Cisplatin

Generic Name
Cisplatin
Brand Names
Platinol
Drug Type
Small Molecule
Chemical Formula
Cl2H6N2Pt
CAS Number
15663-27-1
Unique Ingredient Identifier
Q20Q21Q62J
Background

Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.

Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Associated Conditions
Advanced Ovarian Cancer, Ovarian Cancer Metastatic, Advanced Bladder cancer, Advanced Testicular cancer, Metastatic Testicular cancer
Associated Therapies
-

Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Metastatic Testicular Cancer

Phase 2
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-12-19
Lead Sponsor
Medical Research Council
Target Recruit Count
25
Registration Number
NCT00004077
Locations
🇬🇧

Velindre Hospital, Cardiff, Wales, United Kingdom

Combination Chemotherapy in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer

Phase 2
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-12-18
Lead Sponsor
Raghu Nandan, M.D., Inc
Registration Number
NCT00005825
Locations
🇺🇸

Rajendra Prasad M.D., Inc., Lakewood, California, United States

Combination Chemotherapy With or Without Interleukin-2 and Interferon Alfa in Treating Patients With Metastatic Melanoma

Phase 3
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2023-06-22
Lead Sponsor
Eastern Cooperative Oncology Group
Target Recruit Count
482
Registration Number
NCT00003027
Locations
🇺🇸

USC/Norris Comprehensive Cancer Center and Hospital, Los Angeles, California, United States

🇺🇸

Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, United States

🇺🇸

Veterans Affairs Medical Center - Chicago (Westside Hospital), Chicago, Illinois, United States

and more 91 locations

Chemotherapy and Radiation Therapy With or Without Surgery in Treating Patients With Head and Neck Cancer

First Posted Date
2003-01-27
Last Posted Date
2023-07-07
Lead Sponsor
Radiation Therapy Oncology Group
Target Recruit Count
743
Registration Number
NCT00047008
Locations
🇺🇸

McKay-Dee Hospital Center, Ogden, Utah, United States

🇺🇸

Waukesha Memorial Hospital Regional Cancer Center, Waukesha, Wisconsin, United States

🇺🇸

Bay Area Cancer Care Center at Bay Area Medical Center, Marinette, Wisconsin, United States

and more 192 locations

Combination Chemotherapy Plus Fluoxetine in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer

First Posted Date
2003-01-27
Last Posted Date
2016-07-04
Lead Sponsor
Alliance for Clinical Trials in Oncology
Target Recruit Count
21
Registration Number
NCT00005850
Locations
🇺🇸

Memorial Regional Hospital Comprehensive Cancer Center, Hollywood, Florida, United States

🇺🇸

Helen and Harry Gray Cancer Institute at Good Samaritan Medical Center, West Palm Beach, Florida, United States

🇺🇸

Fort Wayne Medical Oncology and Hematology, Incorporated, Fort Wayne, Indiana, United States

and more 40 locations

Chemotherapy in Treating Children With Liver Cancer

Phase 3
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-12-04
Lead Sponsor
Societe Internationale d'Oncologie Pediatrique
Target Recruit Count
260
Registration Number
NCT00003912
Locations
🇮🇹

Azienda Ospedaliera di Padova, Padova, Italy

Surgery With or Without Preoperative Chemotherapy in Treating Patients With Resectable Non-small Cell Lung Cancer

Phase 3
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-12-04
Lead Sponsor
Medical Research Council
Target Recruit Count
600
Registration Number
NCT00003159
Locations
🇬🇧

Medical Research Council Clinical Trials Unit, London, England, United Kingdom

🇬🇧

Royal Marsden NHS Foundation Trust - Surrey, Sutton, England, United Kingdom

S0008: Chemotherapy Plus Biological Therapy in Treating Patients With Melanoma

First Posted Date
2003-01-27
Last Posted Date
2015-03-25
Lead Sponsor
SWOG Cancer Research Network
Target Recruit Count
432
Registration Number
NCT00006237
Locations
🇺🇸

George Bray Cancer Center at the Hospital of Central Connecticut - New Britain Campus, New Britain, Connecticut, United States

🇺🇸

Mercy and Unity Cancer Center at Mercy Hospital, Coon Rapids, Minnesota, United States

🇺🇸

Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University Medical Center, Columbus, Ohio, United States

and more 293 locations

Surgery With or Without Radiation Therapy and Chemotherapy in Treating Patients With Esophageal Cancer

First Posted Date
2003-01-27
Last Posted Date
2020-03-30
Lead Sponsor
Federation Francophone de Cancerologie Digestive
Target Recruit Count
195
Registration Number
NCT00047112
Locations
🇧🇪

Institut Jules Bordet, Brussels, Belgium

🇧🇪

Hopital Universitaire Erasme, Brussels, Belgium

🇧🇪

Universitair Ziekenhuis Antwerpen, Edegem, Belgium

and more 68 locations
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