Cisplatin

Generic Name
Cisplatin
Brand Names
Platinol
Drug Type
Small Molecule
Chemical Formula
Cl2H6N2Pt
CAS Number
15663-27-1
Unique Ingredient Identifier
Q20Q21Q62J
Background

Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.

Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Associated Conditions
Advanced Ovarian Cancer, Ovarian Cancer Metastatic, Advanced Bladder cancer, Advanced Testicular cancer, Metastatic Testicular cancer
Associated Therapies
-

Adjuvant Chemoradiotherapy and Interferon Alfa in Treating Patients With Resected Pancreatic Cancer

First Posted Date
2003-05-07
Last Posted Date
2016-12-07
Lead Sponsor
Alliance for Clinical Trials in Oncology
Target Recruit Count
89
Registration Number
NCT00059826
Locations
🇺🇸

University of Florida Shands Cancer Center, Gainesville, Florida, United States

🇺🇸

Rush University Medical Center, Chicago, Illinois, United States

🇺🇸

James Graham Brown Cancer Center at University of Louisville, Louisville, Kentucky, United States

and more 11 locations

Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Advanced Cancer of the Oropharynx or Hypopharynx

Phase 3
Completed
Conditions
First Posted Date
2003-04-30
Last Posted Date
2021-02-21
Lead Sponsor
UNICANCER
Target Recruit Count
160
Registration Number
NCT00003627
Locations
🇫🇷

Centre Antoine Lacassagne, Nice, France

🇫🇷

Centre Regional de Lutte Contre le Cancer - Centre Val d'Aurelle, Montpellier, France

🇫🇷

Institut Jean Godinot, Reims, France

and more 8 locations

Combination Chemotherapy Followed by Radiation Therapy in Patients With Small Cell Lung Cancer

Phase 3
Completed
Conditions
First Posted Date
2003-04-16
Last Posted Date
2013-12-19
Lead Sponsor
Medical Research Council
Target Recruit Count
400
Registration Number
NCT00002822
Locations
🇬🇧

Medical Research Council Clinical Trials Unit, London, England, United Kingdom

Combination Chemotherapy, Interferon Alfa, and Interleukin-2 in Treating Patients With Metastatic Melanoma

Phase 2
Completed
Conditions
First Posted Date
2003-04-11
Last Posted Date
2012-07-02
Lead Sponsor
European Organisation for Research and Treatment of Cancer - EORTC
Target Recruit Count
90
Registration Number
NCT00002669
Locations
🇮🇹

Istituto Europeo Di Oncologia, Milano, Italy

🇦🇹

Landeskrankenanstalten - Salzburg, Salzburg, Austria

🇧🇪

U.Z. Gasthuisberg, Leuven, Belgium

and more 21 locations

Combination Chemotherapy and Surgery With or Without G-CSF in Treating Patients With Osteosarcoma

Phase 3
Completed
Conditions
First Posted Date
2003-04-10
Last Posted Date
2012-09-24
Lead Sponsor
European Organisation for Research and Treatment of Cancer - EORTC
Target Recruit Count
214
Registration Number
NCT00002539
Locations
🇳🇱

University Medical Center Nijmegen, Nijmegen, Netherlands

🇳🇱

Academisch Ziekenhuis Utrecht, Utrecht, Netherlands

🇧🇪

Institut Jules Bordet, Brussels (Bruxelles), Belgium

and more 13 locations

Chemotherapy Plus Radiation Therapy With or Without Surgery in Treating Patients With Stage IIIA Non-small Cell Lung Cancer

First Posted Date
2003-04-10
Last Posted Date
2015-11-17
Lead Sponsor
Radiation Therapy Oncology Group
Target Recruit Count
429
Registration Number
NCT00002550
Locations
🇺🇸

University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States

🇺🇸

Veterans Affairs Medical Center - Indianapolis (Roudebush), Indianapolis, Indiana, United States

🇺🇸

Indiana University Cancer Center, Indianapolis, Indiana, United States

and more 13 locations

BMS-247550 Plus Cisplatin in Treating Patients With Metastatic or Recurrent Head and Neck Cancer

Phase 1
Completed
Conditions
Interventions
First Posted Date
2003-04-09
Last Posted Date
2013-02-11
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
27
Registration Number
NCT00057850
Locations
🇺🇸

Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania, United States

Radiation Therapy With or Without Chemotherapy in Reducing Mouth Dryness in Patients With Nasopharyngeal Cancer

First Posted Date
2003-04-09
Last Posted Date
2017-02-17
Lead Sponsor
Radiation Therapy Oncology Group
Target Recruit Count
68
Registration Number
NCT00057785
Locations
🇺🇸

Siteman Cancer Center at Barnes-Jewish Hospital, St Louis, Missouri, United States

🇺🇸

Mayo Clinic Cancer Center, Rochester, Minnesota, United States

🇺🇸

Radiological Associates of Sacramento Medical Group, Incorporated, Sacramento, California, United States

and more 14 locations

S0227 Cisplatin With Either Paclitaxel or Gemcitabine in Recurrent, Persistent, or Metastatic Cervical Cancer

Phase 3
Withdrawn
Conditions
First Posted Date
2003-04-09
Last Posted Date
2012-06-13
Lead Sponsor
SWOG Cancer Research Network
Registration Number
NCT00057928
Locations
🇺🇸

Arizona Cancer Center, Tucson, Arizona, United States

🇺🇸

Veterans Affairs Medical Center - Little Rock (McClellan), Little Rock, Arkansas, United States

🇺🇸

Mayo Clinic, Jacksonville, Florida, United States

and more 103 locations

Comparison of Two Combination Chemotherapy Regimens in Treating Patients With Extensive-Stage Small Cell Lung Cancer

First Posted Date
2003-04-09
Last Posted Date
2023-07-05
Lead Sponsor
Eastern Cooperative Oncology Group
Target Recruit Count
140
Registration Number
NCT00057837
Locations
🇺🇸

Elkhart General Hospital, Elkhart, Indiana, United States

🇺🇸

Carle Cancer Center at Carle Foundation Hospital, Urbana, Illinois, United States

🇺🇸

St. Luke's Regional Medical Center, Sioux City, Iowa, United States

and more 75 locations
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