Cisplatin

Generic Name
Cisplatin
Brand Names
Platinol
Drug Type
Small Molecule
Chemical Formula
Cl2H6N2Pt
CAS Number
15663-27-1
Unique Ingredient Identifier
Q20Q21Q62J
Background

Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.

Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Associated Conditions
Advanced Ovarian Cancer, Ovarian Cancer Metastatic, Advanced Bladder cancer, Advanced Testicular cancer, Metastatic Testicular cancer
Associated Therapies
-

Concurrent and Adjuvant Nimotuzumab Combined With Induction Chemotherapy Plus Chemoradiation in Nasopharyngeal Carcinoma

First Posted Date
2023-02-08
Last Posted Date
2023-02-08
Lead Sponsor
Fourth Affiliated Hospital of Guangxi Medical University
Target Recruit Count
288
Registration Number
NCT05717790
Locations
🇨🇳

Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi, China

🇨🇳

Guilin Medical University, China, Guilin, Guangxi, China

🇨🇳

Nanxishan Hospital of Guangxi Zhuang Autonomous Region, Guilin, Guangxi, China

and more 6 locations

A Study of LSTA1 When Added to Standard of Care Versus Standard of Care Alone in Patients With Advanced Solid Tumors

First Posted Date
2023-02-03
Last Posted Date
2024-12-13
Lead Sponsor
Lisata Therapeutics, Inc.
Target Recruit Count
80
Registration Number
NCT05712356
Locations
🇪🇸

Hospital Universitario de Vinalopó, Elche, Alicante, Spain

🇪🇸

Hospital Universitario de Jerez, Jerez De La Frontera, Cadiz, Spain

🇪🇸

Start Madrid - Hospital Universitario HM Sanchinarro, Madrid, Spain

and more 23 locations

Applicability of 3D-HDRA in Patients With Primary Liver Cancer: A Randomized Controlled Trial

First Posted Date
2023-01-27
Last Posted Date
2023-03-02
Lead Sponsor
Zhujiang Hospital
Target Recruit Count
144
Registration Number
NCT05701436
Locations
🇨🇳

Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China

A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

First Posted Date
2023-01-20
Last Posted Date
2024-12-13
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
1122
Registration Number
NCT05691478
Locations
🇺🇸

Newark Beth Israel Medical Center, Newark, New Jersey, United States

🇺🇸

State University of New York Upstate Medical University, Syracuse, New York, United States

🇺🇸

Alfred I duPont Hospital for Children, Wilmington, Delaware, United States

and more 89 locations

Pemetrexed-free vs. Pemetrexed-based Immunochemotherapy in Metastatic TTF-1 Negative Lung Adenocarcinoma

First Posted Date
2023-01-19
Last Posted Date
2024-10-26
Lead Sponsor
Nikolaj Frost MD
Target Recruit Count
136
Registration Number
NCT05689671
Locations
🇩🇪

LungenClinic Großhansdorf GmbH, Großhansdorf, Germany

🇩🇪

Universitätsmedizin Göttingen, Göttingen, Germany

🇩🇪

Asklepios Klinkum Hamburg, Hamburg, Germany

and more 28 locations

Phase III, Open-label, First-line Study of Dato-DXd in Combination With Durvalumab and Carboplatin for Advanced NSCLC Without Actionable Genomic Alterations

First Posted Date
2023-01-18
Last Posted Date
2024-12-02
Lead Sponsor
AstraZeneca
Target Recruit Count
1350
Registration Number
NCT05687266
Locations
🇻🇳

Research Site, Ho Chi Minh, Vietnam

Radiotherapy Alone Versus Concurrent Chemo-radiotherapy for Nasopharyngeal Carcincoma Patients With Undectable EBV DNA After One Cylce Neoadjuvant Chemotherpy

Phase 3
Recruiting
Conditions
Interventions
First Posted Date
2023-01-06
Last Posted Date
2023-01-10
Lead Sponsor
Fudan University
Target Recruit Count
366
Registration Number
NCT05674305
Locations
🇨🇳

Fudan Universtiy Shanghai Cancer Centre, Shanghai, Shanghai, China

Durvalumab Combined With GemCis Neoadjuvant Therapy of Resectable Intrahepatic Cholangiocarcinoma With High Recurrence Risk

First Posted Date
2023-01-05
Last Posted Date
2023-01-05
Lead Sponsor
Tianjin Medical University Cancer Institute and Hospital
Target Recruit Count
70
Registration Number
NCT05672537
Locations
🇨🇳

Tianjin Medical University Cancer Institute and Hospital, Tianjin, Tianjin, China

Treatment of Advance Gastric Cancer With Disulfiram

First Posted Date
2022-12-28
Last Posted Date
2022-12-28
Lead Sponsor
First People's Hospital of Hangzhou
Target Recruit Count
40
Registration Number
NCT05667415
Locations
🇨🇳

Hangzhou first people's Hospital, Hangzhou, Zhejiang, China

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