Cisplatin

Generic Name
Cisplatin
Brand Names
Platinol
Drug Type
Small Molecule
Chemical Formula
Cl2H6N2Pt
CAS Number
15663-27-1
Unique Ingredient Identifier
Q20Q21Q62J
Background

Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.

Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Associated Conditions
Advanced Ovarian Cancer, Ovarian Cancer Metastatic, Advanced Bladder cancer, Advanced Testicular cancer, Metastatic Testicular cancer
Associated Therapies
-

Perioperative Gemcitabine, Cisplatin, and Pembrolizumab in Potentially Resectable Biliary Tract Cancers

First Posted Date
2023-08-21
Last Posted Date
2024-07-25
Lead Sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Target Recruit Count
27
Registration Number
NCT06001658
Locations
🇺🇸

SKCCC Johns Hopkins, Baltimore, Maryland, United States

Cadonilimab With Chemotherapy in Treating Advanced Biliary Cancer

First Posted Date
2023-08-07
Last Posted Date
2023-08-07
Lead Sponsor
West China Hospital
Target Recruit Count
65
Registration Number
NCT05978609
Locations
🇨🇳

West China Hospital, Sichuan University, Chengdu, Sichuan, China

Treating Muscle-invasive Bladder Cancer With A Non-surgical Method Consisting of Anti-PD-1 Therapy and Chemoradiation

First Posted Date
2023-08-03
Last Posted Date
2023-12-19
Lead Sponsor
Sun Yat-sen University
Target Recruit Count
64
Registration Number
NCT05975307
Locations
🇨🇳

Cancer Center, Sun Yat-sen University, Guangzhou, Guangdong, China

A Single-Arm Study of Pembrolizumab With Gemcitabine and Cisplatin as Perioperative Therapy for Potentially Resectable Intrahepatic Cholangiocarcinoma

First Posted Date
2023-08-01
Last Posted Date
2024-03-21
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
24
Registration Number
NCT05967182
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Phase 2 Futibatinib in Combination With PD-1 Antibody Based Standard of Care in Solid Tumors

First Posted Date
2023-07-14
Last Posted Date
2024-12-02
Lead Sponsor
Taiho Oncology, Inc.
Target Recruit Count
66
Registration Number
NCT05945823
Locations
🇺🇸

University of California Los Angeles UCLA - Cancer Care - Santa Monica, Santa Monica, California, United States

🇺🇸

Rocky Mountain Cancer Centers Midtown, Denver, Colorado, United States

🇺🇸

Mount Sinai Comprehensive Cancer Center, Miami Beach, Florida, United States

and more 19 locations

Pembrolizumab in Locally Advanced Sinonasal Carcinoma

First Posted Date
2023-06-29
Last Posted Date
2024-12-18
Lead Sponsor
Istituti Clinici Scientifici Maugeri SpA
Target Recruit Count
28
Registration Number
NCT05925491
Locations
🇮🇹

Istituti Clinici Scientifici Maugeri, Pavia, Lombardia, Italy

A Study of Chemoradiation in Combination with Tislelizumab As First Line Treatment in Participants with Advanced Esophageal Squamous Cell Carcinoma

First Posted Date
2023-06-26
Last Posted Date
2024-11-14
Lead Sponsor
Renmin Hospital of Wuhan University
Target Recruit Count
155
Registration Number
NCT05919030
Locations
🇨🇳

Renmin hosptial of Wuhan University, Wuhan, Hubei, China

A Study of PM8002 Injection in Combination With Standard Chemotherapy as First Line Therapy in MPM

First Posted Date
2023-06-26
Last Posted Date
2023-06-27
Lead Sponsor
Biotheus Inc.
Target Recruit Count
55
Registration Number
NCT05918107
Locations
🇨🇳

Jilin Provincial Tumor Hospital, Changchun, China

Disitamab Vedotin With Pembrolizumab vs Chemotherapy in Previously Untreated Urothelial Cancer Expressing HER2

First Posted Date
2023-06-22
Last Posted Date
2024-11-13
Lead Sponsor
Seagen Inc.
Target Recruit Count
700
Registration Number
NCT05911295
Locations
🇺🇸

Inova Schar Cancer Institute, Fairfax, Virginia, United States

🇧🇷

Hospital de Cancer de Barretos - Fundacao Pio XII, Barretos, Other, Brazil

🇧🇷

Centro de Oncologia da Bahia, Salvador, Other, Brazil

and more 113 locations
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