Cisplatin

Generic Name
Cisplatin
Brand Names
Platinol
Drug Type
Small Molecule
Chemical Formula
Cl2H6N2Pt
CAS Number
15663-27-1
Unique Ingredient Identifier
Q20Q21Q62J
Background

Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.

Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Associated Conditions
Advanced Ovarian Cancer, Ovarian Cancer Metastatic, Advanced Bladder cancer, Advanced Testicular cancer, Metastatic Testicular cancer
Associated Therapies
-

Intrathecal Radioimmunotherapy, Radiation Therapy, and Chemotherapy After Surgery in Treating Patients With Medulloblastoma

First Posted Date
2003-04-09
Last Posted Date
2020-05-11
Lead Sponsor
Memorial Sloan Kettering Cancer Center
Target Recruit Count
6
Registration Number
NCT00058370
Locations
🇺🇸

Memorial Sloan-Kettering Cancer Center, New York, New York, United States

🇺🇸

Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center, New York, New York, United States

Chemotherapy and Radiation Therapy With or Without Efaproxiral in Treating Patients With Stage III Non-Small Cell Lung Cancer

Phase 3
Withdrawn
Conditions
First Posted Date
2003-03-07
Last Posted Date
2013-05-10
Lead Sponsor
Spectrum Pharmaceuticals, Inc
Registration Number
NCT00055887
Locations
🇨🇦

CHUS-Hopital Fleurimont, Fleurimont, Quebec, Canada

🇺🇸

Schiffler Cancer Center, Wheeling, West Virginia, United States

🇨🇦

Centre Hospitalier Universitaire de Quebec, Quebec City, Quebec, Canada

and more 19 locations

Tipifarnib, Gemcitabine, and Cisplatin in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer

First Posted Date
2003-03-07
Last Posted Date
2013-06-04
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
48
Registration Number
NCT00055757
Locations
🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

Hospitalization Rates of Patients With Non-Small Cell Lung Cancer Treated With Gemcitabine and Either Cisplatin or Carboplatin

Phase 3
Conditions
First Posted Date
2003-03-07
Last Posted Date
2013-09-20
Lead Sponsor
The Christie NHS Foundation Trust
Target Recruit Count
400
Registration Number
NCT00055965
Locations
🇬🇧

Christie Hospital NHS Trust, Manchester, England, United Kingdom

S0121, Neoadjuvant Carboplatin, Paclitaxel, and Gemcitabine Followed by Cisplatin and Radiation Therapy in Treating Patients With Locally Advanced or Recurrent Carcinoma of the Urothelium

Phase 2
Completed
Conditions
First Posted Date
2003-03-07
Last Posted Date
2013-01-31
Lead Sponsor
SWOG Cancer Research Network
Target Recruit Count
7
Registration Number
NCT00055835
Locations
🇺🇸

Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio, United States

🇺🇸

MBCCOP - Gulf Coast, Mobile, Alabama, United States

🇺🇸

CCOP - Columbus, Columbus, Ohio, United States

and more 89 locations

Combination Chemotherapy and Radiation Therapy With/Without Surgery In Patients With Stage II/III Bladder Cancer

First Posted Date
2003-03-07
Last Posted Date
2018-06-15
Lead Sponsor
Radiation Therapy Oncology Group
Target Recruit Count
97
Registration Number
NCT00055601
Locations
🇺🇸

Utah Cancer Specialists at UCS Cancer Center, Salt Lake City, Utah, United States

🇺🇸

LDS Hospital, Salt Lake City, Utah, United States

Cisplatin and Gemcitabine Compared With Observation in Treating Patients Who Have Undergone Surgery for Bladder Cancer

Phase 3
Conditions
First Posted Date
2003-02-06
Last Posted Date
2013-12-18
Lead Sponsor
Fondazione C.N.R./Regione Toscana "G. Monasterio", Pisa, Italy
Target Recruit Count
700
Registration Number
NCT00054626
Locations
🇮🇹

Ospedale Civile Trapani, Trapani, Italy

🇮🇹

Ospedale Amedeo Savoia, Turin, Italy

🇮🇹

Istituto Nazionale Riposo e Cura Anziani Istituto, Ancona - AN, Italy

and more 146 locations

Chemotherapy and Radiation Therapy With or Without Surgery in Treating Patients With Stage I Cancer of the Cervix

Phase 3
Terminated
Conditions
First Posted Date
2003-02-06
Last Posted Date
2013-04-11
Lead Sponsor
Gynecologic Oncology Group
Registration Number
NCT00054067
Locations
🇺🇸

Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, United States

🇺🇸

University of Chicago Cancer Research Center, Chicago, Illinois, United States

🇺🇸

Ireland Cancer Center, Cleveland, Ohio, United States

and more 47 locations

S0216, Combination Chemotherapy and RT in Treating Patients With Stage III or Stage IV Head and Neck Cancer

Phase 2
Completed
Conditions
First Posted Date
2003-02-06
Last Posted Date
2011-07-25
Lead Sponsor
SWOG Cancer Research Network
Registration Number
NCT00054054
Locations
🇺🇸

MBCCOP - Gulf Coast, Mobile, Alabama, United States

🇺🇸

CCOP - Atlanta Regional, Atlanta, Georgia, United States

🇺🇸

Veterans Affairs Medical Center - Chicago (Westside Hospital), Chicago, Illinois, United States

and more 92 locations

Radiation Therapy and Chemotherapy in Treating Patients With Locally Advanced Cervical Cancer

First Posted Date
2003-02-06
Last Posted Date
2014-12-31
Lead Sponsor
Gynecologic Oncology Group
Target Recruit Count
11
Registration Number
NCT00054444
Locations
🇺🇸

MetroHealth Medical Center, Cleveland, Ohio, United States

🇺🇸

Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University Medical Center, Columbus, Ohio, United States

🇺🇸

University of Chicago Comprehensive Cancer Center, Chicago, Illinois, United States

and more 7 locations
© Copyright 2024. All Rights Reserved by MedPath