias Vested
- Target Recruit Count
- 70
- Registration Number
- NCT05558137
- Locations
- 🇩🇰
Rigshospitalet, Copenhagen, Denmark
Use of Neuromuscular Blocking Agents and Neuromuscular Monitoring in 7 Danish Teaching Hospitals
- Conditions
- Neuromuscular Blockade
- Interventions
- Device: Objective neuromuscular monitoring (acceleromyography)
- First Posted Date
- 2016-09-26
- Last Posted Date
- 2019-09-12
- Lead Sponsor
- Jakob Louis Thomsen
- Target Recruit Count
- 30430
- Registration Number
- NCT02914119
- Locations
- 🇩🇰
Herlev Hospital, Herlev, Denmark
Mivacurium Chloramine Muscle Relaxation Effect in Patients With Liver Cirrhosis
- First Posted Date
- 2015-06-16
- Last Posted Date
- 2015-08-21
- Lead Sponsor
- Tang-Du Hospital
- Target Recruit Count
- 80
- Registration Number
- NCT02473601
- Locations
- 🇨🇳
Tangdu hospital, Xi'an, Shanxi, China
A Prospective, Multi-center, Randomized Controlled Study of Muscle Relaxation Effect and Safety of Mivacurium Chloride in Pediatric Surgery Patients
- Conditions
- Efficacy and Safety of Mivacurium Chloride for Pediatric Patients
- Interventions
- First Posted Date
- 2014-04-21
- Last Posted Date
- 2014-07-15
- Lead Sponsor
- Jiangsu Nhwa Pharmaceutical Co., Ltd.
- Target Recruit Count
- 1152
- Registration Number
- NCT02117401
Low Dose Mivacurium vs. Low Dose Succinylcholine for Rigid Bronchoscopy
- Conditions
- Performance With Respiratory Exercise DevicePostoperative MyalgiaIntubating Conditions
- Interventions
- First Posted Date
- 2013-10-21
- Last Posted Date
- 2014-07-30
- Lead Sponsor
- Dr. Horst Schmidt Klinik GmbH
- Target Recruit Count
- 100
- Registration Number
- NCT01966484
- Locations
- 🇩🇪
Dr. Horst Schmidt Klinik GmbH, Wiesbaden, Germany
Sex-related Differences in the Response to the Muscle Relaxant Drug Mivacurium
- First Posted Date
- 2013-07-24
- Last Posted Date
- 2014-04-11
- Lead Sponsor
- University of California, San Francisco
- Target Recruit Count
- 20
- Registration Number
- NCT01906528
- Locations
- 🇺🇸
University of California, UCSF, San Francisco, California, United States
Drug Development Updates
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