Danazol
- Generic Name
- Danazol
- Brand Names
- Cyclomen
- Drug Type
- Small Molecule
- Chemical Formula
- C22H27NO2
- CAS Number
- 17230-88-5
- Unique Ingredient Identifier
- N29QWW3BUO
- Background
A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins. It possesses some androgenic properties. Danazol has been used in the treatment of endometriosis and some benign breast disorders.
- Indication
For the treatment of endometriosis and fibrocystic breast disease (in patients unresponsive to simple measures). Also used for the prophylactic treatment of all types of hereditary angioedema in males and females.
- Associated Conditions
- Endometriosis, Fibrocystic Disease of Breast, Hereditary Angioedema (HAE), Refractory immune thrombocytopenia
- Associated Therapies
- -
The Combination of Teriflunomide and Danazol for Steroid-resistant/Relapse Immune Thrombocytopenia
- First Posted Date
- 2023-12-20
- Last Posted Date
- 2023-12-20
- Lead Sponsor
- Peking University People's Hospital
- Target Recruit Count
- 124
- Registration Number
- NCT06176911
- Locations
- 🇨🇳
Peking University Insititute of Hematology, Peking University People's Hospital, Beijing, Beijing, China
Low-dose Baricitinib Plus Danazol for Steroid-resistant/Relapse Immune Thrombocytopenia
- Conditions
- Interventions
- First Posted Date
- 2023-05-10
- Last Posted Date
- 2023-06-13
- Lead Sponsor
- Peking University People's Hospital
- Target Recruit Count
- 216
- Registration Number
- NCT05852847
- Locations
- 🇨🇳
The Sixth Medical Center of PLA General Hospital, Beijing, China
🇨🇳Peking University Insititute of Hematology, Peking University People's Hospital, Beijing, Beijing, China
🇨🇳Beijing Friendship Hospital, Beijing, China
Comparisons of the Therapeutic Effects of Dienogest and Danazol on Endometriosis
- First Posted Date
- 2023-01-26
- Last Posted Date
- 2023-03-29
- Lead Sponsor
- Far Eastern Memorial Hospital
- Target Recruit Count
- 120
- Registration Number
- NCT05697471
- Locations
- 🇨🇳
Department of Obstetrics and Gynecology, Far Eastern Memorial Hospital, Banqiao, New Taipei, Taiwan
The Combination of Terbutaline and Danazol as the Treatment of Corticosteroid-resistant/Relapse Immune Thrombocytopenia
- First Posted Date
- 2022-08-09
- Last Posted Date
- 2022-08-09
- Lead Sponsor
- Peking University People's Hospital
- Target Recruit Count
- 228
- Registration Number
- NCT05494307
The Combination of Tacrolimus and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia
- First Posted Date
- 2022-07-22
- Last Posted Date
- 2022-07-22
- Lead Sponsor
- Peking University People's Hospital
- Target Recruit Count
- 120
- Registration Number
- NCT05471050
- Locations
- 🇨🇳
Peking University Insititute of Hematology, Peking University People's Hospital, Beijing, Beijing, China
The Combination of Sitagliptin and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia
- First Posted Date
- 2022-04-29
- Last Posted Date
- 2022-04-29
- Lead Sponsor
- Peking University People's Hospital
- Target Recruit Count
- 120
- Registration Number
- NCT05353673
- Locations
- 🇨🇳
Peking University Insititute of Hematology, Peking University People's Hospital, Beijing, Beijing, China
The Combination of Iguratimod and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia
- First Posted Date
- 2022-03-15
- Last Posted Date
- 2022-05-02
- Lead Sponsor
- Peking University People's Hospital
- Target Recruit Count
- 120
- Registration Number
- NCT05281068
- Locations
- 🇨🇳
Zhuo-Yu An, Beijing, China
🇨🇳Peking University Insititute of Hematology, Peking University People's Hospital, Beijing, China
Repurposed Drugs to Improve Haematological Responses in Myelodysplastic Syndromes
- Conditions
- Interventions
- First Posted Date
- 2021-08-10
- Last Posted Date
- 2023-10-03
- Lead Sponsor
- Prof. Janet Dunn
- Target Recruit Count
- 120
- Registration Number
- NCT04997811
- Locations
- 🇬🇧
Royal Hampshire County Hospital, Hampshire Hospitals NHS Foundation Trust, Winchester, Hampshire, United Kingdom
🇬🇧Nottingham City Hospital, Nottingham University Hospitals NHS Trust, Hucknall Road, Nottingham, Nottinghamshire, United Kingdom
🇬🇧Royal Cornwall Hospital NHS Trust, Truro, Cornwall, United Kingdom
Study of Exposure to Substances Prohibited by the World Anti-Doping Agency in Healthy Volunteers.
- Conditions
- Interventions
- First Posted Date
- 2021-02-17
- Last Posted Date
- 2021-04-26
- Lead Sponsor
- Parc de Salut Mar
- Target Recruit Count
- 9
- Registration Number
- NCT04757532
- Locations
- 🇪🇸
IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain
The TELO-SCOPE Study: Attenuating Telomere Attrition With Danazol. Is There Scope to Dramatically Improve Health Outcomes for Adults and Children With Pulmonary Fibrosis
- Conditions
- Interventions
- First Posted Date
- 2020-11-20
- Last Posted Date
- 2024-01-23
- Lead Sponsor
- The University of Queensland
- Target Recruit Count
- 50
- Registration Number
- NCT04638517
- Locations
- 🇦🇺
Sydney Children's Hospital, Sydney, New South Wales, Australia
🇦🇺Royal Adelaide Hospital, Adelaide, South Australia, Australia
🇦🇺Royal Prince Alfred Hospital, Sydney, New South Wales, Australia
Drug Development Updates
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