MedPath

Prasinezumab

Generic Name
Prasinezumab
Drug Type
Biotech
CAS Number
1960462-19-4
Unique Ingredient Identifier
P3Z0Z3P1ZI
Background

Prasinezumab is under investigation in clinical trial NCT03100149 (A Study to Evaluate the Efficacy of Prasinezumab (RO7046015/PRX002) in Participants With Early Parkinson's Disease).

A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early Parkinson's Disease

Phase 2
Active, not recruiting
Conditions
Parkinsons Disease
Interventions
Drug: Placebo
First Posted Date
2021-03-02
Last Posted Date
2025-04-17
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
586
Registration Number
NCT04777331
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Dent Neurological Institute, Amherst, New York, United States

๐Ÿ‡ฎ๐Ÿ‡น

A.O.U. Policlinico "G.Rodolico - San Marco", Catania, Sicilia, Italy

๐Ÿ‡ฎ๐Ÿ‡น

A.O. Universitaria Pisana, Pisa, Toscana, Italy

and more 107 locations

A Study to Evaluate the Efficacy of Prasinezumab (RO7046015/PRX002) in Participants With Early Parkinson's Disease

Phase 2
Active, not recruiting
Conditions
Parkinson's Disease
Interventions
Drug: Placebo
First Posted Date
2017-04-04
Last Posted Date
2025-04-11
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
316
Registration Number
NCT03100149
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Barrow Neurology Clinics, Phoenix, Arizona, United States

๐Ÿ‡บ๐Ÿ‡ธ

Aventura Neurologic Associates, Aventura, Florida, United States

๐Ÿ‡บ๐Ÿ‡ธ

University of Vermont Medical Center, Burlington, Vermont, United States

and more 49 locations

Multiple Ascending Dose Study of PRX002 in Patients With Parkinson's Disease

Phase 1
Completed
Conditions
Parkinson's Disease
Interventions
Other: Placebo
First Posted Date
2014-06-06
Last Posted Date
2016-10-21
Lead Sponsor
Prothena Biosciences Limited
Target Recruit Count
64
Registration Number
NCT02157714
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Institute for Neurodegenerative Disorders, New Haven, Connecticut, United States

๐Ÿ‡บ๐Ÿ‡ธ

Collaborative Neuroscience Network, LLC, Long Beach, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

Parkinson's Disease and Movement Disorders Center of Boca Raton, Boca Raton, Florida, United States

and more 5 locations

Single Ascending Dose Study of PRX002 in Healthy Subjects

Phase 1
Completed
Conditions
Parkinson's Disease
Interventions
Other: Placebo
First Posted Date
2014-03-24
Last Posted Date
2015-02-10
Lead Sponsor
Prothena Biosciences Limited
Target Recruit Count
40
Registration Number
NCT02095171
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