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Lisata Therapeutics

🇺🇸United States
Ownership
Public
Employees
25
Market Cap
-
Website
http://www.lisata.com
Introduction

Lisata Therapeutics, Inc. is engaged in the discovery, development, and commercialization of innovative therapies for the treatment of advanced solid tumors and other major diseases. Its product, LSTA1, is designed to activate a novel uptake pathway that allows co-administered or tethered anti-cancer drugs to target and penetrate tumors. It also actuates this active transport system in a tumor-specific manner, resulting in systemically co-administered anti-cancer drugs more efficiently penetrating and accumulating in the tumor, while normal tissues are unlikely to be affected. The company was founded in 1980 and is headquartered in Basking Ridge, NJ.

Clinical Trials

17

Active:1
Completed:10

Trial Phases

3 Phases

Phase 1:6
Phase 2:8
Phase 3:2

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (16 trials with phase data)• Click on a phase to view related trials

Phase 2
8 (50.0%)
Phase 1
6 (37.5%)
Phase 3
2 (12.5%)

Certepetide Phase 1b/2a Continuous Infusion Trial in mPDAC

Phase 1
Withdrawn
Conditions
Pancreas Cancer
Pancreatic Carcinoma
Pancreas Adenocarcinoma
Pancreatic Ductal Adenocarcinoma
Unresectable Pancreatic Cancer
Metastatic Pancreatic Cancer
PDAC
PDAC - Pancreatic Ductal Adenocarcinoma
Interventions
First Posted Date
2024-09-19
Last Posted Date
2025-06-06
Lead Sponsor
Lisata Therapeutics, Inc.
Target Recruit Count
30
Registration Number
NCT06592664

A Study of LSTA1 When Added to Standard of Care Versus Standard of Care Alone in Patients With Advanced Solid Tumors

Phase 2
Active, not recruiting
Conditions
Cholangiocarcinoma
Intrahepatic Cholangiocarcinoma
Gall Bladder Cancer
Gallbladder Cancer
Extrahepatic Cholangiocarcinoma
Bile Duct Cancer
Gall Bladder Carcinoma
Gallbladder Carcinoma
Interventions
First Posted Date
2023-02-03
Last Posted Date
2025-06-06
Lead Sponsor
Lisata Therapeutics, Inc.
Target Recruit Count
67
Registration Number
NCT05712356
Locations
🇺🇸

Banner MD Anderson Cancer Center, Gilbert, Arizona, United States

🇺🇸

Mayo Clinic Arizona, Phoenix, Arizona, United States

🇺🇸

University of Arizona Cancer Center, Tucson, Arizona, United States

and more 16 locations

CLBS201 in Patients with Chronic Kidney Disease (CKD) and Type 2 Diabetes Mellitus (T2DM)

Phase 1
Completed
Conditions
Chronic Kidney Diseases
Interventions
First Posted Date
2021-08-04
Last Posted Date
2024-10-09
Lead Sponsor
Lisata Therapeutics, Inc.
Target Recruit Count
6
Registration Number
NCT04990427
Locations
🇺🇸

Clinical Advancement Center, PLLC, San Antonio, Texas, United States

A Placebo-Controlled Trial of CLBS16 in Subjects With Coronary Microvascular Dysfunction

Phase 2
Terminated
Conditions
Coronary Microvascular Disease
Microvascular Coronary Artery Disease
Coronary Microvascular Dysfunction
First Posted Date
2020-11-04
Last Posted Date
2023-10-17
Lead Sponsor
Lisata Therapeutics, Inc.
Target Recruit Count
34
Registration Number
NCT04614467
Locations
🇺🇸

Cedars-Sinai Medical Center, Los Angeles, California, United States

🇺🇸

University of Florida - College of Medicine/ div of Cardiovascular Medicine, Gainesville, Florida, United States

🇺🇸

Memorial Regional Hospital, Hollywood, Florida, United States

and more 4 locations

CLBS119 for Repair of COVID-19 Induced Pulmonary Damage

Phase 1
Withdrawn
Conditions
Covid-19
Interventions
First Posted Date
2020-08-21
Last Posted Date
2024-10-09
Lead Sponsor
Lisata Therapeutics, Inc.
Registration Number
NCT04522817
Locations
🇺🇸

NYU Langone Health, New York, New York, United States

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News

Lisata's Certepetide Shows Promising Results in Phase 2b Pancreatic Cancer Trial

Lisata Therapeutics' certepetide demonstrated significant improvements in progression-free survival and response rates when combined with standard chemotherapy in metastatic pancreatic cancer patients.

Critical Limb Ischemia Market Projected to Reach $2.5 Billion by 2035, Driven by Novel Therapies and Advanced Diagnostics

The critical limb ischemia (CLI) market is expected to grow from $1.4 billion in 2024 to $2.5 billion by 2035, with a CAGR of 6.66%, fueled by advances in early detection technologies and personalized medicine approaches.

Lisata and GATC Health Partner to Accelerate Drug Development Using AI Platform

Lisata Therapeutics and GATC Health launch strategic collaboration utilizing GATC's AI-powered Multiomics Advanced Technology platform to optimize drug development and improve success rates.

Endometriosis Clinical Trial Pipeline Shows Promise with 20+ Therapies in Development

• The endometriosis clinical trial landscape is robust, featuring over 15 companies developing more than 20 potential therapies. • Recent clinical trial activity includes positive Phase II results for Hope Medicine's HMI-115 and TiumBio's Merigolix, alongside Lisata Therapeutics' preclinical research. • Key companies like Kissei Pharmaceutical, Mithra Pharmaceuticals, and Organon are advancing novel treatments, including Linzagolix and Estelle, to address unmet needs. • These emerging therapies aim to improve pain management and overall outcomes for the estimated 190 million women affected by endometriosis worldwide.

Lisata Therapeutics Completes Enrollment in CENDIFOX Trial of Certepetide for Advanced Solid Tumors

Lisata Therapeutics has completed enrollment in the Phase 1b/2a CENDIFOX trial evaluating certepetide combined with FOLFIRINOX-based therapies.

Lisata Therapeutics Advances Clinical Trials, Anticipates Data-Rich 2025

Lisata Therapeutics is actively progressing its clinical trials, with significant data readouts expected in 2025, marking a potentially transformative period for the company.

Certepetide Shows Promise in Metastatic Pancreatic Cancer: Lisata Therapeutics Announces Encouraging Phase 2 Results

Lisata Therapeutics reported positive trends in overall survival for certepetide plus chemotherapy in metastatic pancreatic cancer patients.

FDA Grants Orphan Drug Designation to Certepetide for Cholangiocarcinoma

The FDA has granted orphan drug designation to certepetide for the treatment of cholangiocarcinoma, a rare and aggressive cancer with limited treatment options.

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